Propofol

Generic Name: Propofol

Brand Names: Diprivan

Drug Type: Small Molecule

Chemical Formula: C_₁₂H_₁₈O

CAS Number: 2078-54-8

Unique Ingredient Identifier: YI7VU623SF

Background: Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. ...

Indication: Used for induction and/or maintenance of anaesthesia and for management of refractory status epilepticus.

Associated Conditions: -

Associated Therapies: Induction of anesthesia therapy, Maintenance of anesthesia therapy, Monitored anesthesia care sedation, Sedative therapy

Clinical Trials

The Effect of Desflurane Versus Sevoflurane Versus Propofol on Postoperative Delirium

Phase 4

Recruiting

Conditions: Postoperative Delirium
Postoperative Cognitive Dysfunction
Major Noncardiac Surgery

Interventions: Drug: Desflurane
Drug: Sevoflurane
Drug: Propofol

First Posted Date: 2023-08-14

Last Posted Date: 2024-06-17

Lead Sponsor: Medical University of Vienna

Target Recruit Count: 1332

Registration Number: NCT05990790

Locations: 🇦🇹
Medical University of Innsbruck, Innsbruck, Austria
🇦🇹
Medical University of Vienna, Vienna, Austria

Performance Analysis of Hermetic Closed-loop Anesthesia Delivery System

Not Applicable

Recruiting

Conditions: Anesthesia

Interventions: Drug: Propofol

First Posted Date: 2023-08-01

Last Posted Date: 2024-12-02

Lead Sponsor: Sir Ganga Ram Hospital

Target Recruit Count: 100

Registration Number: NCT05967403

Locations: 🇮🇳
Nitin Sethi, New Delhi, Delhi, India

Esketamine and Propofol for Children With Autism Spectrum Disorder Undergoing Colonoscopy

Not Applicable

Completed

Conditions: Autism Spectrum Disorder

Interventions: Drug: Esketamine
Drug: Propofol

First Posted Date: 2023-07-19

Last Posted Date: 2023-10-10

Lead Sponsor: The Second Hospital of Nanjing Medical University

Target Recruit Count: 46

Registration Number: NCT05951465

Locations: 🇨🇳
Sir Run Run Hospital, Nanjing, Jiangsu, China

Cerebral Flow-metabolism Coupling During Adult Surgery

Phase 4

Recruiting

Conditions: Anesthesia

Interventions: Drug: Propofol
Drug: Sevoflurane
Drug: Phenylephrine
Drug: Ephedrine

First Posted Date: 2023-07-12

Last Posted Date: 2023-10-18

Lead Sponsor: Jason Chui

Target Recruit Count: 80

Registration Number: NCT05941494

Locations: 🇨🇦
London Health Sciences Centre, London, Ontario, Canada

Hemodynamic Responses of Dexmedetomidine, Lidocaine or Propofol Infusions During Laparoscopic Cholecystectomy

Phase 4

Recruiting

Conditions: Lidocaine
Propofol
Hemodynamic Responses
Laparoscopic Cholecystectomy
Dexmedetomidine

Interventions: Drug: normal saline
Drug: Lidocain
Drug: Dexmedetomidine
Drug: Propofol

First Posted Date: 2023-07-10

Last Posted Date: 2023-07-11

Lead Sponsor: Menoufia University

Target Recruit Count: 80

Registration Number: NCT05937282

Locations: 🇪🇬
Menoufia University, Shibīn Al Kawm, Menoufia, Egypt

The Effects of Using Different Anesthetics on the Prognosis of Primary Tumors and Its Mechanism of Action

Phase 4

Recruiting

Conditions: Lung Cancer
Liver Cancer
Ovarian Cancer
Brain Tumor

Interventions: Drug: Propofol
Drug: Sevoflurane

First Posted Date: 2023-07-03

Last Posted Date: 2023-09-28

Lead Sponsor: Kaohsiung Medical University Chung-Ho Memorial Hospital

Target Recruit Count: 1316

Registration Number: NCT05926336

Locations: 🇨🇳
Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung, Taiwan

Effects of Propofol on Brain Function in Patients With Parkinson's Disease

Recruiting

Conditions: PD - Parkinson's Disease

Interventions: Drug: Propofol

First Posted Date: 2023-06-08

Last Posted Date: 2023-06-27

Lead Sponsor: Beijing Tiantan Hospital

Target Recruit Count: 600

Registration Number: NCT05895019

Locations: 🇨🇳
Beijing Tiantan Hospital, Capital Medical University, Beijing, Beijing, China

Efficacy and Safety of Ciprofol for General Anaesthesia in Patients Undergoing Transcatheter Aortic Valve Replacement

Phase 4

Completed

Conditions: Hemodynamics
Transcatheter Aortic Valve Replacement
General Anesthesia
Post-induction Hypotension

Interventions: Drug: ciprofol
Drug: propofol

First Posted Date: 2023-05-31

Last Posted Date: 2024-10-14

Lead Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University

Target Recruit Count: 124

Registration Number: NCT05881291

Locations: 🇨🇳
The Second Affiliated Hospital of Zhejiang University anesthesiology department, Hangzhou, Zhejiang, China

Propofol Versus Dexmedetomidine on the Incidence of Postoperative Nausea and Vomiting

Not Applicable

Recruiting

Conditions: Nausea and Vomiting, Postoperative

Interventions: Drug: Propofol
Drug: Dexmedetomidine

First Posted Date: 2023-05-25

Last Posted Date: 2023-08-31

Lead Sponsor: Cairo University

Target Recruit Count: 45

Registration Number: NCT05875077

Locations: 🇪🇬
Kasralaini Medical School, Cairo, Egypt

Efficacy and Safety of Fospropofol Disodium Versus Propofol for Deep Sedation in Critically Ill Patients

Phase 2

Recruiting

Conditions: Critical Illness

Interventions: Drug: Fospropofol disodium for injection
Drug: Propofol

First Posted Date: 2023-05-23

Last Posted Date: 2023-07-05

Lead Sponsor: Xiaobo Yang, MD

Target Recruit Count: 60

Registration Number: NCT05870514

Locations: 🇨🇳
Wuhan Union Hospital, Wuhan, Hubei, China

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