Midazolam

Generic Name
Midazolam
Brand Names
Buccolam, Busulfex, Nayzilam, Seizalam
Drug Type
Small Molecule
Chemical Formula
C18H13ClFN3
CAS Number
59467-70-8
Unique Ingredient Identifier
R60L0SM5BC
Background

Midazolam is a short-acting hypnotic-sedative drug with anxiolytic, muscle relaxant, anticonvulsant, sedative, hypnotic, and amnesic properties. It belongs to a class of drugs called benzodiazepines. This drug is unique from others in this class due to its rapid onset of effects and short duration of action. Midazolam is available by oral, rectal, intranasal...

Indication

Midazolam has different indications depending on its formulation by the FDA.

Nasal
...

Associated Conditions
Epileptic seizure, Status Epilepticus
Associated Therapies
Anaesthesia, Anxiolytic therapy therapy, Sedation for mechanically-ventilated patients, Preoperative amnesia therapy, Preoperative sedation therapy
Clinical Trials
Related News

Study of Cobimetinib in Participants With Solid Tumors

First Posted Date
2007-05-01
Last Posted Date
2016-08-26
Lead Sponsor
Genentech, Inc.
Target Recruit Count
119
Registration Number
NCT00467779

The Effect of Etomidate on Patient Outcomes After Single Bolus Doses

Not Applicable
Completed
Conditions
Sepsis
Trauma
Interventions
Drug: Etomidate
Drug: midazolam
First Posted Date
2007-03-01
Last Posted Date
2012-04-11
Lead Sponsor
Advocate Hospital System
Target Recruit Count
122
Registration Number
NCT00441792
Locations
🇺🇸

Advocate Christ Medical Center, Oak Lawn, Illinois, United States

Anesthesia in Flexible Bronchoscopy for Lung Cancer Diagnostic

Phase 4
Completed
Conditions
Lung Cancer
First Posted Date
2007-02-27
Last Posted Date
2007-02-27
Lead Sponsor
Hospital Pompeia
Registration Number
NCT00440960
Locations
🇧🇷

Hospital Pompeia, Caxias do Sul, RS, Brazil

🇧🇷

Hospital Medianeira, Caxias do Sul, RS, Brazil

🇧🇷

General Hospital of Universidade de Caxias do Sul, Caxias do Sul, RS, Brazil

An Investigation To Determine The Potential Interaction Effect Between GW876008 And Midazolam.

Phase 1
Completed
Conditions
Healthy Subjects
First Posted Date
2007-01-18
Last Posted Date
2009-05-18
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
25
Registration Number
NCT00423761
Locations
🇺🇸

GSK Investigational Site, Dallas, Texas, United States

Is Dexmedetomidine Associated With a Lower Incidence of Postoperative Delirium When Compared to Propofol or Midazolam in Cardiac Surgery Patients

First Posted Date
2007-01-04
Last Posted Date
2022-05-27
Lead Sponsor
Stanford University
Target Recruit Count
90
Registration Number
NCT00417664
Locations
🇺🇸

Stanford University Medical Center, Stanford, California, United States

Efficacy of Sublingual Midazolam in Association With Oral Morphine in Children Analgesia After Bone Fracture

Phase 3
Completed
Conditions
Fractures
Interventions
Drug: Midazolam
Drug: Placebo
First Posted Date
2006-12-27
Last Posted Date
2013-08-28
Lead Sponsor
Assistance Publique - Hôpitaux de Paris
Target Recruit Count
60
Registration Number
NCT00416039
Locations
🇫🇷

Hopital Necker enfants Malade - Department of Pediatric Emergency, Paris, France

HCV-796 and Midazolam Drug Interaction Study in Healthy Subjects

Phase 1
Completed
Conditions
Healthy
First Posted Date
2006-12-12
Last Posted Date
2007-12-05
Lead Sponsor
Wyeth is now a wholly owned subsidiary of Pfizer
Target Recruit Count
38
Registration Number
NCT00410254

Anaesthesia With Propofol Versus Midazolam : Effect on Oxidative Stress in the Brain of Head Trauma Patients

Phase 3
Terminated
Conditions
Traumatic Brain Injury
Interventions
Drug: Midazolam
Drug: Propofol
First Posted Date
2006-06-14
Last Posted Date
2012-03-02
Lead Sponsor
Rennes University Hospital
Target Recruit Count
30
Registration Number
NCT00336882
Locations
🇫🇷

Réanimation Chirurgicale - Hôpital de Pontchaillou, Rennes, France

Effect of Dexmedetomidine Upon Sleep Postoperatively

Phase 4
Withdrawn
Conditions
Sleep
First Posted Date
2006-06-06
Last Posted Date
2014-07-14
Lead Sponsor
Duke University
Registration Number
NCT00333632
Locations
🇺🇸

Duke University Medical Center, Durham, North Carolina, United States

Intranasal Midazolam Versus Rectal Diazepam for Treatment of Seizures

Phase 2
Completed
Conditions
Seizures
Interventions
Drug: Midazolam
Drug: Diazepam
First Posted Date
2006-05-17
Last Posted Date
2011-10-26
Lead Sponsor
University of Utah
Target Recruit Count
358
Registration Number
NCT00326612
Locations
🇺🇸

Primary Children's Medical Center, Salt Lake City, Utah, United States

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