Ketorolac

Generic Name
Ketorolac
Brand Names
Acular, Acuvail, Omidria, Readysharp Anesthetics Plus Ketorolac, Sprix, Toradol, Toronova Suik
Drug Type
Small Molecule
Chemical Formula
C15H13NO3
CAS Number
74103-06-3
Unique Ingredient Identifier
YZI5105V0L
Background

Ketorolac is a Non-steroidal anti-inflammatory drug (NSAID) and is commercially available as an oral tablet, injectable, nasal spray and as an ophthalmic solution.
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Indication

Ketorolac is a Non-steroidal anti-inflammatory drug (NSAID) and has antipyretic, analgesic and anti-inflammatory properties. It is indicated for short term management of acute pain that requires the calibre of pain management offered by opioids. Clinicians may choose to initiate ketorolac to manage post-operative pain, spinal and soft tissue pain, rheumatoid...

Associated Conditions
Acute Migraine, Eye Pain, Inflammation, Macular Edema, Cystoid, Ocular Itching, Pericarditis Acute, Pseudophakic Cystoid Macular Oedema, Severe Acute Pain, Acute, moderate Pain, Chronic aphakic cystoid macular edema, Intraoperative miosis, Postoperative ocular pain
Associated Therapies
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Clinical Trials
Related News

"NSAIDs vs. Opiates: Which is More Effective in Managing Pain in Mild to Moderate Acute Pancreatitis?

Early Phase 1
Recruiting
Conditions
Acute Pancreatitis
Interventions
Drug: Ketorolac
Drug: Tramadol
First Posted Date
2023-03-06
Last Posted Date
2023-04-06
Lead Sponsor
Hayatabad Medical Complex
Target Recruit Count
130
Registration Number
NCT05756504
Locations
🇵🇰

Hayatabad Medical Complex, Peshawar, Kpk, Pakistan

Comparison of Ketorolac at Three Doses in Children With Acute Pain

First Posted Date
2022-12-07
Last Posted Date
2023-09-06
Lead Sponsor
Hamilton Health Sciences Corporation
Target Recruit Count
171
Registration Number
NCT05641363
Locations
🇨🇦

McMaster Children's Hospital, Hamilton, Ontario, Canada

🇨🇦

McMaster University Medical Centre, Hamilton, Ontario, Canada

Opioid-Free Pain Control Regimen Following Robotic Radical Prostatectomy

First Posted Date
2022-10-28
Last Posted Date
2024-04-18
Lead Sponsor
Wake Forest University Health Sciences
Target Recruit Count
100
Registration Number
NCT05597878
Locations
🇺🇸

Atrium Health Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem, North Carolina, United States

Ketorolac Intravenous Regional Analgesia in Lower Limb Surgeries

Not Applicable
Recruiting
Conditions
Postoperative Pain, Acute
Interventions
Drug: Ketorolac
Other: Control
First Posted Date
2022-09-16
Last Posted Date
2024-02-06
Lead Sponsor
Mansoura University
Target Recruit Count
76
Registration Number
NCT05543785
Locations
🇪🇬

Mansoura University Hospitals, Mansoura, Egypt

Paracetamol Compared With Ketorolac for Post-operative Analgetic

Phase 4
Completed
Conditions
Pain, Postoperative
Interventions
Drug: Paracetamol
Drug: Ketorolac
First Posted Date
2022-08-31
Last Posted Date
2022-09-06
Lead Sponsor
Indonesia University
Target Recruit Count
85
Registration Number
NCT05523102
Locations
🇮🇩

Cipto Mangunkusumo Hospital, Jakarta Pusat, DKI Jakarta, Indonesia

Opioid-Free Pain Protocol After Shoulder Arthroplasty

First Posted Date
2022-08-05
Last Posted Date
2024-01-12
Lead Sponsor
Henry Ford Health System
Target Recruit Count
80
Registration Number
NCT05488847
Locations
🇺🇸

Henry Ford Health, Detroit, Michigan, United States

Multi-Modal Anesthesia Protocol in Pain Management of Patients Undergoing Posterior Lumbar Spinal Fusion Surgery

First Posted Date
2022-06-10
Last Posted Date
2022-06-10
Lead Sponsor
University of Puerto Rico
Target Recruit Count
100
Registration Number
NCT05413902
Locations
🇵🇷

Puerto Rico Medical Center - University District Hospital, San Juan, Puerto Rico

Effect of Paracetamol and Ketorolac on RANK-L Levels in Patients Starting Orthodontic Treatment

Phase 4
Conditions
Malocclusion
Pain, Acute
Interventions
Drug: Ketorolac
First Posted Date
2022-05-20
Last Posted Date
2022-05-20
Lead Sponsor
University of Guadalajara
Target Recruit Count
24
Registration Number
NCT05383820
Locations
🇲🇽

Juan Ramón Gómez Sandoval, Guadalajara, Jaisco, Mexico

A Pharmacokinetic Study of Intravenous NTM-001 in Healthy Chinese Subjects

Phase 1
Completed
Conditions
Healthy Volunteers
Interventions
Drug: Ketorolac Tromethamine
First Posted Date
2022-05-19
Last Posted Date
2023-03-31
Lead Sponsor
Nuance Pharma (shanghai) Co., Ltd
Target Recruit Count
16
Registration Number
NCT05382546
Locations
🇨🇳

HUK Phase 1 clinical trials center, Hong Kong, Hong Kong, China

A Feasibility Study of Ketorolac Treatment for Cachexia in Patients With Advanced Pancreatic Ductal Adenocarcinoma

First Posted Date
2022-04-20
Last Posted Date
2024-06-27
Lead Sponsor
Andrew Hendifar, MD
Target Recruit Count
20
Registration Number
NCT05336266
Locations
🇺🇸

Cedars- Sinai Medical Center, Los Angeles, California, United States

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