Desflurane, or I-653, a a volatile anesthetic that is more rapidly cleared and less metabolized than previous inhaled anesthetics such as methoxyflurane, sevoflurane, enflurane, or isoflurane.. It was developed in the late 1980s out of a need for a more rapidly acting and rapidly cleared inhaled anesthetic.
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Desflurane is indicated for the induction and maintenance of anesthesia in adults, as well as the maintenance of anesthesia in pediatric patients.
Sapporo Medical University, School of Medicine, Sappro, Hokkaido, Japan
Centre Léon Bérard, LYON Cedex 08, France
Severance Hospital, Seoul, Korea, Republic of
Nationwide Children's Hospital, Columbus, Ohio, United States
Seoul St. Mary's Hospital, Seoul, Korea, Republic of
University Hospital Zurich, Zurich, Switzerland
Hahnemann University Hospital, Philadelphia, Pennsylvania, United States
Stanford University School of Medicine, Stanford, California, United States
Songklanagarind Hospital, Hat yai, Songkhla, Thailand
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