Metamizole
- Generic Name
- Metamizole
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C13H17N3O4S
- CAS Number
- 50567-35-6
- Unique Ingredient Identifier
- 934T64RMNJ
- Background
Metamizole (dipyrone) is a pyrazolone derivative that belongs to the group of nonacid nonopioids. It is considered a potent analgesic and antipyretic with favourable gastrointestinal tolerability. Metamizole was formerly marketed in the US as Dimethone tablets and injection, Protemp oral liquid, and other drug products, and was withdrawn due to its associati...
- Indication
Metamizole is banned in several countries, where it was previously used as a powerful analgesic and fever reducer. In countries where it is still available, metamizole is indicated for acute severe pain after injuries or surgeries, colic, tumor pain, and acute or severe pain symptoms, as well as high fever if other treatments are unsuccessful.
- Associated Conditions
- Severe Pain, Severe Fever
- Associated Therapies
- -
Pharmacokinetics of Intravenous Metamizole in Children Less Than 6 Years Old
- First Posted Date
- 2016-01-21
- Last Posted Date
- 2018-05-30
- Lead Sponsor
- University Children's Hospital Basel
- Target Recruit Count
- 33
- Registration Number
- NCT02660177
- Locations
- 🇨🇭
UKBB, Basel, Switzerland
Efficacy and Safety of Metamizole Versus Placebo as Antithermic Therapy in the Acute Phase of Ischemic Stroke
- First Posted Date
- 2014-07-09
- Last Posted Date
- 2014-07-10
- Lead Sponsor
- Boehringer Ingelheim
- Target Recruit Count
- 58
- Registration Number
- NCT02184260
Efficacy and Tolerability of Metamizol in Patients With Episodic Moderate Headache
- Conditions
- Interventions
- First Posted Date
- 2014-07-08
- Last Posted Date
- 2014-07-08
- Lead Sponsor
- Boehringer Ingelheim
- Target Recruit Count
- 417
- Registration Number
- NCT02183220
Metamizol for the Treatment of Neoplastic Chronic Pain
- Conditions
- Interventions
- First Posted Date
- 2014-07-08
- Last Posted Date
- 2014-07-18
- Lead Sponsor
- Boehringer Ingelheim
- Target Recruit Count
- 6
- Registration Number
- NCT02181920
Effect of Metamizole (Dipyrone) on Renal Function in Salt-depleted Healthy Subjects
- First Posted Date
- 2013-11-26
- Last Posted Date
- 2015-04-17
- Lead Sponsor
- University Hospital, Basel, Switzerland
- Target Recruit Count
- 15
- Registration Number
- NCT01995006
- Locations
- 🇨🇭
Phase I Research Unit, University Hospital, Basel, Switzerland
Paracetamol Versus Dipyrone After Pediatric Lower Abdominal Surgery in Children With Spinal Anesthesia
- Conditions
- Interventions
- First Posted Date
- 2013-05-21
- Last Posted Date
- 2013-05-21
- Lead Sponsor
- Baskent University
- Target Recruit Count
- 2
- Registration Number
- NCT01858402
Patient Preferences, Analgesic Delivery Method and Pain Reduction in Spine Patients
- Conditions
- Interventions
- First Posted Date
- 2010-12-21
- Last Posted Date
- 2020-05-27
- Lead Sponsor
- Western Galilee Hospital-Nahariya
- Registration Number
- NCT01263652
Study of the Effect of Dipyrone, Ibuprofen, Paracetamol and Parecoxib on the Platelet Aggregation in Analgetic Dosages
- Conditions
- Interventions
- First Posted Date
- 2008-10-01
- Last Posted Date
- 2008-10-01
- Lead Sponsor
- Ruhr University of Bochum
- Target Recruit Count
- 80
- Registration Number
- NCT00763997
- Locations
- 🇩🇪
BG University Hospital Bergmannsheil GmbH, Bochum, Germany
Drug Development Updates
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