Morphine
- Generic Name
- Morphine
- Brand Names
- Arymo, Avinza, Doloral, Duramorph, Embeda, Infumorph, Kadian, M-ediat, M-eslon, MSIR, Mitigo, Ms Contin, Statex
- Drug Type
- Small Molecule
- Chemical Formula
- C17H19NO3
- CAS Number
- 57-27-2
- Unique Ingredient Identifier
- 76I7G6D29C
- Background
Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805. It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. Morphine is still routinely used today, though there are a number of semi-synthetic opioids of varying strength such as codeine, fentanyl, methadone, hydrocodone, hydromorp...
- Indication
Morphine is used for the management of chronic, moderate to severe pain.
Opiods, including morphine, are effective for the short term management of pain. Patients taking opioids long term may need to be monitored for the development of physical dependence, addiction disorder, and drug abuse.
- Associated Conditions
- Chronic Pain, Severe Pain
- Associated Therapies
- -
Ultrasound Guidance for Interscalene Brachial Plexus Block
- Conditions
- Interventions
- First Posted Date
- 2008-06-20
- Last Posted Date
- 2009-11-16
- Lead Sponsor
- University of Parma
- Target Recruit Count
- 50
- Registration Number
- NCT00702416
- Locations
- 🇮🇹
University Hospital / Azienda Ospedaliero-Universitaria, Parma, PR, Italy
Controlled-Release Oxycodone For Postoperative Analgesia After Video-Assisted Thoracic Surgery
- Conditions
- Interventions
- First Posted Date
- 2008-05-21
- Last Posted Date
- 2012-01-06
- Lead Sponsor
- University of Parma
- Target Recruit Count
- 22
- Registration Number
- NCT00681174
- Locations
- 🇮🇹
University Hospital / Azienda Ospedaliero-Universitaria, Parma, PR, Italy
Mechanisms of Hypoglycemia Associated Autonomic Failure
- First Posted Date
- 2008-05-15
- Last Posted Date
- 2021-01-14
- Lead Sponsor
- Albert Einstein College of Medicine
- Target Recruit Count
- 116
- Registration Number
- NCT00678145
- Locations
- 🇺🇸
Albert Einstein College of Medicine / General Clinical Research Center, Bronx, New York, United States
Clonidine and Morphine in Caudal Anesthesia
- Conditions
- Interventions
- First Posted Date
- 2008-05-06
- Last Posted Date
- 2010-03-19
- Lead Sponsor
- Federal University of Minas Gerais
- Target Recruit Count
- 80
- Registration Number
- NCT00672347
- Locations
- 🇧🇷
Santa Casa de Belo Horizonte Hospital, Belo Horizonte, Minas Gerais, Brazil
Standard Pain Control or Intrathecal Therapy in Controlling Pain in Patients With Locally Advanced, Unresectable, or Metastatic Pancreatic Cancer
- Conditions
- Interventions
- First Posted Date
- 2008-04-17
- Last Posted Date
- 2014-10-08
- Target Recruit Count
- 1
- Registration Number
- NCT00660348
- Locations
- 🇺🇸
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, United States
A Randomized, Double-blind Comparison of Morphine and Sufentanil for Prehospital Traumatic Severe Acute Pain
- First Posted Date
- 2008-04-11
- Last Posted Date
- 2017-05-12
- Lead Sponsor
- University Hospital, Toulouse
- Target Recruit Count
- 108
- Registration Number
- NCT00656773
- Locations
- 🇫🇷
U H Toulouse Samu 31, Toulouse, France
Ibuprofen or Morphine in Treating Pain in Patients Undergoing Pleurodesis for Malignant Pleural Effusion
- Conditions
- First Posted Date
- 2008-03-26
- Last Posted Date
- 2009-07-08
- Lead Sponsor
- Oxford University Hospitals NHS Trust
- Target Recruit Count
- 320
- Registration Number
- NCT00644319
- Locations
- 🇬🇧
Oxford Radcliffe Hospital, Oxford, England, United Kingdom
Intra-Articular Morphine Versus Bupivacaine on Knee Motion in Patients With Osteoarthritis
- First Posted Date
- 2008-03-14
- Last Posted Date
- 2008-03-14
- Lead Sponsor
- Federal University of São Paulo
- Target Recruit Count
- 30
- Registration Number
- NCT00636415
- Locations
- 🇧🇷
Pain Setor of Federal University of Sao Paulo, Sao Paulo, SP, Brazil
Morphine Versus Methadone As First Line Strong Opioid for Cancer Pain
- First Posted Date
- 2008-03-12
- Last Posted Date
- 2016-05-09
- Lead Sponsor
- M.D. Anderson Cancer Center
- Target Recruit Count
- 36
- Registration Number
- NCT00634010
- Locations
- 🇺🇸
LBJ General Hospital, Houston, Texas, United States
🇺🇸The Michael E. DeBakey V.A. Medical Center, Houston, Texas, United States
🇺🇸University of Texas MD Anderson Cancer Center, Houston, Texas, United States
Ketamine Improves Post-Thoracotomy Analgesia
- Conditions
- Interventions
- First Posted Date
- 2008-02-29
- Last Posted Date
- 2008-02-29
- Lead Sponsor
- Tel-Aviv Sourasky Medical Center
- Target Recruit Count
- 44
- Registration Number
- NCT00625911
- Locations
- 🇮🇱
Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.