Sodium bicarbonate
- Generic Name
- Sodium bicarbonate
- Brand Names
- Alka-seltzer, Alka-seltzer Fruit Chews, Alka-seltzer Heartburn Relief, Bi-peglyte, Bibag, Bicart, Bss Ophthalmic Solution, Ceo-two, Colyte, Gavilyte-C, Gavilyte-G, Gavilyte-H and Bisacodyl, Gavilyte-N, Golytely, H.E.L.P.bicel, Hema Bp-38, Hemacart, Konvomep, Nulytely, Peglyte, Phoxillum, Physioneal 40, Prismasol, Zegerid, Zegerid Reformulated Aug 2006, Zegerid With Magnesium Hydroxide
- Drug Type
- Small Molecule
- Chemical Formula
- CHNaO3
- CAS Number
- 144-55-8
- Unique Ingredient Identifier
- 8MDF5V39QO
- Background
Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.
- Indication
Sodium bicarbonate is used for the treatment of metabolic acidosis which may occur in severe renal disease, uncontrolled diabetes, circulatory insufficiency due to shock or severe dehydration, extracorporeal circulation of blood, cardiac arrest and severe primary lactic acidosis. Also is indicated in severe diarrhea which is often accompanied by a significan...
- Associated Conditions
- Barbiturate intoxication, Breast Cancer, Constipation, Dental Decay, Duodenal Ulcer, Dyspepsia, Gastro-esophageal Reflux Disease (GERD), Gingival Bleeding, Heartburn, Helicobacter Infections, Hyperkalemia, Ischaemia, Metabolic Acidosis, Myocardial Infarction, Plaque, Dental, Pruritis of the skin, Skin Irritation, Upper GI Bleeding, Upset stomach, Zollinger-Ellison Syndrome, Abdominal bloating, Benign, active Gastric Ulcer, Methyl alcohol poisoning, Prophylaxis of Contrast-induced nephropathy, Salicylate poisoning, Severe Diarrhea, Swelling of the gums
- Associated Therapies
- Bowel preparation therapy
Comparison Between Effect of Acetazolamide and NaHco3 in Prevention of Contrast Nephropathy
- Conditions
- Interventions
- First Posted Date
- 2008-03-13
- Last Posted Date
- 2008-03-13
- Lead Sponsor
- Shiraz University of Medical Sciences
- Target Recruit Count
- 240
- Registration Number
- NCT00634491
- Locations
- 🇮🇷
Fars Heart Foundation , Kowsar hospital, Shiraz, Iran, Islamic Republic of
Sodium Bicarbonate Versus Saline for the Prevention of Contrast-induced Nephropathy
- Conditions
- Interventions
- First Posted Date
- 2008-02-05
- Last Posted Date
- 2012-05-08
- Lead Sponsor
- Ospedale Misericordia e Dolce
- Target Recruit Count
- 500
- Registration Number
- NCT00606827
- Locations
- 🇮🇹
Ospedale Misericordia e Dolce, Prato, Italy
A Prospective, Randomized TrialComparing Oral N-Acetylcysteine and Intravenous Sodium Bicarbonate
- Conditions
- Interventions
- First Posted Date
- 2007-12-24
- Last Posted Date
- 2023-09-21
- Lead Sponsor
- University of Nebraska
- Target Recruit Count
- 41
- Registration Number
- NCT00579995
- Locations
- 🇺🇸
Unversity of Nebraska Medical Center, Omaha, Nebraska, United States
Prevention of Contrast Induced Nephropathy in Oncology Patients With Sodium Bicarbonate
- Conditions
- Interventions
- First Posted Date
- 2007-10-08
- Last Posted Date
- 2014-03-03
- Lead Sponsor
- Barretos Cancer Hospital
- Target Recruit Count
- 27
- Registration Number
- NCT00540904
- Locations
- 🇧🇷
Hospital do Cancer de Barretos - Fundação PIO XII, Barretos, São Paulo, Brazil
Preventing Acute Renal Failure After Cardiac Surgery in High Risk Patients Using Sodium Bicarbonate Therapy
- First Posted Date
- 2007-08-30
- Last Posted Date
- 2012-10-24
- Lead Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
- Target Recruit Count
- 200
- Registration Number
- NCT00522756
- Locations
- 🇨🇦
McGill University Health Centre - Royal Victoria Hospital, Montreal, Quebec, Canada
Preventing Contrast Nephropathy With Sodium Bicarbonate in Patients With Pulmonary Edema,Heart Failure,Uncontrolled HTN
- First Posted Date
- 2007-08-09
- Last Posted Date
- 2008-11-26
- Lead Sponsor
- Tehran University of Medical Sciences
- Target Recruit Count
- 72
- Registration Number
- NCT00513825
- Locations
- 🇮🇷
Tehran Heart Center, Tehran, Iran, Islamic Republic of
COmbined N-acetylcysteine and Bicarbonate in PCI To Reduce Adverse Side Effect of contrasT
- Conditions
- Interventions
- First Posted Date
- 2007-07-06
- Last Posted Date
- 2014-01-14
- Lead Sponsor
- National University Hospital, Singapore
- Target Recruit Count
- 477
- Registration Number
- NCT00497328
- Locations
- 🇸🇬
The Heart Institute, Singapore, Singapore
The Use of Sodium Bicarbonate in the Prevention of Contrast Induced Nephropathy
- Conditions
- First Posted Date
- 2007-07-02
- Last Posted Date
- 2009-01-28
- Lead Sponsor
- Lenox Hill Hospital
- Target Recruit Count
- 468
- Registration Number
- NCT00494637
Use of Bicarbonate to Reduce the Incidence of Acute Renal Failure After Cardiac Surgery
- Conditions
- Interventions
- First Posted Date
- 2007-06-08
- Last Posted Date
- 2018-10-16
- Lead Sponsor
- Wake Forest University Health Sciences
- Target Recruit Count
- 123
- Registration Number
- NCT00484354
- Locations
- 🇺🇸
Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States
Clinical Trial of Sodium Bicarbonate to Prevent Contrast-Induced Nephropathy
- Conditions
- First Posted Date
- 2007-01-19
- Last Posted Date
- 2007-01-19
- Lead Sponsor
- Instituto Nacional de Cardiologia Ignacio Chavez
- Target Recruit Count
- 100
- Registration Number
- NCT00424320
- Locations
- 🇲🇽
ABC Medical Center, Mexico City, Mexico City (D.F.), Mexico
🇲🇽Ignacio Chávez National Institute of Cardiology, Mexico City, Mexico City (D.F:), Mexico
Drug Development Updates
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