Morphine
- Generic Name
- Morphine
- Brand Names
- Arymo, Avinza, Doloral, Duramorph, Embeda, Infumorph, Kadian, M-ediat, M-eslon, MSIR, Mitigo, Ms Contin, Statex
- Drug Type
- Small Molecule
- Chemical Formula
- C17H19NO3
- CAS Number
- 57-27-2
- Unique Ingredient Identifier
- 76I7G6D29C
- Background
Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805. It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. Morphine is still routinely used today, though there are a number of semi-synthetic opioids of varying strength such as codeine, fentanyl, methadone, hydrocodone, hydromorp...
- Indication
Morphine is used for the management of chronic, moderate to severe pain.
Opiods, including morphine, are effective for the short term management of pain. Patients taking opioids long term may need to be monitored for the development of physical dependence, addiction disorder, and drug abuse.
- Associated Conditions
- Chronic Pain, Severe Pain
- Associated Therapies
- -
Platelet Reactivity with Fentanyl, Morphine, or No Narcotic
- Conditions
- Interventions
- First Posted Date
- 2022-05-10
- Last Posted Date
- 2024-11-28
- Lead Sponsor
- Spectrum Health - Lakeland
- Target Recruit Count
- 100
- Registration Number
- NCT05367336
- Locations
- 🇺🇸
Spectrum Health Lakeland, Saint Joseph, Michigan, United States
Pain Multidisciplinar Intervention in Major Trauma Patients
- Conditions
- Interventions
- First Posted Date
- 2022-05-02
- Last Posted Date
- 2024-08-20
- Lead Sponsor
- Nuria Llorach-Perucho
- Target Recruit Count
- 80
- Registration Number
- NCT05355441
- Locations
- 🇪🇸
Corporació Sanitària Parc Taulí, Sabadell, Barcelona, Spain
Intrathecal Morphine for Analgesia in Video-assisted Thoracic Surgery
- First Posted Date
- 2022-04-28
- Last Posted Date
- 2024-10-16
- Lead Sponsor
- University of Chicago
- Target Recruit Count
- 90
- Registration Number
- NCT05351229
- Locations
- 🇺🇸
University of Chicago, Chicago, Illinois, United States
Ultrasound-Guided TAP Block and Spinal Morphine for Pain Relief After Caesarean Section
- Conditions
- Interventions
- First Posted Date
- 2022-04-18
- Last Posted Date
- 2022-04-18
- Lead Sponsor
- Sohag University
- Target Recruit Count
- 60
- Registration Number
- NCT05331781
- Locations
- 🇪🇬
Faculty of Medicine, Sohag University, Sohag, Egypt
Methadone for 'Adenocarcinopathic' Pain Treatment
- First Posted Date
- 2022-04-13
- Last Posted Date
- 2022-12-05
- Lead Sponsor
- Ottawa Hospital Research Institute
- Registration Number
- NCT05325164
Ketorolac Applied by Continuous IV Infusion for Treatment of Moderately Severe Postoperative Pain Following Bunionectomy
- Conditions
- Interventions
- First Posted Date
- 2022-04-12
- Last Posted Date
- 2024-03-21
- Lead Sponsor
- NEMA Research, Inc.
- Target Recruit Count
- 360
- Registration Number
- NCT05324358
- Locations
- 🇺🇸
The Orthopedic Center, Tulsa, Oklahoma, United States
🇺🇸Sun City Clinical Research, Sun City, Arizona, United States
🇺🇸Trovare Clinical Research, Bakersfield, California, United States
Study of LYN-014 in Individuals With Opioid Use Disorder Who Are Stable on Methadone Therapy
- Conditions
- Interventions
- First Posted Date
- 2022-02-22
- Last Posted Date
- 2023-01-19
- Lead Sponsor
- Lyndra Inc.
- Registration Number
- NCT05251376
Subcutaneous Versus Intravenous Morphine When Switching From Oral to Parenteral Route in Palliative Cancer Patients
- First Posted Date
- 2022-02-11
- Last Posted Date
- 2023-12-26
- Lead Sponsor
- University Hospital, Akershus
- Target Recruit Count
- 60
- Registration Number
- NCT05236647
- Locations
- 🇳🇴
Akershus University Hospital, Lørenskog, Norway
Analgesic Effect of Intrathecal Morphine Combined With Low Dose Local Anesthetics on Postoperative Analgesia After Liver Resection
- Conditions
- Interventions
- First Posted Date
- 2022-01-26
- Last Posted Date
- 2022-01-26
- Lead Sponsor
- Yonsei University
- Target Recruit Count
- 90
- Registration Number
- NCT05208801
- Locations
- 🇰🇷
Yonsei University Health System, Severance Hospital, Seoul, Korea, Republic of
Postoperative Pain Control by Use of Many Drugs in Small Doses Intrathecally
- Conditions
- Interventions
- First Posted Date
- 2022-01-11
- Last Posted Date
- 2022-01-28
- Lead Sponsor
- Sohag University
- Target Recruit Count
- 60
- Registration Number
- NCT05186454
- Locations
- 🇪🇬
Fouad Soliman, Sohag, Egypt
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.