Ketamine
- Generic Name
- Ketamine
- Brand Names
- Ketalar
- Drug Type
- Small Molecule
- Chemical Formula
- C13H16ClNO
- CAS Number
- 6740-88-1
- Unique Ingredient Identifier
- 690G0D6V8H
- Background
Ketamine is an NMDA receptor antagonist with a potent anesthetic effect. It was developed in 1963 as a replacement for phencyclidine (PCP) by Calvin Stevens at Parke Davis Laboratories. It started being used for veterinary purposes in Belgium and in 1964 was proven that compared to PCP, it produced minor hallucinogenic effects and shorter psychotomimetic eff...
- Indication
Ketamine is indicated as an anesthetic agent for recommended diagnostic and surgical procedures. If skeletal muscle relaxation is needed, it should be combined with a muscle relaxant. If the surgical procedure involves visceral pain, it should be supplemented with an agent that obtunds visceral pain. Ketamine can be used for induction of anesthesia prior oth...
- Associated Conditions
- -
- Associated Therapies
- General Anesthesia, Induction and Maintenance of General Anesthesia
Competition With Striatal [11C]ORM-13070 Binding by Atipamezole and Endogenous Noradrenaline
- Conditions
- Interventions
- First Posted Date
- 2011-09-16
- Last Posted Date
- 2013-02-18
- Lead Sponsor
- University of Turku
- Target Recruit Count
- 10
- Registration Number
- NCT01435213
- Locations
- 🇫🇮
University of Turku, Clinical Research Services Turku CRST, Turku, Finland
🇫🇮University of Turku, Turku PET Centre, Turku, Finland
Evaluation of the Analgesic Effect of Midazolam and Ketamine as an Additive to Intrathecal Bupivacaine in Patients Undergoing Cesarean Section
- Conditions
- Interventions
- First Posted Date
- 2011-07-28
- Last Posted Date
- 2012-05-17
- Lead Sponsor
- Qazvin University Of Medical Sciences
- Target Recruit Count
- 90
- Registration Number
- NCT01404442
- Locations
- 🇮🇷
Qazvin university of medical science, Qazvin, Iran, Islamic Republic of
Effect of Ketamine Added to Intravenous Patient-controlled Analgesia on Postoperative Pain, Nausea and Vomiting in Patients Undergoing Lumbar Spinal Surgery
- First Posted Date
- 2011-07-14
- Last Posted Date
- 2014-03-05
- Lead Sponsor
- Yonsei University
- Target Recruit Count
- 50
- Registration Number
- NCT01394406
- Locations
- 🇰🇷
Severance Hospital, Seoul, Korea, Republic of
Ketamine Versus Co-administration of Ketamine and Propofol for Procedural Sedation in a Pediatric Emergency Department
- Conditions
- Interventions
- First Posted Date
- 2011-07-04
- Last Posted Date
- 2017-12-08
- Lead Sponsor
- University of Colorado, Denver
- Target Recruit Count
- 183
- Registration Number
- NCT01387139
- Locations
- 🇺🇸
Children's Hospital Colorado, Aurora, Colorado, United States
A Comparison of Etomidate and Ketamine for Anesthesia Induction in Coronary Artery Bypass Graft Surgery
- First Posted Date
- 2011-07-01
- Last Posted Date
- 2011-07-01
- Lead Sponsor
- Baskent University
- Target Recruit Count
- 40
- Registration Number
- NCT01386229
- Locations
- 🇹🇷
Baskent University, Faculty of Medicine, Ankara, Çankaya, Turkey
Intravenous Ketamine in the Treatment of Obsessive-Compulsive Disorder
- First Posted Date
- 2011-06-10
- Last Posted Date
- 2018-01-18
- Lead Sponsor
- Wayne Goodman MD
- Target Recruit Count
- 3
- Registration Number
- NCT01371110
- Locations
- 🇺🇸
Clinical Research Centers at Icahn School of Medicine at Mount Sinai, New York, New York, United States
Oral Ketamine for Control of Chronic Pain in Children
- First Posted Date
- 2011-06-09
- Last Posted Date
- 2013-02-15
- Lead Sponsor
- University of Rochester
- Target Recruit Count
- 12
- Registration Number
- NCT01369680
- Locations
- 🇺🇸
University of Rochester, Rochester, New York, United States
Ketamine Anesthesia in Electroconvulsive Therapy
- First Posted Date
- 2011-06-06
- Last Posted Date
- 2013-08-08
- Lead Sponsor
- Mayo Clinic
- Target Recruit Count
- 38
- Registration Number
- NCT01367119
- Locations
- 🇺🇸
Mayo Clinic in Rochester, Rochester, Minnesota, United States
Ketamine Infusion for Obsessive-Compulsive Disorder
- First Posted Date
- 2011-05-06
- Last Posted Date
- 2014-06-09
- Lead Sponsor
- Yale University
- Target Recruit Count
- 10
- Registration Number
- NCT01349231
- Locations
- 🇺🇸
Connecticut Mental Health Center/ YNHH, New Haven, Connecticut, United States
The Effect of Ketamine on Production of Inflammatory Markers in Post Operative Patients in Mulago Hospital
- First Posted Date
- 2011-04-20
- Last Posted Date
- 2011-04-20
- Lead Sponsor
- Makerere University
- Target Recruit Count
- 30
- Registration Number
- NCT01339065
- Locations
- 🇺🇬
Mulago Hospital National Refferal, surgical wards, Kampala, Uganda
Drug Development Updates
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