Ketamine
- Generic Name
- Ketamine
- Brand Names
- Ketalar
- Drug Type
- Small Molecule
- Chemical Formula
- C13H16ClNO
- CAS Number
- 6740-88-1
- Unique Ingredient Identifier
- 690G0D6V8H
- Background
Ketamine is an NMDA receptor antagonist with a potent anesthetic effect. It was developed in 1963 as a replacement for phencyclidine (PCP) by Calvin Stevens at Parke Davis Laboratories. It started being used for veterinary purposes in Belgium and in 1964 was proven that compared to PCP, it produced minor hallucinogenic effects and shorter psychotomimetic eff...
- Indication
Ketamine is indicated as an anesthetic agent for recommended diagnostic and surgical procedures. If skeletal muscle relaxation is needed, it should be combined with a muscle relaxant. If the surgical procedure involves visceral pain, it should be supplemented with an agent that obtunds visceral pain. Ketamine can be used for induction of anesthesia prior oth...
- Associated Conditions
- -
- Associated Therapies
- General Anesthesia, Induction and Maintenance of General Anesthesia
Ketamine for Low Mood States in the ER
- First Posted Date
- 2010-09-27
- Last Posted Date
- 2020-08-24
- Lead Sponsor
- Yale University
- Target Recruit Count
- 14
- Registration Number
- NCT01209845
- Locations
- 🇺🇸
Yale New Haven Hospital Emergency Department, New Haven, Connecticut, United States
The Effect of Peritonsillar Infiltration of Ketamine and Dexamethasone for Postoperative Pain Relief in Children Following Adenotonsillectomy
- Conditions
- Interventions
- First Posted Date
- 2010-09-10
- Last Posted Date
- 2013-05-07
- Lead Sponsor
- Qazvin University Of Medical Sciences
- Target Recruit Count
- 160
- Registration Number
- NCT01198210
- Locations
- 🇮🇷
Qazvin university of medical science, Qazvin, Iran, Islamic Republic of
Treatment Resistant Depression (Pilot)
- Conditions
- Interventions
- First Posted Date
- 2010-08-10
- Last Posted Date
- 2023-09-15
- Lead Sponsor
- Washington University School of Medicine
- Target Recruit Count
- 20
- Registration Number
- NCT01179009
- Locations
- 🇺🇸
Washington University School of Medicine, Saint Louis, Missouri, United States
Intranasal Ketamine Versus Intramuscular Ketamine for Procedural Sedation in Pediatric Patients
- First Posted Date
- 2010-07-27
- Last Posted Date
- 2017-07-02
- Lead Sponsor
- University of Iowa
- Target Recruit Count
- 3
- Registration Number
- NCT01170247
- Locations
- 🇺🇸
University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States
Fentanyl vs. Low-Dose Ketamine for the Relief of Moderate to Severe Pain in Aeromedical Patients
- First Posted Date
- 2010-07-23
- Last Posted Date
- 2012-06-04
- Lead Sponsor
- University of Utah
- Registration Number
- NCT01169025
- Locations
- 🇺🇸
University of Utah Medical Center, Salt Lake City, Utah, United States
Analgesia During Pediatric Digestive Endoscopy: a Comparison of Two Protocols for Procedural Sedation
- First Posted Date
- 2010-07-23
- Last Posted Date
- 2014-12-04
- Lead Sponsor
- Université de Montréal
- Target Recruit Count
- 90
- Registration Number
- NCT01168492
- Locations
- 🇨🇦
Sainte Justine Hospital, Montreal, Quebec, Canada
The Effect of Ketamine on Attentiveness
- First Posted Date
- 2010-07-19
- Last Posted Date
- 2010-08-06
- Target Recruit Count
- 24
- Registration Number
- NCT01165294
Efficacity, Safety and Cost of Intravenous Morphine Titration Alone or Combined to Ketamine
- First Posted Date
- 2010-06-17
- Last Posted Date
- 2010-06-17
- Lead Sponsor
- Assistance Publique - Hôpitaux de Paris
- Target Recruit Count
- 160
- Registration Number
- NCT01146145
- Locations
- 🇫🇷
Hopital Louis Mourier, Colombes, France
Effects of Ketamine and Risperidone on Cognition
- Conditions
- Interventions
- First Posted Date
- 2010-06-09
- Last Posted Date
- 2016-11-09
- Lead Sponsor
- University of Manchester
- Target Recruit Count
- 87
- Registration Number
- NCT01140620
- Locations
- 🇬🇧
School of Psychology, University of Cardiff, Cardiff, United Kingdom
🇬🇧Institute of Psychiatry, King's College London, London, Greater London, United Kingdom
🇬🇧University of Manchester (Dept of Neuropyschiatry), Manchester, United Kingdom
Study of Depression-Ketamine-Brain Function
- First Posted Date
- 2010-06-03
- Last Posted Date
- 2015-12-07
- Lead Sponsor
- Markus KOSEL
- Target Recruit Count
- 10
- Registration Number
- NCT01135758
- Locations
- 🇨🇭
Service de Psychiatrie Adulte, Programme dépression, Geneva, Switzerland
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.