Desflurane

Generic Name
Desflurane
Brand Names
Suprane
Drug Type
Small Molecule
Chemical Formula
C3H2F6O
CAS Number
57041-67-5
Unique Ingredient Identifier
CRS35BZ94Q
Background

Desflurane, or I-653, a a volatile anesthetic that is more rapidly cleared and less metabolized than previous inhaled anesthetics such as methoxyflurane, sevoflurane, enflurane, or isoflurane.. It was developed in the late 1980s out of a need for a more rapidly acting and rapidly cleared inhaled anesthetic.
...

Indication

Desflurane is indicated for the induction and maintenance of anesthesia in adults, as well as the maintenance of anesthesia in pediatric patients.

Associated Conditions
-
Associated Therapies
Induction and Maintenance of General Anesthesia, Maintenance of anesthesia therapy
Clinical Trials
Related News

The Effect of Preoperative Ketamine on the Emergence Characteristics in Children Undergoing Entropion Surgery

Not Applicable
Completed
Conditions
Entropion
Interventions
Drug: Sevoflurane
Drug: Desflurane
First Posted Date
2016-09-27
Last Posted Date
2019-05-03
Lead Sponsor
Inje University
Target Recruit Count
56
Registration Number
NCT02916407
Locations
🇰🇷

Haeundae paik hospital, inje university, Busan, Korea, Republic of

Power Spectral Analysis of EEG During Equi-MAC Inhalation Anesthesia

Phase 3
Completed
Conditions
Anesthesia
Interventions
Drug: Sevoflurane
Drug: Desflurane
First Posted Date
2016-08-19
Last Posted Date
2020-09-03
Lead Sponsor
Kangbuk Samsung Hospital
Target Recruit Count
90
Registration Number
NCT02872389
Locations
🇰🇷

Kangbuk Samsung Hospital, Seoul, Korea, Republic of

Comparison of Volatile Anesthetics on Cerebral Oxygenation During Controlled Hypotension

Phase 4
Completed
Conditions
Oxygen Saturation
Interventions
Drug: Sevoflurane
Drug: Desflurane
First Posted Date
2016-07-15
Last Posted Date
2020-08-19
Lead Sponsor
Ufuk University
Target Recruit Count
95
Registration Number
NCT02834845
Locations
🇹🇷

Ufuk University Hospital, Ankara, Turkey

Comparison of Analgesic Effect of Volatile Anesthetics

Phase 3
Completed
Conditions
Anesthesia
Interventions
Drug: Desflurane
Drug: Sevoflurane
First Posted Date
2016-07-12
Last Posted Date
2018-05-15
Lead Sponsor
Kangbuk Samsung Hospital
Target Recruit Count
90
Registration Number
NCT02830243
Locations
🇰🇷

Kangbuk Samsung Hospital, Seoul, Korea, Republic of

Decision Support for Intraoperative Low Blood Pressure

Not Applicable
Completed
Conditions
Hypotension
Interventions
Procedure: Attending real-time decision support
Procedure: In-room real-time decision support
Procedure: Attending feedback emails
Procedure: In-room provider feedback emails
Device: Anesthesia Information Management System (AIMS)
Device: Perioperative Data Warehouse (PDW)
Procedure: General anesthesia
Device: Pager system
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Procedure: Non-cardiac surgery
Drug: Propofol
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Drug: Desflurane
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Drug: Dobutamine
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First Posted Date
2016-04-04
Last Posted Date
2019-05-16
Lead Sponsor
Vanderbilt University Medical Center
Target Recruit Count
22435
Registration Number
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Locations
🇺🇸

Vanderbilt University Medical Center, Nashville, Tennessee, United States

Comparison of The Effects of Sevoflurane, Desflurane and Total Intravenous Anaesthesia on Pulmonary Function Tests

First Posted Date
2016-03-16
Last Posted Date
2016-03-16
Lead Sponsor
Istanbul University
Target Recruit Count
90
Registration Number
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Locations
🇹🇷

Istanbul University Cerrahpasa Medical Faculty Neurosurgery Department, Istanbul, Turkey

The Ratio of Hypnotic to Analgesic Potency of Volatile Anesthetics

Phase 3
Completed
Conditions
Anesthesia, General
Interventions
Drug: Sevoflurane
Drug: Desflurane
First Posted Date
2016-03-03
Last Posted Date
2018-05-08
Lead Sponsor
Kangbuk Samsung Hospital
Target Recruit Count
90
Registration Number
NCT02698514
Locations
🇰🇷

Kangbuk Samsung Hospital, Seoul, Korea, Republic of

Safety and Efficacy of Using SightSaver Visual Evoked Potential (VEP) for VEP Monitoring in Prone Spine Surgery

First Posted Date
2015-12-31
Last Posted Date
2017-08-01
Lead Sponsor
Ohio State University
Target Recruit Count
20
Registration Number
NCT02643615
Locations
🇺🇸

The Ohio State University Wexner Medical Center, Columbus, Ohio, United States

Recovery Profile Comparison Between Remifentanil-propofol or Desflurane Anesthesia Monitored With Bispectral Index.

First Posted Date
2015-12-16
Last Posted Date
2020-08-25
Lead Sponsor
Federal University of Minas Gerais
Target Recruit Count
40
Registration Number
NCT02631525

Real-time Decision Support for Postoperative Nausea and Vomiting (PONV) Prophylaxis

Not Applicable
Completed
Conditions
Postoperative Nausea and Vomiting
Interventions
Procedure: Automated recommendation at the start of the case
Procedure: Automated notification at the start of surgery
Procedure: Automated notification at the end of surgery
Device: Anesthesia Information Management System (AIMS)
Device: Perioperative Data Warehouse (PDW)
Procedure: General anesthesia
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Drug: Propofol
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First Posted Date
2015-12-09
Last Posted Date
2019-03-07
Lead Sponsor
Vanderbilt University
Target Recruit Count
27034
Registration Number
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Locations
🇺🇸

Vanderbilt University Medical Center, Nashville, Tennessee, United States

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