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Alliance for Clinical Trials in Oncology

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 2011-01-01

Employees: 251

Market Cap: -

Website: https://www.allianceforclinicaltrialsinoncology.org

Clinical Trials

Management of Tobacco Treatment Intervention in Reducing Surgical Complications in Patients With Newly Diagnosed Lung Cancer Who Smoke Cigarettes

Phase 3

Terminated

Conditions: Lung Carcinoma

Interventions: Drug: Placebo
Drug: Varenicline
Other: Tobacco Cessation Counseling

First Posted Date: 2016-08-05

Last Posted Date: 2022-07-27

Lead Sponsor: Alliance for Clinical Trials in Oncology

Target Recruit Count: 23

Registration Number: NCT02856581

Locations: 🇺🇸
Fairbanks Memorial Hospital, Fairbanks, Alaska, United States
🇺🇸
Kingman Regional Medical Center, Kingman, Arizona, United States
🇺🇸
Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro, Jonesboro, Arkansas, United States

and more 371 locations

Combination Chemotherapy With or Without Hypofractionated Radiation Therapy Before Surgery in Treating Patients With Pancreatic Cancer

Phase 2

Conditions: Pancreatic Adenocarcinoma
Borderline Resectable Adenocarcinoma of the Head of the Pancrease

Interventions: Procedure: surgery
Radiation: radiation therapy
Drug: mFOLFIRINOX
Drug: FOLFOX

First Posted Date: 2016-07-20

Last Posted Date: 2022-05-24

Lead Sponsor: Alliance for Clinical Trials in Oncology

Target Recruit Count: 126

Registration Number: NCT02839343

Locations: 🇺🇸
Southern Cancer Center PC-Mobile, Mobile, Alabama, United States
🇺🇸
Southern Cancer Center PC-Springhill, Mobile, Alabama, United States
🇺🇸
University of South Alabama Mitchell Cancer Institute, Mobile, Alabama, United States

and more 152 locations

Breast Cancer WEight Loss Study (BWEL Study)

Phase 3

Active, not recruiting

Conditions: Breast Carcinoma

First Posted Date: 2016-04-26

Last Posted Date: 2025-01-13

Lead Sponsor: Alliance for Clinical Trials in Oncology

Target Recruit Count: 3177

Registration Number: NCT02750826

Locations: 🇺🇸
Southern Cancer Center PC-Daphne, Daphne, Alabama, United States
🇺🇸
Southern Cancer Center PC-Mobile, Mobile, Alabama, United States
🇺🇸
Southern Cancer Center PC-Providence, Mobile, Alabama, United States

and more 1486 locations

Enzalutamide for Patients With Androgen Receptor Positive Salivary Cancers

Phase 2

Conditions: Salivary Cancer

Interventions: Drug: enzalutamide

First Posted Date: 2016-04-25

Last Posted Date: 2021-10-26

Lead Sponsor: Alliance for Clinical Trials in Oncology

Target Recruit Count: 46

Registration Number: NCT02749903

Locations: 🇺🇸
Anchorage Associates in Radiation Medicine, Anchorage, Alaska, United States
🇺🇸
Anchorage Radiation Therapy Center, Anchorage, Alaska, United States
🇺🇸
Alaska Breast Care and Surgery LLC, Anchorage, Alaska, United States

and more 284 locations

Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas

Phase 2

Recruiting

Conditions: Intracranial Meningioma
Recurrent Meningioma
NF2 Gene Mutation

Interventions: Drug: Abemaciclib
Drug: Capivasertib
Drug: FAK Inhibitor GSK2256098
Drug: Vismodegib

First Posted Date: 2015-08-14

Last Posted Date: 2025-06-26

Lead Sponsor: Alliance for Clinical Trials in Oncology

Target Recruit Count: 124

Registration Number: NCT02523014

Locations: 🇺🇸
University of Alabama at Birmingham Cancer Center, Birmingham, Alabama, United States
🇺🇸
Anchorage Associates in Radiation Medicine, Anchorage, Alaska, United States
🇺🇸
Anchorage Radiation Therapy Center, Anchorage, Alaska, United States

and more 764 locations

Ixazomib Citrate, Lenalidomide, Dexamethasone, and Zoledronic Acid or Zoledronic Acid Alone After Radiation Therapy in Treating Patients With Solitary Plasmacytoma of Bone

Phase 3

Active, not recruiting

Conditions: Solitary Osseous Plasmacytoma

Interventions: Drug: ixazomib
Drug: lenalidomide
Drug: dexamethasone
Drug: zoledronic acid

First Posted Date: 2015-08-05

Last Posted Date: 2021-08-17

Lead Sponsor: Alliance for Clinical Trials in Oncology

Target Recruit Count: 11

Registration Number: NCT02516423

Locations: 🇺🇸
Anchorage Associates in Radiation Medicine, Anchorage, Alaska, United States
🇺🇸
Anchorage Radiation Therapy Center, Anchorage, Alaska, United States
🇺🇸
Alaska Breast Care and Surgery LLC, Anchorage, Alaska, United States

and more 385 locations

Corticosteroids + Bevacizumab vs. Corticosteroids + Placebo (BEST) for Radionecrosis After Radiosurgery for Brain Metastases

Phase 2

Terminated

Conditions: Brain Metastases
Radionecrosis

Interventions: Drug: bevacizumab
Drug: corticosteroids
Other: placebo

First Posted Date: 2015-07-07

Last Posted Date: 2023-03-23

Lead Sponsor: Alliance for Clinical Trials in Oncology

Target Recruit Count: 19

Registration Number: NCT02490878

Locations: 🇺🇸
Anchorage Associates in Radiation Medicine, Anchorage, Alaska, United States
🇺🇸
Anchorage Radiation Therapy Center, Anchorage, Alaska, United States
🇺🇸
Alaska Breast Care and Surgery LLC, Anchorage, Alaska, United States

and more 338 locations

FDG-PET Directed Treatment in Improving Response in Patients With Locally Advanced Stomach or Gastroesophageal Junction Cancer

Phase 2

Terminated

Conditions: Adenocarcinoma of the Gastroesophageal Junction
Gastric Adenocarcinoma
Gastric Cancer

Interventions: Procedure: surgery
Procedure: FDG-PET
Drug: 5-FU
Drug: docetaxel
Drug: capecitabine
Radiation: 3D-CRT
Drug: Irinotecan
Radiation: IMRT

First Posted Date: 2015-06-30

Last Posted Date: 2025-01-20

Lead Sponsor: Alliance for Clinical Trials in Oncology

Target Recruit Count: 5

Registration Number: NCT02485834

Locations: 🇺🇸
Los Angeles County-USC Medical Center, Los Angeles, California, United States
🇺🇸
USC / Norris Comprehensive Cancer Center, Los Angeles, California, United States
🇺🇸
Saint Helena Hospital, Saint Helena, California, United States

and more 68 locations

Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients with Relapsed or Refractory Germ Cell Tumors

Phase 3

Active, not recruiting

Conditions: Germ Cell Tumor
Teratoma
Choriocarcinoma
Germinoma
Mixed Germ Cell Tumor
Yolk Sac Tumor
Childhood Teratoma
Malignant Germ Cell Neoplasm
Extragonadal Seminoma
Non-seminomatous Germ Cell Tumor

Interventions: Drug: paclitaxel
Drug: ifosfamide
Drug: cisplatin
Drug: pegylated G-CSF
Drug: G-CSF
Drug: carboplatin
Drug: etoposide phosphate
Procedure: stem cell reinfusion

First Posted Date: 2015-03-02

Last Posted Date: 2025-01-13

Lead Sponsor: Alliance for Clinical Trials in Oncology

Target Recruit Count: 420

Registration Number: NCT02375204

Locations: 🇺🇸
Children's Hospital of Alabama, Birmingham, Alabama, United States
🇺🇸
UC San Diego Moores Cancer Center, La Jolla, California, United States
🇺🇸
Loma Linda University Medical Center, Loma Linda, California, United States

and more 122 locations

Early Palliative Care With Standard Care or Standard Care Alone in Improving Quality of Life of Patients With Incurable Lung or Non-colorectal Gastrointestinal Cancer and Their Family Caregivers

Phase 3

Completed

Conditions: Small Cell Lung Cancer
Extrahepatic Bile Duct Cancer
Malignant Mesothelioma
Non-small Cell Lung Cancer
Depression
Anxiety Disorder
Gastric Cancer
Liver Cancer
Pancreatic Cancer
Esophageal Cancer

First Posted Date: 2015-01-28

Last Posted Date: 2025-02-07

Lead Sponsor: Alliance for Clinical Trials in Oncology

Target Recruit Count: 405

Registration Number: NCT02349412

Locations: 🇺🇸
UC San Diego Moores Cancer Center, La Jolla, California, United States
🇺🇸
Queen's Medical Center, Honolulu, Hawaii, United States
🇺🇸
University of Chicago Comprehensive Cancer Center, Chicago, Illinois, United States

and more 20 locations

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