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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

An Expanded Access Program of Pegfilgrastim (Neulastim) in Participants With Non-Hodgkin's Lymphoma (NHL)

Phase 4
Completed
Conditions
Non-Hodgkin's Lymphoma
Interventions
Drug: Chemotherapy
Drug: Immunochemotherapy
First Posted Date
2016-05-25
Last Posted Date
2016-11-21
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
53
Registration Number
NCT02782845

A Pharmacokinetics, Pharmacodynamics and Safety Study of Warfarin in Combination With Tamiflu (Oseltamivir)

Phase 4
Completed
Conditions
Drug Therapy, Combination
Interventions
First Posted Date
2016-05-23
Last Posted Date
2016-10-26
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
20
Registration Number
NCT02780622

A Study of Erlotinib (Tarceva) in Participants With Non-Small Cell Lung Cancer (NSCLC)

Phase 2
Completed
Conditions
Non-Squamous Non-Small Cell Lung Cancer
Interventions
First Posted Date
2016-05-17
Last Posted Date
2016-08-08
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
264
Registration Number
NCT02774278

A Study to Detect V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF) V600 Mutation on Cell-Free Deoxyribonucleic Acid (cfDNA) From Plasma in Participants With Advanced Melanoma

Phase 2
Completed
Conditions
Metastatic Melanoma
Interventions
First Posted Date
2016-05-11
Last Posted Date
2019-08-28
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
40
Registration Number
NCT02768207
Locations
🇧🇪

UZ Brussel, Brussel, Belgium

🇧🇪

UZ Antwerpen, Edegem, Belgium

🇧🇪

Jessa Zkh (Campus Virga Jesse), Hasselt, Belgium

and more 11 locations

A Study of Recombinant Human Erythropoietin Beta (NeoRecormon) in Anemic Cancer Participants Treated With Chemotherapy

Phase 3
Completed
Conditions
Anemia
Interventions
Drug: r-HuEPO
First Posted Date
2016-05-10
Last Posted Date
2017-04-04
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
61
Registration Number
NCT02767765

A Study of Carboplatin Plus Etoposide With or Without Atezolizumab in Participants With Untreated Extensive-Stage (ES) Small Cell Lung Cancer (SCLC)

Phase 3
Completed
Conditions
Small Cell Lung Carcinoma
Interventions
First Posted Date
2016-05-05
Last Posted Date
2023-07-28
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
503
Registration Number
NCT02763579
Locations
🇺🇸

Florida Cancer Specialists - Fort Myers (Broadway), Fort Myers, Florida, United States

🇺🇸

Comprehensive Cancer Centers of Nevada - Eastern Avenue, Las Vegas, Nevada, United States

🇺🇸

Tennessee Oncology Chattanooga, Chattanooga, Tennessee, United States

and more 111 locations

Pegasys Long-Term Anti-Fibrotic Effect Co-Infection Trial (PERFECT)

Phase 3
Terminated
Conditions
HIV/HCV Coinfection
Interventions
Drug: Peginterferon Alfa-2
First Posted Date
2016-05-04
Last Posted Date
2016-09-07
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
19
Registration Number
NCT02762383

A Study to Determine Biopsy Rate in Participants With a First Relapse of Breast Cancer

Completed
Conditions
Breast Cancer
Interventions
Other: eBC treated participants
First Posted Date
2016-05-04
Last Posted Date
2017-02-01
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
76
Registration Number
NCT02761616
Locations
🇦🇷

Cemic; Oncologia Clinica, Buenos Aires, Argentina

🇦🇷

Hospital de Morón, Moron, Argentina

🇦🇷

CENICLAR, Rosario, Argentina

and more 1 locations

A Study to Evaluate Efficacy and Safety of Epoetin Beta (NeoRecormon®) in Anemic Participants With Breast Cancer Undergoing Chemotherapy

Phase 2
Completed
Conditions
Anemia
Interventions
First Posted Date
2016-05-04
Last Posted Date
2018-08-24
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
200
Registration Number
NCT02761642

Efficacy and Safety of Peg-Interferon Alpha-2a Plus Ribavirin in Genotype 1 Chronic Hepatitis C Participants Co-Infected With Human Immunodeficiency Virus

Phase 4
Completed
Conditions
Hepatitis C, Chronic
Interventions
Drug: Peg-Interferon Alpha-2A
First Posted Date
2016-05-04
Last Posted Date
2016-08-16
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
180
Registration Number
NCT02761629
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