Propofol

Generic Name: Propofol

Brand Names: Diprivan

Drug Type: Small Molecule

Chemical Formula: C_₁₂H_₁₈O

CAS Number: 2078-54-8

Unique Ingredient Identifier: YI7VU623SF

Background: Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. drowsiness, nausea, vomiting) than with thiopental, methohexital, and etomidate. Propofol may be used prior to diagnostic procedures requiring anaesthesia, in the management of refractory status epilepticus, and for induction and/or maintenance of anaesthesia prior to and during surgeries.

Indication: Used for induction and/or maintenance of anaesthesia and for management of refractory status epilepticus.

Associated Conditions: -

Associated Therapies: Induction of anesthesia therapy, Maintenance of anesthesia therapy, Monitored anesthesia care sedation, Sedative therapy

Clinical Trials

Comparison of Propofol and Sevoflurane Anesthesia on the Quality of Recovery After Ambulatory Surgery in Obese Patients

Not Applicable

Withdrawn

Conditions: Quality of Recovery

Interventions: Drug: sevoflurane
Drug: Propofol

First Posted Date: 2022-09-07

Last Posted Date: 2022-09-07

Lead Sponsor: Jiangang Song

Registration Number: NCT05529875

Locations: 🇨🇳
Shuguang Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, Shanghai, China

The Application and Validation of Triple Drug Response Surface Models on Density Spectral Array in Clinical Anesthesia

Not yet recruiting

Conditions: Drug Interaction
Anesthesia; Functional
Anesthesia

Interventions: Device: Bispectral index (BIS) or Patient State Index (PSI)
Drug: Propofol
Drug: Alfentanil
Drug: Dexmedetomidine

First Posted Date: 2022-09-01

Last Posted Date: 2022-09-07

Lead Sponsor: Taipei Veterans General Hospital, Taiwan

Target Recruit Count: 60

Registration Number: NCT05525351

Locations: 🇨🇳
Taipei Veterans General Hospital, Taipei, Taiwan

Efficacy and Safety of Ciprofol in Laparoscopic Sleeve Gastrectomy

Phase 4

Completed

Conditions: Bariatric Surgery

Interventions: Drug: Ciprofol
Drug: Propofol

First Posted Date: 2022-08-31

Last Posted Date: 2024-08-28

Lead Sponsor: The Third People's Hospital of Chengdu

Target Recruit Count: 212

Registration Number: NCT05522998

Locations: 🇨🇳
The Third People's Hospital of Chengdu, Affiliated Hospital of Southwest Jiaotong University, Chengdu, Sichuan, China

Etomidate Induction in Hysteroscopic Surgery

Not Applicable

Conditions: Etomidate Induced Dose
Hysteroscopic Surgery

Interventions: Drug: etomidate
Drug: propofol

First Posted Date: 2022-08-30

Last Posted Date: 2022-08-30

Lead Sponsor: Peking University Third Hospital

Target Recruit Count: 200

Registration Number: NCT05520645

Hypoxia During Gastroenterological Endoscope Procedures Sedated With Ciprofol In Overweight Or Obesity Patients

Phase 4

Completed

Conditions: Gastric Ulcer
Gastric Cancer
Gastrointestinal Polyp

Interventions: Drug: Propofol
Drug: Ciprofol

First Posted Date: 2022-08-29

Last Posted Date: 2024-06-07

Lead Sponsor: RenJi Hospital

Target Recruit Count: 1090

Registration Number: NCT05518929

Locations: 🇨🇳
Dalian Municipal Friendship Hospital, Dalian, Liaoning, China
🇨🇳
Renji Hospital, Shanghai, Shanghai, China
🇨🇳
Beijing Hospital, Beijing, Beijing, China

and more 2 locations