Propofol

Generic Name
Propofol
Brand Names
Diprivan
Drug Type
Small Molecule
Chemical Formula
C12H18O
CAS Number
2078-54-8
Unique Ingredient Identifier
YI7VU623SF
Background

Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. drowsiness, nausea, vomiting) than with thiopental, methohexital, and etomidate. Propofol may be used prior to diagnostic procedures requiring anaesthesia, in the management of refractory status epilepticus, and for induction and/or maintenance of anaesthesia prior to and during surgeries.

Indication

Used for induction and/or maintenance of anaesthesia and for management of refractory status epilepticus.

Associated Conditions
-
Associated Therapies
Induction of anesthesia therapy, Maintenance of anesthesia therapy, Monitored anesthesia care sedation, Sedative therapy

Comparison of Remimazolam and Propofol Effect on Oxygenation Reservoir During Diagnostic Gastric Endoscopy

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2023-02-13
Last Posted Date
2023-12-08
Lead Sponsor
Yonsei University
Target Recruit Count
70
Registration Number
NCT05723627
Locations
🇰🇷

Yonsei University Health System, Severance Hospital, Seoul, Korea, Republic of

Effect of Gender on Propofol Requirement

Completed
Conditions
Interventions
First Posted Date
2023-02-13
Last Posted Date
2024-03-26
Lead Sponsor
Sir Ganga Ram Hospital
Target Recruit Count
80
Registration Number
NCT05725135
Locations
🇮🇳

Sir Ganga Ram Hospital, New Delhi, Delhi, India

Clinical Observation of Ciprofol for Anesthesia Induction

Phase 4
Not yet recruiting
Conditions
Interventions
First Posted Date
2023-01-31
Last Posted Date
2023-01-31
Lead Sponsor
Xiumei Song
Target Recruit Count
90
Registration Number
NCT05706337

The Effects of Sevoflurane, Isoflurane and Propofol During Cardiac Surgery

First Posted Date
2023-01-25
Last Posted Date
2023-01-25
Lead Sponsor
Astana Medical University
Target Recruit Count
89
Registration Number
NCT05695287
Locations
🇰🇿

Bekzat, Astana, Kazakhstan

Influence of Anesthetics on Clinical Outcome in Mitral and Aortic Valve Replacement in Adults

First Posted Date
2023-01-25
Last Posted Date
2023-01-25
Lead Sponsor
Astana Medical University
Target Recruit Count
75
Registration Number
NCT05696509
Locations
🇰🇿

Bekzat, Astana, Kazakhstan

Influence of Anesthetics on Clinical Outcome During Cardiac Surgery in Adults

First Posted Date
2023-01-23
Last Posted Date
2023-01-23
Lead Sponsor
Astana Medical University
Target Recruit Count
90
Registration Number
NCT05693428
Locations
🇰🇿

Bekzat, Astana, Kazakhstan

Comparison of Recovery Profiles Among Propofol, Remimazolam, and Dexmedetomidine After Intraoperative Sedation

First Posted Date
2023-01-18
Last Posted Date
2024-01-31
Lead Sponsor
Asan Medical Center
Target Recruit Count
120
Registration Number
NCT05688345
Locations
🇰🇷

Asan Medical Center, Seoul, Korea, Republic of

Remiazolam Combined With Esketamine in Painless Bidirectional Endoscopy in Children

First Posted Date
2023-01-17
Last Posted Date
2023-08-21
Lead Sponsor
Tongji Hospital
Target Recruit Count
106
Registration Number
NCT05686863
Locations
🇨🇳

Tongji Hospital, Wuhan, Hubei, China

The Effects of Using Different Anesthetics on the Prognosis of Primary Lung Tumors and Its Mechanism of Action

First Posted Date
2022-12-23
Last Posted Date
2023-05-30
Lead Sponsor
Kaohsiung Medical University Chung-Ho Memorial Hospital
Target Recruit Count
300
Registration Number
NCT05663242
Locations
🇨🇳

Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung, Taiwan

Effect of Ciprofol Infusion for Induction and Maintenance on Hemodynamics and Postoperative Recovery

First Posted Date
2022-12-23
Last Posted Date
2024-01-10
Lead Sponsor
Xiumei Song
Target Recruit Count
126
Registration Number
NCT05664386
Locations
🇨🇳

Department of Anesthesiology, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, Shandong, China

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