Clarithromycin
- Generic Name
- Clarithromycin
- Brand Names
- Biaxin, Biaxin Bid, Omeclamox, Prevpac, Voquezna 14 Day Triplepak 20;500;500
- Drug Type
- Small Molecule
- Chemical Formula
- C38H69NO13
- CAS Number
- 81103-11-9
- Unique Ingredient Identifier
- H1250JIK0A
- Background
Clarithromycin, a semisynthetic macrolide antibiotic derived from erythromycin, inhibits bacterial protein synthesis by binding to the bacterial 50S ribosomal subunit. Binding inhibits peptidyl transferase activity and interferes with amino acid translocation during the translation and protein assembly process. Clarithromycin may be bacteriostatic or bacteri...
- Indication
An alternative medication for the treatment of acute otitis media caused by H. influenzae, M. catarrhalis, or S. pneumoniae in patients with a history of type I penicillin hypersensitivity. Also for the treatment of pharyngitis and tonsillitis caused by susceptible Streptococcus pyogenes, as well as respiratory tract infections including acute maxillary sinu...
- Associated Conditions
- Acute Bacterial Exacerbation of Chronic Bronchitis (ABECB), Acute maxillary sinusitis, Bacterial Infections, Bartonellosis, Community Acquired Pneumonia (CAP), Duodenal ulcer caused by helicobacter pylori, Helicobacter Pylori Infection, Infective Endocarditis (IE), Lyme Disease, Mycobacterial Infections, Otitis Media (OM), Pertussis, Streptococcal Pharyngitis, Tonsillitis streptococcal, Uncomplicated skin and subcutaneous tissue bacterial infections
- Associated Therapies
- -
Recurrence Rate Comparison Between Esomeprazole and Lansoprazole in Eradicating Helicobacter Pylori Infection Among Children
- Conditions
- Interventions
- First Posted Date
- 2023-05-17
- Last Posted Date
- 2023-05-17
- Lead Sponsor
- Finni Kollins
- Target Recruit Count
- 51
- Registration Number
- NCT05861687
- Locations
- 🇮🇩
Universitas Sumatera Utara General Hospital, Medan, North Sumatera, Indonesia
🇮🇩Haji Adam Malik General Hospital, Medan, North Sumatera, Indonesia
The Potential of Givinostat as DDI Victim in Co-administration P-gp Inhibitor (Part 2)
- First Posted Date
- 2023-05-06
- Last Posted Date
- 2024-08-16
- Lead Sponsor
- Italfarmaco
- Target Recruit Count
- 20
- Registration Number
- NCT05845567
- Locations
- 🇵🇹
Hospital da Prelada, 3rd Floor & East Wing 4th Floor Rua Sarmento de Beires, Porto, Portugal
Effects of High-dose Dual Therapy and Bismuth Quadruple Therapy for Helicobacter Pylori Eradication on Intestinal Microecology
- Conditions
- Interventions
- First Posted Date
- 2023-02-24
- Last Posted Date
- 2023-11-14
- Lead Sponsor
- Xijing Hospital of Digestive Diseases
- Target Recruit Count
- 120
- Registration Number
- NCT05742568
- Locations
- 🇨🇳
Xijing Hosipital of Digestive Disease, Xi'an, Shaanxi, China
Efficacy of Therapy Based on Fecal Molecular Antimicrobial Susceptibility Tests for Helicobacter Pylori Infection
- Conditions
- Interventions
- First Posted Date
- 2023-02-08
- Last Posted Date
- 2023-05-15
- Target Recruit Count
- 855
- Registration Number
- NCT05718609
- Locations
- 🇨🇳
Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, Zhejiang, China
Electrophysiological Effects of Potential QT Prolonging Drugs
- First Posted Date
- 2023-02-08
- Last Posted Date
- 2023-06-22
- Lead Sponsor
- Food and Drug Administration (FDA)
- Target Recruit Count
- 44
- Registration Number
- NCT05716854
- Locations
- 🇺🇸
Spaulding Clinical Research, West Bend, Wisconsin, United States
A Drug Interaction Study of Clarithromycin and LY3502970 in Healthy Participants
- First Posted Date
- 2022-07-21
- Last Posted Date
- 2022-11-25
- Lead Sponsor
- Eli Lilly and Company
- Target Recruit Count
- 26
- Registration Number
- NCT05469126
- Locations
- 🇸🇬
Lilly Centre for Clinical Pharmacology, Singapore, Singapore
Efficacy and Safety of Dual Therapy as First-line Treatment for Hp Infection
- First Posted Date
- 2022-06-15
- Last Posted Date
- 2023-02-16
- Target Recruit Count
- 393
- Registration Number
- NCT05419674
- Locations
- 🇨🇳
Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, Zhejiang, China
High Dose Dual Therapy vs Clarithromycin Triple Therapy for Treatment Naive H Pylori Infection in an Urban Population
- Conditions
- Interventions
- First Posted Date
- 2022-04-22
- Last Posted Date
- 2023-02-01
- Lead Sponsor
- Icahn School of Medicine at Mount Sinai
- Target Recruit Count
- 112
- Registration Number
- NCT05342532
- Locations
- 🇺🇸
Mount Sinai Union Square Division of Digestive Diseases, New York, New York, United States
Susceptibility-Guided Therapy for Helicobacter Pylori Infection Treatment
- First Posted Date
- 2022-02-22
- Last Posted Date
- 2022-03-18
- Lead Sponsor
- Shanghai Zhongshan Hospital
- Target Recruit Count
- 388
- Registration Number
- NCT05250050
- Locations
- 🇨🇳
Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, Shanghai, China
🇨🇳Huashan Hospital, Fudan University, Shanghai, Shanghai, China
🇨🇳Zhongshan Hospital, Fudan University, Shanghai, Shanghai, China
Helicobacter Pylori Eradication With Probiotics Combined With Triple Therapy Versus Bismuth-containing Quadruple Therapy
- Conditions
- Interventions
- First Posted Date
- 2022-02-11
- Last Posted Date
- 2022-02-11
- Lead Sponsor
- Xijing Hospital of Digestive Diseases
- Target Recruit Count
- 600
- Registration Number
- NCT05237115
- Locations
- 🇨🇳
Xijing Hospital of Digestive Diseases, Xi'an, Shanxi, China
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.