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Roche Holding AG

Roche Holding AG logo
🇨🇭Switzerland
Ownership
Public
Established
1896-01-15
Employees
103.6K
Market Cap
$270.5B
Website
http://www.roche.com

Study to Evaluate Home Vision Testing in Participants Who Receive Ranibizumab (Lucentis®)

Completed
Conditions
Macular Edema
Macular Degeneration
Interventions
Other: Ranibizumab
First Posted Date
2015-04-17
Last Posted Date
2019-06-10
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
47
Registration Number
NCT02420132
Locations
🇺🇸

Rocky Mountain Retina, Salt Lake City, Utah, United States

Safety and Efficacy of Trastuzumab as Part of Breast Cancer Treatment Regimen

First Posted Date
2015-04-17
Last Posted Date
2022-10-12
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
110
Registration Number
NCT02419742
Locations
🇮🇳

Jehangir Clinical Development Centre Pvt. Ltd; Cancer Research Room, Pune, Maharashtra, India

🇮🇳

Manipal Hospital; Department of Oncology, Bangalore, Karnataka, India

🇮🇳

MAX Balaji Hospital, Delhi, India

and more 3 locations

A Study of Atezolizumab Compared With Gemcitabine Plus (+) Cisplatin or Carboplatin for PD-L1-Selected Participants With Stage IV Squamous Non-Small Cell Lung Cancer (NSCLC) (IMpower111)

Phase 3
Terminated
Conditions
Non-Small Cell Lung Cancer
Interventions
First Posted Date
2015-04-06
Last Posted Date
2019-02-15
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
8
Registration Number
NCT02409355
Locations
🇺🇸

University of Maryland, Baltimore, Maryland, United States

🇺🇸

California Cancer Associates for Research & Excellence, Inc., Encinitas, California, United States

🇺🇸

Marin Cancer Care Inc, Greenbrae, California, United States

and more 79 locations

A Study of Atezolizumab (MPDL3280A) Compared With a Platinum Agent (Cisplatin or Carboplatin) + (Pemetrexed or Gemcitabine) in Participants With Stage IV Non-Squamous or Squamous Non-Small Cell Lung Cancer (NSCLC) [IMpower110]

Phase 3
Completed
Conditions
Non-Squamous Non-Small Cell Lung Cancer, Squamous Non-Small Cell Lung Cancer
Interventions
First Posted Date
2015-04-06
Last Posted Date
2023-03-15
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
572
Registration Number
NCT02409342
Locations
🇫🇷

Centre D'oncologie de Gentilly, Nancy, France

🇫🇷

Centre Hospitalier Regional Sud Reunion, Saint-pierre, France

🇧🇷

Centro de Pesquisas Clinicas em Oncologia - CPCO, Cachoeiro de Itapemirim, ES, Brazil

and more 139 locations

Safety Study of Rituximab (SC) Administered in Participants With CD20+ DLBCL or CD20+ Follicular NHL Grade 1 to 3A

First Posted Date
2015-04-02
Last Posted Date
2024-11-21
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
139
Registration Number
NCT02406092
Locations
🇲🇦

Hôpital d'enfants de Rabat - Service d'hémato-oncologie pédiatrique, Rabat, Morocco

🇩🇿

Hôpital Dorban CHU Annaba, Service d'Hématologie, Annaba, Algeria

🇩🇿

Centre hospitalo-univerisitaire de Tizi Ouzou - Nedir Mohamed;Service d'hématologie, Tizi Ouzou, Algeria

and more 10 locations

Comparing Continuous Subcutaneous Insulin Infusion With Multiple Daily Injections to Reach HbA1c Targets in Children and Adolescents With Type 1 Diabetes

Not Applicable
Completed
Conditions
Diabetes Mellitus Type 1
Interventions
Device: Accu-Chek Insight Pump System
First Posted Date
2015-03-31
Last Posted Date
2017-11-27
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
43
Registration Number
NCT02403375
Locations
🇦🇹

Medical University Graz, Graz, Austria

🇩🇪

Kinderkrankenhaus auf der Bult, Hannover, Germany

🇦🇹

Medical University of Vienna-Dept of Pediatrics, Vienna, Austria

and more 6 locations

Open-Label Extension and Safety Study for Participants With Crohn's Disease Previously Enrolled in the Etrolizumab Phase III Study GA29144

Phase 3
Terminated
Conditions
Crohn Disease
Interventions
First Posted Date
2015-03-31
Last Posted Date
2024-12-02
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
790
Registration Number
NCT02403323
Locations
🇭🇺

Semmelweis Egyetem; Belgyogyaszati es Hematologiai Klinika, Budapest, Hungary

🇺🇸

Valley Gastroenterology Consultants, Arcadia, California, United States

🇺🇸

University of California San Diego Medical Center, La Jolla, California, United States

and more 284 locations

Non-Interventional Study of Tocilizumab Subcutaneous (SC) Monotherapy in Participants With Rheumatoid Arthritis (RA)

Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2015-03-30
Last Posted Date
2019-12-06
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
353
Registration Number
NCT02402686
Locations
🇭🇺

National Institute of Rheumatology and Physiotherapy; 4Th Rheumatology Department, Budapest, Hungary

🇭🇺

Budai Irgalmasrendi Kórház KHT. II. Reumatológia, Budapest, Hungary

🇭🇺

Szent Andras Reumakorhaz; Reumatologia, Heviz, Hungary

and more 15 locations

Phase IIIb Study to Evaluate the Safety and Tolerability of Herceptin SC With Perjeta and Docetaxel in Patients With HER2-positive Advanced Breast Cancer

Phase 3
Completed
Conditions
Breast Cancer
Interventions
First Posted Date
2015-03-30
Last Posted Date
2019-09-06
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
418
Registration Number
NCT02402712
Locations
🇵🇱

MAGODENT Sp. z o.o., Warsaw, Poland

🇫🇷

Pole Sante Republique; Pharmacie Oncologique, Clermont Ferrand, France

🇩🇪

Studienzentrum Aschaffenburg, Aschaffenburg, Germany

and more 109 locations

A Study of Disease Progression in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration

Terminated
Conditions
Geographic Atrophy
Interventions
Other: No intervention
First Posted Date
2015-03-26
Last Posted Date
2019-08-09
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
202
Registration Number
NCT02399072
Locations
🇺🇸

Midwest Vision Research Foundation, Chesterfield, Missouri, United States

🇺🇸

Retina Consultants of Houston, The Woodlands, Texas, United States

🇺🇸

Retina Assoc of Cleveland Inc, Cleveland, Ohio, United States

and more 60 locations
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