Alnylam Pharmaceuticals

πŸ‡¬πŸ‡§United Kingdom
Ownership
-
Established
2002-01-01
Employees
-
Market Cap
$35.9B
Website
http://www.alnylam.com/

A Study of ALN-HSD in Healthy Adult Subjects and Adult Patients With Nonalcoholic Steatohepatitis (NASH)

Phase 1
Terminated
Conditions
Interventions
First Posted Date
2020-09-25
Last Posted Date
2024-05-17
Lead Sponsor
Alnylam Pharmaceuticals
Target Recruit Count
6
Registration Number
NCT04565717
Locations
πŸ‡¬πŸ‡§

Clinical Trial Site, London, United Kingdom

ConTTRibute: A Global Observational Study of Patients With Transthyretin (TTR)-Mediated Amyloidosis (ATTR Amyloidosis)

First Posted Date
2020-09-23
Last Posted Date
2024-12-10
Lead Sponsor
Alnylam Pharmaceuticals
Target Recruit Count
1500
Registration Number
NCT04561518
Locations
πŸ‡¨πŸ‡³

Clinical Trial Site, Taipei, Taiwan

A Multicenter Observational Study to Evaluate the Effectiveness of Patisiran in Patients With Polyneuropathy of ATTRv Amyloidosis With a V122I or T60A Mutation

First Posted Date
2019-12-17
Last Posted Date
2022-06-06
Lead Sponsor
Alnylam Pharmaceuticals
Target Recruit Count
67
Registration Number
NCT04201418
Locations
πŸ‡ΊπŸ‡Έ

Clinical Trial Site, Milwaukee, Wisconsin, United States

HELIOS-B: A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

First Posted Date
2019-11-06
Last Posted Date
2024-12-10
Lead Sponsor
Alnylam Pharmaceuticals
Target Recruit Count
655
Registration Number
NCT04153149
Locations
πŸ‡¬πŸ‡§

Clinical Trial Site, Middlesbrough, United Kingdom

A Study to Evaluate Lumasiran in Patients With Advanced Primary Hyperoxaluria Type 1

Phase 3
Active, not recruiting
Conditions
Interventions
First Posted Date
2019-11-05
Last Posted Date
2024-12-09
Lead Sponsor
Alnylam Pharmaceuticals
Target Recruit Count
21
Registration Number
NCT04152200
Locations
πŸ‡¦πŸ‡ͺ

Clinical Trial Site, Dubai, United Arab Emirates

Expanded Access Protocol to Provide Lumasiran to Patients With Primary Hyperoxaluria Type 1

First Posted Date
2019-10-14
Last Posted Date
2024-02-16
Lead Sponsor
Alnylam Pharmaceuticals
Registration Number
NCT04125472

Expanded Access Protocol of Givosiran for Patients With Acute Hepatic Porphyria

First Posted Date
2019-08-14
Last Posted Date
2024-05-20
Lead Sponsor
Alnylam Pharmaceuticals
Registration Number
NCT04056481

APOLLO-B: A Study to Evaluate Patisiran in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR Amyloidosis With Cardiomyopathy)

First Posted Date
2019-06-25
Last Posted Date
2024-12-09
Lead Sponsor
Alnylam Pharmaceuticals
Target Recruit Count
360
Registration Number
NCT03997383
Locations
πŸ‡¬πŸ‡§

Clinical Trial Site, Stockton-on-Tees, United Kingdom

A Study to Evaluate ALN-AGT01 in Patients With Hypertension

First Posted Date
2019-05-01
Last Posted Date
2023-01-17
Lead Sponsor
Alnylam Pharmaceuticals
Target Recruit Count
124
Registration Number
NCT03934307
Locations
πŸ‡¬πŸ‡§

Clinical Trial Site, Manchester, United Kingdom

A Study of Lumasiran in Infants and Young Children With Primary Hyperoxaluria Type 1

Phase 3
Active, not recruiting
Conditions
Interventions
First Posted Date
2019-04-05
Last Posted Date
2024-07-26
Lead Sponsor
Alnylam Pharmaceuticals
Target Recruit Count
18
Registration Number
NCT03905694
Locations
πŸ‡¬πŸ‡§

Clinical Trial Site, London, United Kingdom

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