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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com
Introduction

Roche is a Swiss biopharmaceutical and diagnostic company. The firm's bestselling pharmaceutical products include a variety of oncology therapies from acquired partner Genentech, and its diagnostics group was bolstered by the acquisition of Ventana in 2008. Oncology products account for 50% of pharmaceutical sales, and centralized and point-of-care diagnostics for more than half of diagnostic-related sales.

A Study of Rituximab in Combination With Chemotherapy in Relapsed/Refractory Follicular Lymphoma

Completed
Conditions
Lymphoma, Follicular
Interventions
Drug: Chemotherapy
First Posted Date
2015-06-16
Last Posted Date
2017-08-01
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
41
Registration Number
NCT02472756
Locations
🇷🇸

Institute of Hematology, Belgrade, Serbia

🇷🇸

Clinical Center Kragujevac, Kragujevac, Serbia

🇷🇸

Clinic of Haematology Cc Nis, NIS, Serbia

and more 3 locations

A Study to Investigate the Effect of CYP3A Inhibition on the Pharmacokinetics of RG1662 in Healthy Subjects

Phase 1
Completed
Conditions
Healthy Patient Study
Interventions
First Posted Date
2015-06-12
Last Posted Date
2016-08-26
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
12
Registration Number
NCT02470832

Safety and Efficacy of Bevacizumab in Combination With Carboplatin and Paclitaxel for Metastatic, Recurrent or Persistent Cervical Cancer

Phase 2
Completed
Conditions
Cervical Cancer
Interventions
First Posted Date
2015-06-10
Last Posted Date
2019-06-03
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
152
Registration Number
NCT02467907
Locations
🇬🇷

IASO, Athens, Greece

🇨🇴

Oncólogos de Occidente, Pereira, Colombia

🇲🇽

Instituto Nacional de Cancerologia; Oncology, Distrito Federal, Mexico

and more 40 locations

A Study to Evaluate the Safety of Lebrikizumab Compared to Topical Corticosteroids in Adult Patients With Atopic Dermatitis

First Posted Date
2015-06-08
Last Posted Date
2020-01-27
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
55
Registration Number
NCT02465606
Locations
🇺🇸

Allergy and Asthma Relief Experts, Granada Hills, California, United States

🇺🇸

T. Joseph Raoof Md, Inc., Encino, California, United States

🇺🇸

Allergy and Asthma Associates of Southern California - CRN, Mission Viejo, California, United States

and more 16 locations

Rituximab in Combination With Fludarabine and Cyclophosphamide in Patients With Chronic Lymphocytic Leukemia

Completed
Conditions
Lymphocytic Leukemia, Chronic, Chronic Lymphocytic Leukemia, Cancer
Interventions
Other: No intervention
First Posted Date
2015-06-03
Last Posted Date
2016-11-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
22
Registration Number
NCT02461316

Rituximab Therapy in Follicular Lymphoma in Combination With Chemotherapy - REFLECT 1

Completed
Conditions
Follicular Lymphoma
Interventions
Radiation: Chemotherapy
First Posted Date
2015-06-03
Last Posted Date
2015-09-30
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
99
Registration Number
NCT02461290

A Study of Atezolizumab in Advanced Solid Tumors

First Posted Date
2015-06-01
Last Posted Date
2021-06-04
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
474
Registration Number
NCT02458638
Locations
🇮🇪

St Vincent'S Uni Hospital; Medical Oncology, Dublin, Ireland

🇳🇴

Oslo Universitetssykehus HF; Radiumhospitalet, Oslo, Norway

🇨🇭

Freiburger Spital; Onkologie, Fribourg, Switzerland

and more 45 locations

Disease Characteristics, Treatment Patterns and Clinical Outcomes in Patients With Newly Diagnosed Unresectable Stage IIIB/IV Non-Small Cell Lung Cancer (NSCLC) in China

Completed
Conditions
Non-Small Cell Lung Cancer, Lung Cancer, Cancer
Interventions
Other: No intervention
First Posted Date
2015-06-01
Last Posted Date
2018-11-09
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
1378
Registration Number
NCT02458651
Locations
🇨🇳

Sichuan Provincial Cancer Hospital, Chengdu, China

🇨🇳

Cancer Hospital Chinese Academy of Medical Sciences., Beijing, China

🇨🇳

the First Hospital of Jilin University, Changchun, China

and more 8 locations

A Study of Escalating Doses of DCDS0780A in Participants With Relapsed or Refractory B-Cell Non-Hodgkin's Lymphoma

Phase 1
Completed
Conditions
Non-Hodgkin's Lymphoma
Interventions
First Posted Date
2015-05-25
Last Posted Date
2019-08-29
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
66
Registration Number
NCT02453087
Locations
🇺🇸

Stanford Cancer Center, Stanford, California, United States

🇺🇸

New York University Cancer Cen, New York, New York, United States

🇺🇸

Medical Center of Aurora; Rocky Mountain Cancer Centers, Aurora, Colorado, United States

and more 4 locations

A Study of the Efficacy and Safety of Tocilizumab in Participants With Systemic Sclerosis (SSc)

Phase 3
Completed
Conditions
Systemic Sclerosis
Interventions
Drug: Placebo
First Posted Date
2015-05-25
Last Posted Date
2020-03-09
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
212
Registration Number
NCT02453256
Locations
🇧🇪

UZ Leuven Gasthuisberg, Leuven, Belgium

🇫🇷

Hopital Claude Huriez; Internal Medicine, Lille, France

🇺🇸

Joint & Muscle Research Institute, Charlotte, North Carolina, United States

and more 80 locations
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