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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

Effect of TRO19622 in the Treatment of Patients With Chemotherapy Induced Peripheral Neuropathy

Phase 2
Completed
Conditions
Chemotherapy-Induced Peripheral Neuropathy
Interventions
Drug: Placebo Control
First Posted Date
2009-04-06
Last Posted Date
2016-11-22
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
17
Registration Number
NCT00876538
Locations
🇫🇷

Centre Antoine Lacassagne, Nice, France

🇫🇷

C.R.L.C Val d'Aurelle Service d'Oncologie Médicale, Montpellier, France

🇫🇷

Centre Hospitalier de Versailles Hôpital André Mignot Service d'Hématologie-Oncologie, Le Chesnay, France

and more 5 locations

A Study of RO5024048 in Combination With Pegasys and Copegus in Treatment-Naive Patients With Chronic Hepatitis C, Genotype 1 or 4

Phase 2
Completed
Conditions
Hepatitis C, Chronic
Interventions
First Posted Date
2009-03-26
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
413
Registration Number
NCT00869661

Safety and Efficacy of TRO19622 as add-on Therapy to Riluzole Versus Placebo in Treatment of Patients Suffering From ALS

Phase 3
Completed
Conditions
Amyotrophic Lateral Sclerosis
Interventions
Drug: Placebo Comparator
First Posted Date
2009-03-24
Last Posted Date
2020-02-25
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
512
Registration Number
NCT00868166
Locations
🇧🇪

University Hospital Gasthuisberg - Dept Neurology - Herestraat 49, Leuven, Belgium

🇫🇷

Hôpital La Timone - Service Neurologie et Maladies Neuromusculaires, Marseille, France

🇫🇷

Clinique du Motoneurone - Sce d'Explorations Neurologiques - Hôpital Gui de Chauliac, Montpellier, France

and more 12 locations

A Study of Bevacizumab (Avastin) in Participants With Newly Diagnosed Locally Advanced Rectal Cancer

Phase 2
Completed
Conditions
Rectal Cancer
Interventions
Radiation: Preoperative Radiotherapy
Procedure: Surgery
First Posted Date
2009-03-19
Last Posted Date
2017-08-04
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
91
Registration Number
NCT00865189
Locations
🇫🇷

ICO Paul Papin; Oncologie Medicale., Angers, France

🇫🇷

HOPITAL JEAN MINJOZ; Oncologie, Besancon, France

🇫🇷

Hopital Saint Andre; Département de Radiothérapie Et D'Oncologie Médicale, Bordeaux, France

and more 17 locations

A Study to Assess the Effect of Tocilizumab on Signs and Symptoms in Patients With Rheumatoid Arthritis

Phase 3
Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2009-02-20
Last Posted Date
2017-08-03
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
29
Registration Number
NCT00848120
Locations
🇵🇭

Manila Doctors Hospital; Rheumatology Section, Manila, Philippines

🇵🇭

Jose Reyes Memorial Medical Center, Manila, Philippines

🇵🇭

Our Lady of Mount Carmel Medical Center, San Fernando, Philippines

and more 1 locations

A Study of Combination Treatment With MabThera (Rituximab) and RoActemra (Tocilizumab) Versus RoActemra in Patients With Rheumatoid Arthritis With an Incomplete Response to Methotrexate

Phase 2
Terminated
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2009-02-18
Last Posted Date
2014-12-24
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
24
Registration Number
NCT00845832

A Study of Avastin (Bevacizumab) in Combination With Taxane-based Chemotherapy as First Line Treatment in Patients With HER-2 Negative Breast Cancer

Phase 2
Completed
Conditions
Breast Cancer
Interventions
First Posted Date
2009-02-18
Last Posted Date
2014-07-23
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
90
Registration Number
NCT00846027

A Study of Trastuzumab Emtansine Versus Capecitabine + Lapatinib in Participants With HER2-positive Locally Advanced or Metastatic Breast Cancer

Phase 3
Completed
Conditions
Breast Cancer
Interventions
First Posted Date
2009-01-26
Last Posted Date
2016-10-31
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
991
Registration Number
NCT00829166

A Study of Obinutuzumab in Combination With Chemotherapy in Participants With CD20+ B-Cell Follicular Non-Hodgkin's Lymphoma

First Posted Date
2009-01-19
Last Posted Date
2016-11-04
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
137
Registration Number
NCT00825149
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