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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

An Extension Study of Onartuzumab in Participants With Solid Tumors on Study Treatment Previously Enrolled in a Company Sponsored Study

Phase 3
Completed
Conditions
Solid Tumor
Interventions
First Posted Date
2015-07-02
Last Posted Date
2019-07-23
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
12
Registration Number
NCT02488330
Locations
🇫🇷

Hopital Roger Salengro, Lille, France

🇯🇵

National Hospital Organization Shikoku Cancer Center, Ehime, Japan

🇮🇹

Azienda Ospedaliero Universitaria San Giovanni Battista Di Torino, Torino, Piemonte, Italy

and more 7 locations

Study to Assess Safety and Efficacy of Atezolizumab (MPDL3280A) Compared to Best Supportive Care Following Chemotherapy in Patients With Lung Cancer [IMpower010]

Phase 3
Active, not recruiting
Conditions
Non-Small Cell Lung Cancer
Interventions
First Posted Date
2015-07-01
Last Posted Date
2025-03-30
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
1280
Registration Number
NCT02486718
Locations
🇪🇸

Hospital NisA 9 de Octubre, Valencia, Spain

🇨🇳

Zhejiang Cancer Hospital, Zhejiang, China

🇫🇷

Hôpital Universitaire Dupuytren, Limoges, France

and more 225 locations

MabThera (Rituximab) in Combination With CHOP (or CHOP-like) Chemotherapy in Patients With Aggressive B-Cell Lymphoma

Completed
Conditions
Lymphoma, Lymphoma, Large B-Cell, Diffuse, Non-Hodgkin's Lymphoma, Lymphoma, Non Hodgkin, Relapsed or Refractory Diffuse Large B-Cell Lymphoma
Interventions
First Posted Date
2015-07-01
Last Posted Date
2016-02-22
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
154
Registration Number
NCT02486952

A Proof-of-Concept Study of Faricimab (RO6867461) in Participants With Choroidal Neovascularization (CNV) Secondary to Age-Related Macular Degeneration (AMD)

Phase 2
Completed
Conditions
Choroidal Neovascularization
Interventions
First Posted Date
2015-06-30
Last Posted Date
2020-11-12
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
273
Registration Number
NCT02484690
Locations
🇺🇸

Retina Consultants, San Diego, Poway, California, United States

🇺🇸

New England Retina Associates, Hamden, Connecticut, United States

🇺🇸

Austin Retina Associates, Austin, Texas, United States

and more 49 locations

Study for Validation of Standardized Questionnaires on Depression and Investigation of the Frequency of Depression in Rheumatoid Arthritis (RA) Participants

Completed
Conditions
Rheumatoid Arthritis
First Posted Date
2015-06-30
Last Posted Date
2016-10-17
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
1292
Registration Number
NCT02485483

A Study of RO5186582 in Down Syndrome Among Children 6 to 11 Years of Age

Phase 2
Terminated
Conditions
Down Syndrome
Interventions
Drug: Placebo
First Posted Date
2015-06-30
Last Posted Date
2017-07-06
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
45
Registration Number
NCT02484703
Locations
🇺🇸

University of Wisconsin Hospital and Clinics, Madison, Wisconsin, United States

🇺🇸

Emory University School of Medicine; Department of Human Genetics & Pediatrics, Decatur, Georgia, United States

🇺🇸

Duke Clin Rsch Institute, Durham, North Carolina, United States

and more 6 locations

A Study of Pertuzumab in Participants With Prostate Cancer

Phase 2
Terminated
Conditions
Prostate Cancer
Interventions
First Posted Date
2015-06-24
Last Posted Date
2015-09-18
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
68
Registration Number
NCT02480010

Safety of Xeloda in Solid Tumours

Completed
Conditions
Metastatic Breast Cancer, Colon Cancer
Interventions
First Posted Date
2015-06-24
Last Posted Date
2017-02-17
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
1268
Registration Number
NCT02479217

A Study of Disease Progression in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration

Terminated
Conditions
Geographic Atrophy
Interventions
Other: No intervention
First Posted Date
2015-06-24
Last Posted Date
2019-08-20
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
296
Registration Number
NCT02479386
Locations
🇵🇱

Klinika Okulistyki Ogolnej w Lublinie, Lublin, Poland

🇵🇱

SPEKTRUM Osrodek Okulistyki Klinicznej, Wroclaw, Poland

🇺🇸

Northwest Arkansas Retina Associates, Springdale, Arkansas, United States

and more 88 locations

A Prospective Study to Collect High-Quality Documentation of Bleeds, Health-Related Quality of Life (HRQoL), and Safety Outcomes in Patients With Hemophilia A Treated With Standard-of-Care Treatment

Completed
Conditions
Hemophilia A
Interventions
Drug: FVIII Replacement
Drug: Bypassing Agents
First Posted Date
2015-06-22
Last Posted Date
2017-05-30
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
221
Registration Number
NCT02476942
Locations
🇺🇸

University of Colorado Denver, Children's Hospital, Aurora, Colorado, United States

🇺🇸

Santa Monica Oncology Center, Santa Monica, California, United States

🇺🇸

Georgetown Uni Medical Center; Lombardi Cancer Center, Washington, D.C., District of Columbia, United States

and more 32 locations
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