Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com

A Study of the Efficacy and Safety of Bevacizumab in Chinese Women With Newly Diagnosed, Previously Untreated Stage III or Stage IV Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

First Posted Date
2018-08-17
Last Posted Date
2024-10-03
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
100
Registration Number
NCT03635489
Locations
🇨🇳

the First Hospital of Jilin University, Changchun, China

🇨🇳

Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Nanjing City, China

🇨🇳

Tianjin Medical University General Hospital, Tianjin, China

and more 13 locations

Study to Assess the Safety, Pharmacokinetics, and Efficacy of Baloxavir Marboxil in Healthy Pediatric Participants With Influenza-Like Symptoms

Phase 3
Completed
Conditions
Interventions
First Posted Date
2018-08-14
Last Posted Date
2020-04-29
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
173
Registration Number
NCT03629184
Locations
🇺🇸

The Probe Medical Research, Los Angeles, California, United States

🇺🇸

Kentucky Pediatric Research Center, Bardstown, Kentucky, United States

🇺🇸

Orange County Research Institute, Ontario, California, United States

and more 34 locations

A Study Evaluating the Safety and Efficacy of Cobimetinib Plus Atezolizumab in BRAFV600 Wild-type Melanoma With Central Nervous System Metastases and Cobimetinib Plus Atezolizumab and Vemurafenib in BRAFV600 Mutation-positive Melanoma With Central Nervous System Metastases

First Posted Date
2018-08-10
Last Posted Date
2024-04-11
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
80
Registration Number
NCT03625141
Locations
🇧🇷

Instituto Nacional de Cancer - INCa; Oncologia, Rio de Janeiro, RJ, Brazil

🇧🇷

Oncosite - Centro de Pesquisa Clinica Em Oncologia Ltda, Ijui, RS, Brazil

🇧🇷

Hospital das Clinicas - UFRGS, Porto Alegre, RS, Brazil

and more 19 locations

A Study to Evaluate the Efficacy and Safety of Faricimab (RO6867461) in Participants With Diabetic Macular Edema (YOSEMITE)

First Posted Date
2018-08-09
Last Posted Date
2022-09-16
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
940
Registration Number
NCT03622580
Locations
🇺🇸

Orange County Retina Med Group, Santa Ana, California, United States

🇺🇸

Kaiser Permanente Riverside Medical Center, Riverside, California, United States

🇺🇸

Cumberland Valley Retina PC, Hagerstown, Maryland, United States

and more 181 locations

A Study to Evaluate the Efficacy and Safety of Faricimab (RO6867461) in Participants With Diabetic Macular Edema

First Posted Date
2018-08-09
Last Posted Date
2024-06-04
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
951
Registration Number
NCT03622593
Locations
🇨🇦

Toronto Retina Institute, Toronto, Ontario, Canada

🇨🇦

Unity Health Toronto, Toronto, Ontario, Canada

🇺🇸

Retina Consultants of Nevada, Las Vegas, Nevada, United States

and more 191 locations

A Study to Evaluate Scales for Repetitive and Restricted Behaviors in Children, Adolescents, and Adults With Autism Spectrum Disorder (ASD)

Phase 1
Completed
Conditions
Interventions
First Posted Date
2018-08-02
Last Posted Date
2022-06-21
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
144
Registration Number
NCT03611075
Locations
🇺🇸

PCSD Feighner Research, San Diego, California, United States

🇺🇸

Southwest Autism Research and Resource Center, Phoenix, Arizona, United States

🇺🇸

Harmonex Neuroscience Research, Dothan, Alabama, United States

and more 15 locations

This is an Extension Study of the Roche P-trials to Investigate Safety and Effectiveness of Ocrelizumab in Participants With Multiple Sclerosis (MS)

Phase 3
Active, not recruiting
Conditions
Interventions
First Posted Date
2018-07-26
Last Posted Date
2024-11-07
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
1500
Registration Number
NCT03599245
Locations
🇦🇷

Centro de Especialidades Neurológicas y Rehabilitación - CENyR, Buenos Aires, Argentina

🇧🇷

Instituto de Neurologia de Curitiba, Curitiba, PR, Brazil

🇧🇪

UZ Antwerpen, Edegem, Belgium

and more 159 locations

Study Investigating a Single Oral Dose of Fenebrutinib in Healthy Volunteers

Phase 1
Completed
Conditions
Interventions
First Posted Date
2018-07-24
Last Posted Date
2018-12-06
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
8
Registration Number
NCT03596632
Locations
🇺🇸

Covance Clinical Research Unit, Inc, Madison, Wisconsin, United States

Non-interventional Study of Ocrelizumab in Participants With Relapsing or Primary Progressive Multiple Sclerosis

Active, not recruiting
Conditions
Interventions
First Posted Date
2018-07-20
Last Posted Date
2024-12-05
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
1710
Registration Number
NCT03593590
Locations
🇧🇪

Revalidatie en MS Centrum, Overpelt, Belgium

🇧🇬

Multiprofile Hosp. for Active Treatment;National Cardiology Hosp., Sofia, Bulgaria

🇧🇬

"City Clinic UMHAC" EOOD, Sofia, Bulgaria

and more 161 locations

A Study to Provide Complementary Efficacy, Safety and Patient Reported Outcomes Data in Participants With Active Relapsing Forms of Multiple Sclerosis (MS) in a Pragmatic Setting

First Posted Date
2018-07-17
Last Posted Date
2022-01-11
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
423
Registration Number
NCT03589105
Locations
🇫🇷

CHU de la Timone - Hopital d Adultes; Service de Neurologie, Marseille, France

🇫🇷

Fondation Hopital Saint Joseph; Neurologie, Marseille, France

🇫🇷

Centre hospitalier Annecy Genevois Site St Julien; Neurologie, Metz Tessy, France

and more 43 locations
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