Clonidine
- Generic Name
- Clonidine
- Brand Names
- Catapres, Catapres-TTS, Catapres-tts-1, Duraclon, Kapvay, Nexiclon XR
- Drug Type
- Small Molecule
- Chemical Formula
- C9H9Cl2N3
- CAS Number
- 4205-90-7
- Unique Ingredient Identifier
- MN3L5RMN02
- Background
Clonidine is an imidazole derivate that acts as an agonist of alpha-2 adrenoceptors. This activity is useful for the treatment of hypertension, severe pain, and ADHD.
Clonidine was granted FDA approval on 3 September 1974.
- Indication
Clonidine tablets and transdermal systems are indicated for the treatment of hypertension alone or in combination with other medications. A clonidine injection is indicated for use with opiates in the treatment of severe cancer pain where opiates alone are insufficient. An extended release tablet of clonidine is indicated for the treatment of ADHD either alo...
- Associated Conditions
- Attention Deficit Hyperactivity Disorder (ADHD), Defiant Disorder, Oppositional, Gilles de la Tourette's Syndrome, Hot Flashes, Human Growth Hormone Deficiency, Hypertension, Opioid Withdrawal (Disorder), Pheochromocytoma, Postherpetic Neuralgia, Sialorrhea caused by clozapine, Diabetic diarrhea, Methadone withdrawal, Severe Cancer pain
- Associated Therapies
- Smoking, Cessation
Epidural Clonidine for Postoperative Hyperalgesia
- Conditions
- Locations
- 🇬🇧
Addenbrooke's Hospital, Cambridge, Cambridgeshire, United Kingdom
Preschool Supplement to Clonidine in ADHD (Kiddie-CAT)
- Conditions
- Interventions
- First Posted Date
- 2006-12-22
- Last Posted Date
- 2009-05-21
- Lead Sponsor
- University of Cincinnati
- Target Recruit Count
- 30
- Registration Number
- NCT00414921
- Locations
- 🇺🇸
Western Psychiatric Institute and Clinic, ADD Program, 3811 Ohara Street, Pittsburgh, Pennsylvania, United States
🇺🇸University of Rochester Medical Center, Department of Neurology, 919 Westfall Road, Building C, Rochester, New York, United States
🇺🇸University of Cincinnati, Department of Psychiatry, 231 Albert Sabin Way, M: 0559, Cincinnati, Ohio, United States
Comparison of Keppra and Clonidine in the Treatment of Tics
- Conditions
- Interventions
- First Posted Date
- 2006-09-01
- Last Posted Date
- 2011-09-07
- Lead Sponsor
- Harvey S. Singer
- Target Recruit Count
- 12
- Registration Number
- NCT00370838
- Locations
- 🇺🇸
Johns Hopkins Hospital, Baltimore, Maryland, United States
The Effects of Clonidine on the Diuretic Response in Cirrhotic Patients
- Conditions
- First Posted Date
- 2006-07-25
- Last Posted Date
- 2006-12-04
- Lead Sponsor
- CHU de Charleroi
- Target Recruit Count
- 64
- Registration Number
- NCT00356226
- Locations
- 🇧🇪
ISPPC CHU de Charleroi, Charleroi, Belgium
Clonidine Versus Adenosine to Treat Neuropathic Pain
- First Posted Date
- 2006-07-10
- Last Posted Date
- 2018-09-10
- Lead Sponsor
- Wake Forest University Health Sciences
- Target Recruit Count
- 24
- Registration Number
- NCT00349921
- Locations
- 🇺🇸
The Center for Clinical Research, 145 Kimel Park Drive, Winston-Salem, North Carolina, United States
🇺🇸Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, North Carolina, United States
Clonidine-induced Spinal Acetylcholine Release: Normal Volunteers vs. Neuropathic Pain
- First Posted Date
- 2006-07-10
- Last Posted Date
- 2018-09-10
- Lead Sponsor
- Wake Forest University Health Sciences
- Target Recruit Count
- 43
- Registration Number
- NCT00350532
- Locations
- 🇺🇸
The Center for Clinical Research, 145 Kimel Park Drive, Winston-Salem, North Carolina, United States
🇺🇸Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, North Carolina, United States
Effect of Clonidine on Responses to Imagery Scripts
- First Posted Date
- 2006-04-27
- Last Posted Date
- 2018-04-05
- Lead Sponsor
- National Institute on Drug Abuse (NIDA)
- Target Recruit Count
- 92
- Registration Number
- NCT00318760
- Locations
- 🇺🇸
National Institute on Drug Abuse, Baltimore, Maryland, United States
Effects of Topical Clonidine vs. Brimonidine on Choroidal Blood Flow and Intraocular Pressure During Isometric Exercise
- Conditions
- First Posted Date
- 2006-04-10
- Last Posted Date
- 2007-02-12
- Lead Sponsor
- Medical University of Vienna
- Target Recruit Count
- 18
- Registration Number
- NCT00312416
- Locations
- 🇦🇹
Department of Clinical Pharmacology, Vienna, Austria
Clonidine for Relapse Prevention in Buprenorphine-Maintenance Patients
- First Posted Date
- 2006-02-23
- Last Posted Date
- 2019-12-17
- Lead Sponsor
- National Institute on Drug Abuse (NIDA)
- Target Recruit Count
- 208
- Registration Number
- NCT00295308
- Locations
- 🇺🇸
National Institute on Drug Abuse, Baltimore, Maryland, United States
Treatment of Orthostatic Intolerance
- Conditions
- Interventions
- Drug: AtomoxetineDrug: AcetazolamideDietary Supplement: MelatoninOther: NO DrugDrug: Isosorbide DinitrateRadiation: PlaceboDevice: Breathing DeviceOther: Drinking WaterProcedure: IV SalineDevice: Abdominal binderDrug: IndomethacinDrug: MidodrineDrug: MecamylamineDrug: ClonidineDrug: EntacaponeDrug: memantineDrug: ModafinilDrug: OctreotideDrug: SertralineDrug: Atomoxetine & PropranololDrug: Entacapone & PropranololDrug: PropranololDrug: Modafinil & Propranolol
- First Posted Date
- 2005-12-06
- Last Posted Date
- 2024-10-02
- Lead Sponsor
- Satish R. Raj
- Target Recruit Count
- 150
- Registration Number
- NCT00262470
- Locations
- 🇺🇸
Vanderbilt University Autonomic Dysfunction Center, Nashville, Tennessee, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.