Cisplatin and Combination Chemotherapy in Treating Children and Young Adults With Hepatoblastoma or Liver Cancer After Surgery
- Conditions
- Childhood Malignant Liver NeoplasmHepatoblastomaFibrolamellar CarcinomaChildhood Hepatocellular CarcinomaHepatocellular Malignant Neoplasm, Not Otherwise Specified
- Interventions
- Procedure: Biospecimen CollectionOther: Patient ObservationProcedure: Resection
- First Posted Date
- 2018-05-23
- Last Posted Date
- 2025-06-29
- Lead Sponsor
- Children's Oncology Group
- Target Recruit Count
- 537
- Registration Number
- NCT03533582
- Locations
- πΊπΈ
Children's Hospital of Alabama, Birmingham, Alabama, United States
πΊπΈProvidence Alaska Medical Center, Anchorage, Alaska, United States
πΊπΈBanner Children's at Desert, Mesa, Arizona, United States
Pevonedistat, Irinotecan, and Temozolomide in Treating Patients With Recurrent or Refractory Solid Tumors or Lymphoma
- Conditions
- Recurrent LymphomaRecurrent Malignant Solid NeoplasmRecurrent Primary Central Nervous System NeoplasmRefractory LymphomaRefractory Malignant Solid NeoplasmRefractory Primary Central Nervous System Neoplasm
- Interventions
- First Posted Date
- 2017-10-26
- Last Posted Date
- 2024-10-22
- Lead Sponsor
- Children's Oncology Group
- Target Recruit Count
- 30
- Registration Number
- NCT03323034
- Locations
- πΊπΈ
Children's Healthcare of Atlanta - Arthur M Blank Hospital, Atlanta, Georgia, United States
πΊπΈChildren's Hospital of Alabama, Birmingham, Alabama, United States
πΊπΈChildren's Hospital Los Angeles, Los Angeles, California, United States
Pepinemab in Treating Younger Patients With Recurrent, Relapsed, or Refractory Solid Tumors
- Conditions
- Refractory OsteosarcomaRecurrent Malignant Solid NeoplasmRecurrent OsteosarcomaRefractory Malignant Solid Neoplasm
- Interventions
- Other: Laboratory Biomarker AnalysisBiological: PepinemabOther: Pharmacological Study
- First Posted Date
- 2017-10-25
- Last Posted Date
- 2024-07-15
- Lead Sponsor
- Children's Oncology Group
- Target Recruit Count
- 26
- Registration Number
- NCT03320330
- Locations
- πΊπΈ
Children's Hospital of Alabama, Birmingham, Alabama, United States
πΊπΈChildren's Hospital Los Angeles, Los Angeles, California, United States
πΊπΈChildren's Hospital of Orange County, Orange, California, United States
Genetic Mutational Analysis of Saliva or Buccal Mucosa Samples From Patients With Embryonal or Alveolar Rhabdomyosarcoma
- Conditions
- Embryonal RhabdomyosarcomaAlveolar Rhabdomyosarcoma
- Interventions
- Procedure: Biospecimen CollectionOther: Laboratory Biomarker AnalysisOther: Questionnaire Administration
- First Posted Date
- 2017-09-28
- Last Posted Date
- 2025-01-30
- Lead Sponsor
- Children's Oncology Group
- Target Recruit Count
- 900
- Registration Number
- NCT03296371
- Locations
- πΊπΈ
Childrens Oncology Group, Philadelphia, Pennsylvania, United States
Web-Based Physical Activity Intervention in Improving Long Term Health in Children and Adolescents With Cancer
- Conditions
- Malignant Solid NeoplasmCarcinoma In SituHematopoietic and Lymphatic System Neoplasm
- Interventions
- Other: Educational InterventionOther: Internet-Based InterventionOther: Laboratory Biomarker AnalysisDevice: Medical Device Usage and EvaluationOther: Quality-of-Life AssessmentOther: Questionnaire Administration
- First Posted Date
- 2017-07-21
- Last Posted Date
- 2025-04-18
- Lead Sponsor
- Children's Oncology Group
- Target Recruit Count
- 300
- Registration Number
- NCT03223753
- Locations
- πΊπΈ
Children's Hospital of Alabama, Birmingham, Alabama, United States
πΊπΈBanner Children's at Desert, Mesa, Arizona, United States
πΊπΈPhoenix Childrens Hospital, Phoenix, Arizona, United States
Biospecimen Analysis in Determining Effects of Chemotherapy on Fertility in Osteosarcoma Survivors
- Conditions
- Osteosarcoma
- Interventions
- Procedure: Biospecimen CollectionOther: Laboratory Biomarker AnalysisOther: Questionnaire Administration
- First Posted Date
- 2017-07-02
- Last Posted Date
- 2024-08-26
- Lead Sponsor
- Children's Oncology Group
- Target Recruit Count
- 224
- Registration Number
- NCT03206450
- Locations
- πΊπΈ
Children's Hospital of Alabama, Birmingham, Alabama, United States
πΊπΈPhoenix Childrens Hospital, Phoenix, Arizona, United States
πΊπΈBanner University Medical Center - Tucson, Tucson, Arizona, United States
Cancer Care Delivery in Adolescent and Young Adult Patients With Acute Lymphoblastic Leukemia
- Conditions
- Acute Lymphoblastic Leukemia
- Interventions
- Behavioral: DiscussionOther: Medical Chart ReviewOther: Questionnaire Administration
- First Posted Date
- 2017-07-02
- Last Posted Date
- 2025-01-06
- Lead Sponsor
- Children's Oncology Group
- Target Recruit Count
- 301
- Registration Number
- NCT03204916
- Locations
- πΊπΈ
Kaiser Permanente South Bay, Harbor City, California, United States
πΊπΈKaiser Permanente Sacramento Medical Center, Sacramento, California, United States
πΊπΈSaint Joseph Hospital - Cancer Centers of Colorado, Denver, Colorado, United States
Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)
- Conditions
- GanglioneuroblastomaNeuroblastoma
- Interventions
- Procedure: Autologous Hematopoietic Stem Cell TransplantationProcedure: Biospecimen CollectionProcedure: Bone Marrow Aspiration and BiopsyProcedure: Computed TomographyProcedure: EchocardiographyRadiation: External Beam Radiation TherapyRadiation: Iobenguane I-123Radiation: Iobenguane I-131Procedure: Multigated Acquisition ScanProcedure: Positron Emission TomographyProcedure: Magnetic Resonance ImagingProcedure: Therapeutic Conventional Surgery
- First Posted Date
- 2017-04-25
- Last Posted Date
- 2025-06-10
- Lead Sponsor
- Children's Oncology Group
- Target Recruit Count
- 724
- Registration Number
- NCT03126916
- Locations
- πΊπΈ
Children's Hospital of Alabama, Birmingham, Alabama, United States
πΊπΈPhoenix Childrens Hospital, Phoenix, Arizona, United States
πΊπΈArkansas Children's Hospital, Little Rock, Arkansas, United States
Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors
- Conditions
- Stage I Ovarian ChoriocarcinomaStage I Testicular Embryonal Carcinoma AJCC v6 and v7Stage I Testicular Seminoma AJCC v6 and v7Stage II Ovarian Yolk Sac Tumor AJCC v6 and v7Stage II Testicular Yolk Sac Tumor AJCC v6 and v7Stage III Ovarian ChoriocarcinomaStage III Testicular Choriocarcinoma AJCC v6 and v7Stage III Testicular Yolk Sac Tumor AJCC v6 and v7Stage IV Ovarian ChoriocarcinomaStage IV Ovarian Embryonal Carcinoma AJCC v6 and v7
- Interventions
- Procedure: BiopsyOther: Best PracticeProcedure: Biospecimen CollectionProcedure: Computed TomographyProcedure: Magnetic Resonance ImagingOther: Pharmacogenomic StudyProcedure: Pulmonary Function TestOther: Quality-of-Life AssessmentOther: Questionnaire Administration
- First Posted Date
- 2017-03-01
- Last Posted Date
- 2025-03-19
- Lead Sponsor
- Children's Oncology Group
- Target Recruit Count
- 2097
- Registration Number
- NCT03067181
- Locations
- πΊπΈ
Children's Hospital of Alabama, Birmingham, Alabama, United States
πΊπΈUSA Health Strada Patient Care Center, Mobile, Alabama, United States
πΊπΈAnchorage Associates in Radiation Medicine, Anchorage, Alaska, United States
Late Effects After Treatment in Patients With Previously Diagnosed High-Risk Neuroblastoma
- Conditions
- Recurrent NeuroblastomaStage 2A NeuroblastomaStage 4S NeuroblastomaStage 2B NeuroblastomaStage 4 NeuroblastomaStage 3 Neuroblastoma
- Interventions
- Other: Cytology Specimen Collection ProcedureOther: Laboratory Biomarker AnalysisOther: Quality-of-Life Assessment
- First Posted Date
- 2017-02-20
- Last Posted Date
- 2024-10-29
- Lead Sponsor
- Children's Oncology Group
- Target Recruit Count
- 376
- Registration Number
- NCT03057626
- Locations
- πΊπΈ
Children's Hospital of Alabama, Birmingham, Alabama, United States
πΊπΈPhoenix Childrens Hospital, Phoenix, Arizona, United States
πΊπΈArkansas Children's Hospital, Little Rock, Arkansas, United States