Propofol
- Generic Name
- Propofol
- Brand Names
- Diprivan
- Drug Type
- Small Molecule
- Chemical Formula
- C12H18O
- CAS Number
- 2078-54-8
- Unique Ingredient Identifier
- YI7VU623SF
- Background
Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. drowsiness, nausea, vomiting) than with thiopental, methohexital, and etomidate. Propofol may be used prior to diagnostic procedures requiring anaesthesia, in the management of refractory status epilepticus, and for induction and/or maintenance of anaesthesia prior to and during surgeries.
- Indication
Used for induction and/or maintenance of anaesthesia and for management of refractory status epilepticus.
- Associated Conditions
- -
- Associated Therapies
- Induction of anesthesia therapy, Maintenance of anesthesia therapy, Monitored anesthesia care sedation, Sedative therapy
Step 2 of A Two-step Trial to Evaluate the Effectiveness and Safety of Remimazolam Besylate for Sedation in ICU Patients
- Conditions
- Interventions
- First Posted Date
- 2023-03-24
- Last Posted Date
- 2024-01-31
- Lead Sponsor
- Wuhan Union Hospital, China
- Target Recruit Count
- 164
- Registration Number
- NCT05782894
- Locations
- 🇨🇳
Wuhan Union Hospital, Wuhan, Hubei, China
Effect of Bispectral Index Monitoring (BIS) on Body Movement of Outpatients Undergoing Gastroscopy
- Conditions
- Interventions
- First Posted Date
- 2023-03-17
- Last Posted Date
- 2023-03-17
- Lead Sponsor
- West China Hospital
- Target Recruit Count
- 400
- Registration Number
- NCT05773807
- Locations
- 🇨🇳
West China Hospital, Chengdu, Sichuan, China
Effects of Propofol on Respiratory Adverse Events During Extubation in Children Undergoing Tonsil Adenoidectomy
- Conditions
- Interventions
- First Posted Date
- 2023-03-15
- Last Posted Date
- 2024-02-05
- Lead Sponsor
- Children's Hospital of Fudan University
- Target Recruit Count
- 239
- Registration Number
- NCT05769842
- Locations
- 🇨🇳
Children's Hospital affiliated with Fudan University, Shanghai, China
Prevention of Post-Operative Nausea and Vomiting With Propofol Infusion
- Conditions
- Interventions
- First Posted Date
- 2023-03-08
- Last Posted Date
- 2024-03-28
- Lead Sponsor
- Milton S. Hershey Medical Center
- Target Recruit Count
- 150
- Registration Number
- NCT05759481
- Locations
- 🇺🇸
Penn State Health Milton S Hershey Medical Center, Hershey, Pennsylvania, United States
Electroencephalogram Based Real-Time Sedation Level Prediction
- Conditions
- First Posted Date
- 2023-03-07
- Last Posted Date
- 2023-03-13
- Lead Sponsor
- University Medical Center Groningen
- Target Recruit Count
- 1000
- Registration Number
- NCT05757622
Comparison of Esketamine-Propofol and Fentanyl-Propofol
- Conditions
- Interventions
- First Posted Date
- 2023-03-02
- Last Posted Date
- 2023-08-15
- Lead Sponsor
- Eye & ENT Hospital of Fudan University
- Target Recruit Count
- 120
- Registration Number
- NCT05752409
- Locations
- 🇨🇳
Anesthesiology Department of Affiliated Eye and ENT Hospital, Fudan University, Shanghai, Shanghai, China
Dose Systemic Lidocaine Improve the Quality of Recovery After Colorectal Endoscopic Submucosal Dissection
- Conditions
- Interventions
- First Posted Date
- 2023-03-01
- Last Posted Date
- 2024-05-10
- Lead Sponsor
- Fujian Provincial Hospital
- Target Recruit Count
- 234
- Registration Number
- NCT05750056
- Locations
- 🇨🇳
Fujian provincial hospital, Fuzhou, Fujian, China
Effect of Anesthetics on Troponin I and С-reactive Protein
- Conditions
- Interventions
- First Posted Date
- 2023-02-24
- Last Posted Date
- 2023-06-05
- Lead Sponsor
- Astana Medical University
- Target Recruit Count
- 255
- Registration Number
- NCT05742789
- Locations
- 🇰🇿
Bekzat, Astana, Kazakhstan
Propofol Sedation vs. Anaesthetist Guided Anaesthesia in Oocyte Pickup
- First Posted Date
- 2023-02-23
- Last Posted Date
- 2024-05-14
- Lead Sponsor
- Wunschbaby Institut Feichtinger
- Target Recruit Count
- 100
- Registration Number
- NCT05741814
- Locations
- 🇦🇹
Wunschbaby Institut Feichtinger, Vienna, Austria
REmimazolam vs Propofol Total Intravenous Anesthesia on Outcomes After Major Noncardiac SurgEry
- Conditions
- Interventions
- First Posted Date
- 2023-02-15
- Last Posted Date
- 2023-04-07
- Lead Sponsor
- Nanfang Hospital, Southern Medical University
- Target Recruit Count
- 7188
- Registration Number
- NCT05728775
- Locations
- 🇨🇳
Beijing Chaoyang Hospital, Capital Medical University, Beijing, Beijing, China
🇨🇳Southern Medical University Nanfang Hospital, Guangzhou, Guangdong, China
🇨🇳The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China
Drug Development Updates
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