Clonidine
- Generic Name
- Clonidine
- Brand Names
- Catapres, Catapres-TTS, Catapres-tts-1, Duraclon, Kapvay, Nexiclon XR
- Drug Type
- Small Molecule
- Chemical Formula
- C9H9Cl2N3
- CAS Number
- 4205-90-7
- Unique Ingredient Identifier
- MN3L5RMN02
- Background
Clonidine is an imidazole derivate that acts as an agonist of alpha-2 adrenoceptors. This activity is useful for the treatment of hypertension, severe pain, and ADHD.
Clonidine was granted FDA approval on 3 September 1974.
- Indication
Clonidine tablets and transdermal systems are indicated for the treatment of hypertension alone or in combination with other medications. A clonidine injection is indicated for use with opiates in the treatment of severe cancer pain where opiates alone are insufficient. An extended release tablet of clonidine is indicated for the treatment of ADHD either alo...
- Associated Conditions
- Attention Deficit Hyperactivity Disorder (ADHD), Defiant Disorder, Oppositional, Gilles de la Tourette's Syndrome, Hot Flashes, Human Growth Hormone Deficiency, Hypertension, Opioid Withdrawal (Disorder), Pheochromocytoma, Postherpetic Neuralgia, Sialorrhea caused by clozapine, Diabetic diarrhea, Methadone withdrawal, Severe Cancer pain
- Associated Therapies
- Smoking, Cessation
Adjunctive Clonidine in the Sedation of Mechanically Ventilated Children
- Conditions
- Interventions
- First Posted Date
- 2009-08-14
- Last Posted Date
- 2014-08-13
- Lead Sponsor
- Hamilton Health Sciences Corporation
- Target Recruit Count
- 50
- Registration Number
- NCT00959062
- Locations
- 🇨🇦
London Health Sciences Centre, London, Ontario, Canada
🇨🇦McMaster Children's Hospital/Hamilton Health Sciences, Hamilton, Ontario, Canada
A Placebo-Controlled Study of Clonidine for Fecal Incontinence.
- First Posted Date
- 2009-04-21
- Last Posted Date
- 2014-03-06
- Lead Sponsor
- Mayo Clinic
- Target Recruit Count
- 44
- Registration Number
- NCT00884832
- Locations
- 🇺🇸
Mayo Clinic, Rochester, Minnesota, United States
Clonidine and Morphine in Caudal Anesthesia
- Conditions
- Interventions
- First Posted Date
- 2008-05-06
- Last Posted Date
- 2010-03-19
- Lead Sponsor
- Federal University of Minas Gerais
- Target Recruit Count
- 80
- Registration Number
- NCT00672347
- Locations
- 🇧🇷
Santa Casa de Belo Horizonte Hospital, Belo Horizonte, Minas Gerais, Brazil
Black Education and Treatment of Hypertension (BEAT HTN)
- First Posted Date
- 2008-04-21
- Last Posted Date
- 2012-12-04
- Lead Sponsor
- Creighton University
- Target Recruit Count
- 99
- Registration Number
- NCT00661895
- Locations
- 🇺🇸
Creighton Community Health Center, Omaha, Nebraska, United States
Clonidine Versus Midazolam for Premedication
- Conditions
- Interventions
- First Posted Date
- 2008-03-19
- Last Posted Date
- 2008-03-19
- Lead Sponsor
- University Hospital Schleswig-Holstein
- Target Recruit Count
- 60
- Registration Number
- NCT00638729
- Locations
- 🇩🇪
Department of Anaesthesiology and Intensive Care Medicine, University of Schleswig-Holstein Campus Kiel, Kiel, Germany
Epidural Clonidine for Lumbosacral Radiculopathy
- Conditions
- Interventions
- First Posted Date
- 2008-01-08
- Last Posted Date
- 2012-01-11
- Lead Sponsor
- Mayo Clinic
- Target Recruit Count
- 26
- Registration Number
- NCT00588354
- Locations
- 🇺🇸
Mayo Clinic, Rochester, Minnesota, United States
Clonidine to Prevent Implantable Cardiovertor Defibrillator Firing
- Conditions
- Interventions
- First Posted Date
- 2008-01-03
- Last Posted Date
- 2018-07-24
- Lead Sponsor
- James Martins
- Registration Number
- NCT00585871
- Locations
- 🇺🇸
UIHC, Iowa City, Iowa, United States
The Use of Clonidine in Pain and Anxiety Associated With Acute Burn Injury in Children
- First Posted Date
- 2007-12-24
- Last Posted Date
- 2015-02-23
- Target Recruit Count
- 9
- Registration Number
- NCT00580151
- Locations
- 🇺🇸
Shriners Hospital for Children; Shriners Burns Hospital, Galveston, Texas, United States
Nephropathy In Type 2 Diabetes and Cardio-renal Events
- First Posted Date
- 2007-09-27
- Last Posted Date
- 2020-08-03
- Lead Sponsor
- University of Campania "Luigi Vanvitelli"
- Target Recruit Count
- 850
- Registration Number
- NCT00535925
- Locations
- 🇮🇹
Department of Advanced Medical and Surgical Sciences, Università della Campania "Luigi Vanvitelli", Naples, Italy, Naples, Italy
Comparative Affect of a Continuous Epidural Infusion of Clonidine During Labour. Prospective Double Blind Randomized Trial
- Conditions
- First Posted Date
- 2007-02-21
- Last Posted Date
- 2009-06-30
- Lead Sponsor
- Hospices Civils de Lyon
- Target Recruit Count
- 85
- Registration Number
- NCT00437996
- Locations
- 🇫🇷
Henri Jacques CLEMENT, Lyon, France
🇫🇷Anesthesie Reanimation - Gynecologie - Hopital de La Croix Rousse, Lyon, France
Drug Development Updates
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