Remifentanil

Generic Name
Remifentanil
Brand Names
Ultiva
Drug Type
Small Molecule
Chemical Formula
C20H28N2O5
CAS Number
132875-61-7
Unique Ingredient Identifier
P10582JYYK
Background

Remifentanil (marketed by Abbott as Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and adjunctive to an anaesthetic. Remifentanil is a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and causes respiratory depression and analgesia.

Indication

For use during the induction and maintenance of general anesthesia.

Associated Conditions
-
Associated Therapies
Immediate postoperative analgesia therapy, Induction and Maintenance of General Anesthesia, Monitored anesthesia care sedation

Effect of Dexmedetomidine Combined With Low-dose Nalmefene on Preventing Remifentanil-induced Postoperative Hyperalgesia

First Posted Date
2017-03-30
Last Posted Date
2021-08-03
Lead Sponsor
Tianjin Medical University General Hospital
Target Recruit Count
150
Registration Number
NCT03096730
Locations
๐Ÿ‡จ๐Ÿ‡ณ

Tianjin Medical University General Hospital, Tianjin, Tianjin, China

A Study to Compare the Long-term Outcomes After Two Different Anaesthetics

First Posted Date
2017-03-24
Last Posted Date
2024-07-05
Lead Sponsor
Murdoch Childrens Research Institute
Target Recruit Count
450
Registration Number
NCT03089905
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Boston Children's Hospital, Boston, Massachusetts, United States

๐Ÿ‡บ๐Ÿ‡ธ

The University of Texas Southwestern Medical Center, Dallas, Texas, United States

๐Ÿ‡บ๐Ÿ‡ธ

Cleveland Clinic, Cleveland, Ohio, United States

and more 18 locations

Effect of Ultra-low Dose Naloxone on Remifentanil-Induced Hyperalgesia

First Posted Date
2017-02-28
Last Posted Date
2024-08-23
Lead Sponsor
University of California, Irvine
Target Recruit Count
105
Registration Number
NCT03066739
Locations
๐Ÿ‡บ๐Ÿ‡ธ

UC Irvine Medical Center, Orange, California, United States

Determination of Remifentanil's ED50 for Rapid Sequence Intubation Avoiding Bradycardia and Hypotension in Adults

Phase 3
Completed
Conditions
Interventions
First Posted Date
2017-02-27
Last Posted Date
2017-09-13
Lead Sponsor
Brasilia University Hospital
Target Recruit Count
15
Registration Number
NCT03065309
Locations
๐Ÿ‡ง๐Ÿ‡ท

Hospital das Forรงas Armadas, Brasilia, Distrito Federal, Brazil

Evaluating Pain Outcomes of Caudal vs Ilioinguinal Nerve Block in Children Undergoing Hernia Repair

First Posted Date
2017-02-03
Last Posted Date
2017-11-14
Lead Sponsor
Alberta Children's Hospital
Target Recruit Count
88
Registration Number
NCT03041948
Locations
๐Ÿ‡จ๐Ÿ‡ฆ

Alberta Children's Hospital, Calgary, Alberta, Canada

๐Ÿ‡จ๐Ÿ‡ฆ

Royal University Hospital/University of Saskatchewan, Saskatoon, Saskatchewan, Canada

Comparison of Remifentanil as a Sole Agent or in Combination With Midazolam Versus Fentanyl/Midazolam During Sedation for Colonoscopy

First Posted Date
2017-01-31
Last Posted Date
2019-10-23
Lead Sponsor
King Hamad University Hospital, Bahrain
Target Recruit Count
75
Registration Number
NCT03037892
Locations
๐Ÿ‡ง๐Ÿ‡ญ

Awali Hospital, Manama, Bahrain

Anaesthesia for Laparoscopic Sleeve Gastrectomy

First Posted Date
2017-01-24
Last Posted Date
2020-09-16
Lead Sponsor
Menoufia University
Target Recruit Count
100
Registration Number
NCT03029715

Intraoperative Methadone Administration for Improved Pain Control in Spinal Fusion Patients

First Posted Date
2016-12-12
Last Posted Date
2023-05-22
Lead Sponsor
Montefiore Medical Center
Target Recruit Count
10
Registration Number
NCT02989597
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Montefiore Medical Center, Bronx, New York, United States

Conscious Sedation for Epilepsy Surgery

First Posted Date
2016-12-09
Last Posted Date
2020-10-09
Lead Sponsor
Menoufia University
Target Recruit Count
60
Registration Number
NCT02988050
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