Rocuronium
- Generic Name
- Rocuronium
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C32H53N2O4
- CAS Number
- 143558-00-3
- Unique Ingredient Identifier
- WRE554RFEZ
- Background
Rocuronium (rapid onset-curonium) is a desacetoxy analogue of vecuronium with a more rapid onset of action. It is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia, to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. Introduced in 1994, ro...
- Indication
For inpatients and outpatients as an adjunct to general anesthesia to facilitate both rapid sequence and routine tracheal intubation, and to provide skeletal muscle relaxation during surgery or mechanical ventilation.
- Associated Conditions
- Muscle fasciculation caused by succinylcholine
- Associated Therapies
- Curarization therapy, Neuromuscular blocking therapy, Facilitation of small bowel intubation therapy
Premedication for Non-Emergency Endotracheal Intubation In the NICU
- First Posted Date
- 2012-12-13
- Last Posted Date
- 2017-11-30
- Lead Sponsor
- Martin Espinosa, MD
- Target Recruit Count
- 45
- Registration Number
- NCT01749501
A Study Comparing the Use of Deep or Standard Neuromuscular Blockade in Combination With Low or Standard Insufflation Pressures in Participants Undergoing Laparoscopic Cholecystectomy (P07982)
- Conditions
- Interventions
- First Posted Date
- 2012-11-20
- Last Posted Date
- 2018-10-17
- Lead Sponsor
- Merck Sharp & Dohme LLC
- Target Recruit Count
- 127
- Registration Number
- NCT01728584
- Locations
- 🇩🇪
Merck Sharp & Dohme GmbH, Haar, Germany
🇮🇹MSD Italia S.r.l., Rome, Italy
Recovery After Laparoscopic Hysterectomy With Deep Neuromuscular Blockade and Low Intra-abdominal Pressure
- Conditions
- Interventions
- First Posted Date
- 2012-11-06
- Last Posted Date
- 2015-10-21
- Lead Sponsor
- Herlev Hospital
- Target Recruit Count
- 110
- Registration Number
- NCT01722097
- Locations
- 🇩🇰
Department of anesthesia and department of minimal invasive gynecology, Aleris-Hamlet, Søborg, Denmark
Skeletal Muscle Paralysis in Hypothermic Patients After Cardiac Arrest
- Conditions
- Interventions
- First Posted Date
- 2012-11-01
- Last Posted Date
- 2015-05-01
- Lead Sponsor
- Medical University of Vienna
- Target Recruit Count
- 60
- Registration Number
- NCT01719770
- Locations
- 🇦🇹
Medical University of Vienna, Department of Emergency Medicine, Vienna, Austria
A Study of Residual Curarization Incidence in China
- First Posted Date
- 2012-09-21
- Last Posted Date
- 2013-05-24
- Lead Sponsor
- Peking University First Hospital
- Target Recruit Count
- 6090
- Registration Number
- NCT01690338
- Locations
- 🇨🇳
Tongji Hospital, Tongji Medical College of HUST, Wuhan, Hubei, China
🇨🇳The Second Xiangya Hospital of Central South University, Changsha, Hunan, China
🇨🇳Xiangya Hospital of Central South University, Changsha, Hunan, China
Influence of Skeletal Muscle Paralysis on Metabolism in Hypothermic Patients After Cardiac Arrest
- Conditions
- Interventions
- First Posted Date
- 2012-09-11
- Last Posted Date
- 2017-08-29
- Lead Sponsor
- Medical University of Vienna
- Target Recruit Count
- 43
- Registration Number
- NCT01683006
- Locations
- 🇦🇹
Medical University Vienna, Vienna, Austria
Effect of Rocuronium on the Acute Hypoxic Ventilatory Response in Patients With Obstructive Sleep Apnea
- Conditions
- Interventions
- First Posted Date
- 2012-08-27
- Last Posted Date
- 2016-02-29
- Lead Sponsor
- Malin Jonsson Fagerlund
- Target Recruit Count
- 11
- Registration Number
- NCT01672606
- Locations
- 🇸🇪
Department of Anesthesiology, Surgical Sciences and Intensive Care Medicine, Karolinska University Hospital, Stockholm, Sweden
Comparison Between Cisatracurium and Rocuronium in Terms of Recovery of the Muscular Strength in the Postoperative Phase After Surgery and General Anaesthesia
- Conditions
- Interventions
- First Posted Date
- 2012-07-27
- Last Posted Date
- 2014-03-11
- Lead Sponsor
- Azienda Ospedaliera di Padova
- Target Recruit Count
- 120
- Registration Number
- NCT01651572
- Locations
- 🇮🇹
Azienda Ospedaliera di Padova, Padova, Italy
Laryngeal Injuries After Anesthesia Induction With Sevoflurane and After Anesthesia Induction With Rocuronium
- First Posted Date
- 2012-05-03
- Last Posted Date
- 2013-02-15
- Lead Sponsor
- University of Rostock
- Target Recruit Count
- 60
- Registration Number
- NCT01591031
- Locations
- 🇩🇪
University of Rostock, Rostock, Mecklenburg/Vorpommern, Germany
Succinylcholine or Rocuronium for Rigid Bronchoscopy Under General Anesthesia
- First Posted Date
- 2012-04-18
- Last Posted Date
- 2016-11-03
- Lead Sponsor
- Hopital Foch
- Target Recruit Count
- 6
- Registration Number
- NCT01579864
- Locations
- 🇫🇷
Hopital Foch, Suresnes, Ile de France, France
Drug Development Updates
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