Mepivacaine
- Generic Name
- Mepivacaine
- Brand Names
- Carbocaine, Carbocaine With Neocobefrin, Isocaine, Isocaine With Levonordefrin, Polocaine, Scandonest, Scandonest L, Scandonest Plain
- Drug Type
- Small Molecule
- Chemical Formula
- C15H22N2O
- CAS Number
- 96-88-8
- Unique Ingredient Identifier
- B6E06QE59J
- Background
A local anesthetic that is chemically related to bupivacaine but pharmacologically related to lidocaine. It is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route. (From AMA Drug Evaluations, 1994, p168)
- Indication
For production of local or regional analgesia and anesthesia by local infiltration, peripheral nerve block techniques, and central neural techniques including epidural and caudal blocks.
- Associated Conditions
- Anaemia vitamin B6 deficiency, Anemia, Blood Loss Anemia, Diabetic Peripheral Neuropathy (DPN)
- Associated Therapies
- Local Anaesthesia therapy, Regional nerve block therapy, Lumbar epidural anesthesia therapy
2%-Mepivacaine With Two Different Vasoconstrictors Solutions in Third Molar Surgery a Comparative Study
- Conditions
- PainEdemaTrismus
- Interventions
- First Posted Date
- 2015-11-11
- Last Posted Date
- 2016-05-11
- Lead Sponsor
- University of Sao Paulo
- Target Recruit Count
- 30
- Registration Number
- NCT02603198
- Locations
- 🇧🇷
Maria Cristina Zindel Deboni, São Paulo, Brazil
Trial Evaluating Postop Pain and Muscle Strength Among Regional Anesthesia Techniques for Ambulatory ACL Reconstruction
- Conditions
- Rupture of Anterior Cruciate LigamentTear of Anterior Cruciate Ligament
- Interventions
- Procedure: adductor canal continuous nerve catheterProcedure: adductor canal nerve blockDrug: Normal Saline as bolus followed by bupivacaine
- First Posted Date
- 2015-10-22
- Last Posted Date
- 2019-12-11
- Lead Sponsor
- Vanderbilt University Medical Center
- Target Recruit Count
- 59
- Registration Number
- NCT02584452
- Locations
- 🇺🇸
Vanderbilt University Medical Center, Nashville, Tennessee, United States
The Impact of Chloroprocaine 3% for Ambulatory Foot Surgery on Perioperative Process Costs
- Conditions
- Impact of Anesthetic Choice on Costs
- Interventions
- First Posted Date
- 2015-04-02
- Last Posted Date
- 2020-03-11
- Lead Sponsor
- Ospedale Regionale Bellinzona e Valli
- Target Recruit Count
- 100
- Registration Number
- NCT02406703
Spinal Anesthesia Versus Combined Sciatic-femoral Nerve Block for Outpatient Knee Arthroscopy
- Conditions
- Knee Arthritis
- Interventions
- Procedure: Spinal anesthesiaProcedure: Sciatic-femoral Nerve BlockDevice: Sonoplex, Pajunk
- First Posted Date
- 2015-03-10
- Last Posted Date
- 2015-05-08
- Lead Sponsor
- ASST Gaetano Pini-CTO
- Target Recruit Count
- 100
- Registration Number
- NCT02384915
- Locations
- 🇮🇹
Istituto Ortopedico G. Pini, Milan, Milano, Italy
Stimulating Catheter for Lumbar Plexus Block: Better Postoperative Analgesia?
- Conditions
- Hip Replacement Arthroplasty
- Interventions
- Procedure: Spinal AnesthesiaProcedure: Local anesthetic infusionProcedure: Intravenous analgesiaProcedure: Opioids rescue analgesiaDevice: Stimulong, Pajunk, Germany.
- First Posted Date
- 2014-06-12
- Last Posted Date
- 2017-08-14
- Lead Sponsor
- ASST Gaetano Pini-CTO
- Target Recruit Count
- 64
- Registration Number
- NCT02162121
- Locations
- 🇮🇹
Istituto ortopedico Gaetano Pini, Milan, Italy
Mepivacaine-Tramadol on the Success of Inferior Alveolar Nerve Block in Symptomatic Irreversible Pulpitis
- Conditions
- Symptomatic Irreversible Pulpitis
- Interventions
- First Posted Date
- 2014-04-10
- Last Posted Date
- 2014-10-31
- Lead Sponsor
- Daniel Chavarría Bolaños
- Target Recruit Count
- 56
- Registration Number
- NCT02110966
- Locations
- 🇲🇽
Endodontics Master Degree program, Dentistry Faculty, San Luis Potosi University, San Luis Potosi, Mexico
Analgesia for Insertion of Intrauterine Contraception
- Conditions
- Insertion of Intrauterine Contraception
- Interventions
- Drug: Placebo
- First Posted Date
- 2014-03-05
- Last Posted Date
- 2018-04-26
- Lead Sponsor
- Karolinska Institutet
- Target Recruit Count
- 86
- Registration Number
- NCT02078063
- Locations
- 🇸🇪
Dept of Obstetrics and Gynecology, Danderyd Hospital, Stockholm, Sweden
🇸🇪Upplands Väsby Ungdomsmottagning, Stockholm, Sweden
Duration of Sciatic Nerve Block After Injection of Local Anesthetic In or Around the Nerve
- Conditions
- Orthopedic Surgical ProceduresPostoperative Pain
- Interventions
- Procedure: Perineural Injection for Subgluteal Sciatic Nerve BlockProcedure: Intraneural Injection for Subgluteal Sciatic Nerve BlockProcedure: Femoral Nerve BlockProcedure: Patient-controlled postoperative analgesia
- First Posted Date
- 2013-11-11
- Last Posted Date
- 2013-11-19
- Lead Sponsor
- University of Parma
- Target Recruit Count
- 120
- Registration Number
- NCT01981291
- Locations
- 🇮🇹
Anesthesia, Critical Care and Pain Medicine - University of Parma, Parma, PR, Italy
Treatment of Degenerative Disc Disease With Allogenic Mesenchymal Stem Cells (MSV)
- Conditions
- Low Back PainIntervertebral Disc DiseaseDegenerative Disc Disease
- Interventions
- Biological: Allogenic Mesenchymal Stromal Cells
- First Posted Date
- 2013-05-22
- Last Posted Date
- 2024-04-29
- Lead Sponsor
- Red de Terapia Celular
- Target Recruit Count
- 24
- Registration Number
- NCT01860417
- Locations
- 🇪🇸
Hospital Clinico Universitario, Valladolid, Spain
🇪🇸Instituto de Biologia y Genetica Molecular, Valladolid, Spain
Painless Local Infiltration Anesthesia
- Conditions
- Varicose VeinsPainSurgeryAnesthesia
- Interventions
- First Posted Date
- 2012-06-04
- Last Posted Date
- 2012-12-11
- Lead Sponsor
- Campus Bio-Medico University
- Target Recruit Count
- 100
- Registration Number
- NCT01611324
- Locations
- 🇮🇹
Policlinico Universitario Campus Bio-Medico, Rome, RM, Italy
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.