Desflurane

Generic Name: Desflurane

Brand Names: Suprane

Drug Type: Small Molecule

Chemical Formula: C_₃H_₂F_₆O

CAS Number: 57041-67-5

Unique Ingredient Identifier: CRS35BZ94Q

Background: Desflurane, or I-653, a a volatile anesthetic that is more rapidly cleared and less metabolized than previous inhaled anesthetics such as methoxyflurane, sevoflurane, enflurane, or isoflurane.. It was developed in the late 1980s out of a need for a more rapidly acting and rapidly cleared inhaled anesthetic.
...

Indication: Desflurane is indicated for the induction and maintenance of anesthesia in adults, as well as the maintenance of anesthesia in pediatric patients.

Associated Conditions: -

Associated Therapies: Induction and Maintenance of General Anesthesia, Maintenance of anesthesia therapy

Clinical Trials

CTC Pancreatic Adenocarcinoma

Phase 4

Completed

Conditions: Adenocarcinoma
Circulating Tumor Cells
Pancreatic Neoplasms

Interventions: Drug: Desflurane

First Posted Date: 2015-01-09

Last Posted Date: 2019-12-13

Lead Sponsor: University of Zurich

Target Recruit Count: 86

Registration Number: NCT02335151

Locations: 🇨🇭
Kantonsspital St. Gallen, St. Gallen, Switzerland
🇨🇭
Kantonsspital Winterthur, Winterthur, Switzerland
🇨🇭
University Hospital Zurich, Zurich, Switzerland

and more 1 locations

Comparison of Emergence and Oxygenation During One-lung Ventilation With Desflurane and Propofol Anesthesia

Not Applicable

Active, not recruiting

Conditions: Lung Cancer

Interventions: Drug: propofol
Drug: desflurane

First Posted Date: 2014-12-24

Last Posted Date: 2024-04-05

Lead Sponsor: Juntendo University

Target Recruit Count: 80

Registration Number: NCT02324283

Locations: 🇯🇵
University of Juntendo, Bunkyo-ku, Tokyko, Japan

Emergence Times and Airway Reactions in General Laryngeal Mask Airway Anesthesia

Phase 3

Completed

Conditions: Anesthesia With Use of LMA (Laryngeal Mask Airway)

Interventions: Drug: Desflurane
Drug: propofol
Drug: Sevoflurane

First Posted Date: 2014-12-23

Last Posted Date: 2016-10-06

Lead Sponsor: RWTH Aachen University

Target Recruit Count: 352

Registration Number: NCT02322502

Locations: 🇩🇪
RWTH Aachen University; Department of Anesthesia, Aachen, Germany
🇩🇪
Kreiskliniken Reutlingen, Department of Anesthesia, Reutlingen, Germany
🇩🇪
University Hospital Ulm, Department of Anesthesia, Ulm, Germany

and more 1 locations

The Effect of Desflurane on Myocardial Function in Patients Undergoing Coronary Artery Bypass Grafting

Phase 4

Conditions: Coronary Artery Bypass Graft Redo
General Anesthetic Drug Adverse Reaction

Interventions: Drug: Desflurane
Drug: propofol
Drug: sufentanil

First Posted Date: 2014-08-11

Last Posted Date: 2014-08-11

Lead Sponsor: Huazhong University of Science and Technology

Target Recruit Count: 60

Registration Number: NCT02213718

Locations: 🇨🇳
Dept. of Anesthesiolgy, Tongji hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China

Anesthesia and Motor Evoked Potential (MEP) Recruitment

Not Applicable

Completed

Conditions: Idiopathic Scoliosis

Interventions: Drug: Desflurane

First Posted Date: 2014-07-24

Last Posted Date: 2020-09-22

Lead Sponsor: Children's Hospital Medical Center, Cincinnati

Target Recruit Count: 30

Registration Number: NCT02199314

Locations: 🇺🇸
Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States

Effect of Anesthetics on Oxygenation and Microcirculation During One-lung Ventilation

Not Applicable

Completed

Conditions: Mechanical Ventilation Complication

Interventions: Drug: propofol
Drug: desflurane

First Posted Date: 2014-07-16

Last Posted Date: 2016-10-13

Lead Sponsor: Seoul National University Hospital

Target Recruit Count: 104

Registration Number: NCT02191371

Locations: 🇰🇷
Seoul National University Hospital, Seoul, Korea, Republic of

Anesthetic Agents and Acute Kidney Injury After Liver Resection Surgery

Phase 4

Withdrawn

Conditions: Hepatocellular Carcinoma
Hepatoma
Cholangiocarcinoma
Gallbladder Neoplasms

Interventions: Drug: Desflurane
Drug: Sevoflurane

First Posted Date: 2014-06-25

Last Posted Date: 2023-05-03

Lead Sponsor: Tokyo Medical and Dental University

Registration Number: NCT02174575

Locations: 🇯🇵
Tokyo Medical and Dental University, Tokyo, Japan

The Effect of Propofol Based Total Intravenous Anesthesia on Oxidative Stress and Nitric Oxide

Phase 4

Completed

Conditions: Prostate Cancer

Interventions: Drug: Desflurane
Drug: propofol

First Posted Date: 2014-05-29

Last Posted Date: 2015-07-29

Lead Sponsor: Yonsei University

Target Recruit Count: 50

Registration Number: NCT02149628

Locations: 🇰🇷
Yonsei University, Gangnam Severance Hospital, Seoul, Korea, Republic of

Sevoflurane Versus Desflurane for Catheter-related Bladder Discomfort

Not Applicable

Completed

Conditions: Complications
Anesthesia
Urinary Bladder Neoplasms
Catheter Site Discomfort

Interventions: Drug: Sevoflurane
Drug: Desflurane

First Posted Date: 2014-03-26

Last Posted Date: 2014-10-02

Lead Sponsor: Seoul National University Hospital

Target Recruit Count: 108

Registration Number: NCT02096224

Locations: 🇰🇷
Seoul National University of Hospital, Seoul, Korea, Republic of

Effects of Desflurane Versus Propofol on Hemostasis During Splenectomy

Not Applicable

Completed

Conditions: Status; Splenectomy

Interventions: Drug: Desflurane
Drug: Propofol

First Posted Date: 2014-03-05

Last Posted Date: 2017-10-11

Lead Sponsor: Theodor Bilharz Research Institute

Target Recruit Count: 30

Registration Number: NCT02079064

Locations: 🇪🇬
Theodor Bilharz Research Institute, Giza, Egypt

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