Propofol

Generic Name: Propofol

Brand Names: Diprivan

Drug Type: Small Molecule

Chemical Formula: C_₁₂H_₁₈O

CAS Number: 2078-54-8

Unique Ingredient Identifier: YI7VU623SF

Background: Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. ...

Indication: Used for induction and/or maintenance of anaesthesia and for management of refractory status epilepticus.

Associated Conditions: -

Associated Therapies: Induction of anesthesia therapy, Maintenance of anesthesia therapy, Monitored anesthesia care sedation, Sedative therapy

Clinical Trials

Dexmedetomidinine in the Prevention of Postoperative Delirium in the Intensive Care Unit After Cardiac Surgery

Phase 3

Recruiting

Conditions: Intensive Care Unit Delirium

Interventions: Drug: Propofol
Drug: Dexmedetomidine

First Posted Date: 2023-05-09

Last Posted Date: 2024-12-04

Lead Sponsor: University of Novi Sad

Target Recruit Count: 200

Registration Number: NCT05849597

Locations: 🇷🇸
Institute of Cardiovascular Diseases of Vojvodina, Sremska Kamenica, Serbia

Comparison of Ciprofol-based and Propofol-based Total Intravenous Anesthesia on Postoperative Quality of Recovery

Not Applicable

Recruiting

Conditions: Hypnotics and Sedatives
Postoperative Recovery
Postoperative Complications
Anesthetics, Intravenous

Interventions: Drug: Ciprofol
Drug: Propofol

First Posted Date: 2023-05-06

Last Posted Date: 2024-04-09

Lead Sponsor: Xijing Hospital

Target Recruit Count: 280

Registration Number: NCT05843383

Locations: 🇨🇳
Xijing Hospital, Xi'an, Shaanxi, China

Total Intravenous Anesthesia for Rigid Bronchoscopy Using Remimazolam

Not Applicable

Not yet recruiting

Conditions: Endobronchial Mass
Respiratory Disease
Tracheal Stenosis

Interventions: Drug: Remimazolam besylate
Drug: Propofol

First Posted Date: 2023-04-28

Last Posted Date: 2023-04-28

Lead Sponsor: Samsung Medical Center

Target Recruit Count: 60

Registration Number: NCT05835713

Comparison of Postoperative Recovery of Sevoflurane and Propofol After Transsphenoidal Surgery

Phase 4

Recruiting

Conditions: Pituitary Adenoma

Interventions: Drug: sevoflurane
Drug: propofol

First Posted Date: 2023-04-21

Last Posted Date: 2024-05-01

Lead Sponsor: Peking Union Medical College Hospital

Target Recruit Count: 252

Registration Number: NCT05822817

Locations: 🇨🇳
Peking Union Medical College Hospital, Beijing, Beijing, China

The Safety of Etomidate - Propofol Mixture vs Propofol in Total Intravenous Anesthesia During Abdominal Surgery

Not Applicable

Recruiting

Conditions: Etomidate
Hypotension

Interventions: Drug: Etomidate - propofol mixture
Drug: Propofol

First Posted Date: 2023-04-12

Last Posted Date: 2024-02-23

Lead Sponsor: Ailin Luo

Target Recruit Count: 468

Registration Number: NCT05810363

Locations: 🇨🇳
Tongji hospital, Wuhan, China

Continuous Infusion of Remidazolam for Colonoscopic Polypectomy in Elderly Patients

Not Applicable

Completed

Conditions: Colon Disease

Interventions: Drug: Remimazolam
Drug: Propofol

First Posted Date: 2023-04-06

Last Posted Date: 2024-08-13

Lead Sponsor: Tongji Hospital

Target Recruit Count: 114

Registration Number: NCT05801757

Locations: 🇨🇳
Tongji Hospital, Wuhan, Hubei, China

Effect of Midazolam Bolus on Eleveld and Schnider TCI (Target Controlled Infusion) Models

Completed

Conditions: Propofol
Anesthesia Brain Monitoring

Interventions: Drug: Propofol

First Posted Date: 2023-04-05

Last Posted Date: 2023-10-19

Lead Sponsor: University of Padova

Target Recruit Count: 40

Registration Number: NCT05800288

Locations: 🇮🇹
ULSS2, Treviso, Italy

Development of a Pharmacodynamic Model for Propofol in Older Adults

Not Applicable

Not yet recruiting

Conditions: Aged

Interventions: Drug: Propofol

First Posted Date: 2023-03-30

Last Posted Date: 2024-06-04

Lead Sponsor: Pontificia Universidad Catolica de Chile

Target Recruit Count: 60

Registration Number: NCT05790720

Locations: 🇨🇱
Pontificia Universidad Católica de Chile, Santiago, Región Metropolitana, Chile

Evaluation of Equivalent Minimum Alveolar Concentration (eMAC) During Propofol/Remifentanil Anesthesia

Not Applicable

Completed

Conditions: General Anaesthesia

Interventions: Drug: Propofol
Drug: Low Remifentanil
Drug: Heigh Remifentanil
Procedure: tetanic electrical stimulation
Procedure: Intubation

First Posted Date: 2023-03-29

Last Posted Date: 2023-06-15

Lead Sponsor: Zhang Haopeng

Target Recruit Count: 62

Registration Number: NCT05789992

Locations: 🇨🇳
Xijing Hospital, Xian, Shaanxi, China

Effect of Desflurane on Pediatric Acute Respiratory Distress Syndrome After Living Donor Liver Transplant Recipients

Phase 4

Not yet recruiting

Conditions: Pediatric Acute Respiratory Distress Syndrome
Biliary Atresia
Desflurane

Interventions: Drug: propofol
Drug: desflurane

First Posted Date: 2023-03-24

Last Posted Date: 2023-03-24

Lead Sponsor: Tianjin First Central Hospital

Target Recruit Count: 165

Registration Number: NCT05783518

Locations: 🇨🇳
TianjinFCH, Tianjin, Tianjin, China

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