Clarithromycin

Generic Name
Clarithromycin
Brand Names
Biaxin, Biaxin Bid, Omeclamox, Prevpac, Voquezna 14 Day Triplepak 20;500;500
Drug Type
Small Molecule
Chemical Formula
C38H69NO13
CAS Number
81103-11-9
Unique Ingredient Identifier
H1250JIK0A
Background

Clarithromycin, a semisynthetic macrolide antibiotic derived from erythromycin, inhibits bacterial protein synthesis by binding to the bacterial 50S ribosomal subunit. Binding inhibits peptidyl transferase activity and interferes with amino acid translocation during the translation and protein assembly process. Clarithromycin may be bacteriostatic or bacteri...

Indication

An alternative medication for the treatment of acute otitis media caused by H. influenzae, M. catarrhalis, or S. pneumoniae in patients with a history of type I penicillin hypersensitivity. Also for the treatment of pharyngitis and tonsillitis caused by susceptible Streptococcus pyogenes, as well as respiratory tract infections including acute maxillary sinu...

Associated Conditions
Acute Bacterial Exacerbation of Chronic Bronchitis (ABECB), Acute maxillary sinusitis, Bacterial Infections, Bartonellosis, Community Acquired Pneumonia (CAP), Duodenal ulcer caused by helicobacter pylori, Helicobacter Pylori Infection, Infective Endocarditis (IE), Lyme Disease, Mycobacterial Infections, Otitis Media (OM), Pertussis, Streptococcal Pharyngitis, Tonsillitis streptococcal, Uncomplicated skin and subcutaneous tissue bacterial infections
Associated Therapies
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Effect of Long Term Clarithromycin for Prevention of Exacerbations in Non-cystic Fibrosis Bronchiectasis in Asian Populations

First Posted Date
2020-12-08
Last Posted Date
2021-10-29
Lead Sponsor
Chinese University of Hong Kong
Target Recruit Count
40
Registration Number
NCT04658277
Locations
🇭🇰

Chinese University of Hong, Hong Kong, Please Select, Hong Kong

A Study of Bedaquiline Administered as Part of a Treatment Regimen With Clarithromycin and Ethambutol in Adult Patients With Treatment-refractory Mycobacterium Avium Complex-lung Disease (MAC-LD)

First Posted Date
2020-11-16
Last Posted Date
2024-12-10
Lead Sponsor
Janssen Pharmaceutical K.K.
Target Recruit Count
129
Registration Number
NCT04630145
Locations
🇰🇷

Chonnam National University Hospital, Gwangju, Korea, Republic of

🇯🇵

St. Luke's International Hospital, Chuo ku, Japan

🇯🇵

Fukui Prefectural Hospital, Fukui-shi, Japan

and more 52 locations

Quadruple vs Tailored Therapy in the Treatment of Helicobacter Pylori Infection

First Posted Date
2020-11-09
Last Posted Date
2020-11-09
Lead Sponsor
University of Split, School of Medicine
Target Recruit Count
80
Registration Number
NCT04621487
Locations
🇭🇷

University hospital Split, Split, Croatia

Interaction Study of Zanubrutinib With Moderate and Strong CYP3A Inhibitors in Participants With B-Cell Malignancies

First Posted Date
2020-09-16
Last Posted Date
2024-10-26
Lead Sponsor
BeiGene
Target Recruit Count
26
Registration Number
NCT04551963
Locations
🇦🇺

Concord Repatriation General Hospital, Concord, New South Wales, Australia

🇦🇺

John Flynn Private Hospital, Tugun, Queensland, Australia

🇦🇺

Royal Adelaide Hospital, Adelaide, South Australia, Australia

and more 4 locations

Study of Nitazoxanide (NTZ) for Helicobacter Pylori in Children

First Posted Date
2020-06-04
Last Posted Date
2020-06-04
Lead Sponsor
Tanta University
Target Recruit Count
100
Registration Number
NCT04415983
Locations
🇪🇬

Sherief Abd-Elsalam, Tanta, Egypt

Anti-inflammatory Clarithromycin for Improving COVID-19 Infection Early

First Posted Date
2020-05-21
Last Posted Date
2021-01-11
Lead Sponsor
Hellenic Institute for the Study of Sepsis
Target Recruit Count
90
Registration Number
NCT04398004
Locations
🇬🇷

2nd University Department of Internal Medicine, IPPOKRATEION General Hospital of Athens, Athens, Greece

🇬🇷

1st Department of Internal Medicine, General University Hospital of Ioannina, Ioánnina, Greece

🇬🇷

COVID-19 Department, General Hospital of Attica SISMANOGLEIO-AMALIA FLEMING, Marousi, Athens, Greece

and more 6 locations

Finding the Optimal Regimen for Mycobacterium Abscessus Treatment

First Posted Date
2020-03-17
Last Posted Date
2024-12-11
Lead Sponsor
The University of Queensland
Target Recruit Count
300
Registration Number
NCT04310930
Locations
🇦🇺

St George Hospital, Kogarah, New South Wales, Australia

🇦🇺

Austin Hospital, Heidelberg, Victoria, Australia

🇦🇺

Royal Melbourne Hospital, Parkville, Victoria, Australia

and more 47 locations
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