Acetylcholine

Generic Name
Acetylcholine
Brand Names
Miochol
Drug Type
Small Molecule
Chemical Formula
C7H16NO2
CAS Number
51-84-3
Unique Ingredient Identifier
N9YNS0M02X
Background

A neurotransmitter. Acetylcholine in vertebrates is the major transmitter at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system. It is generally not used as an administered drug because it is broken down very rapidly by cholinesterases, bu...

Indication

Used to obtain miosis of the iris in seconds after delivery of the lens in cataract surgery, in penetrating keratoplasty, iridectomy and other anterior segment surgery where rapid miosis may be required.

Associated Conditions
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Associated Therapies
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Early Neurovascular Adaptations in Aging Women

First Posted Date
2024-07-25
Last Posted Date
2024-10-01
Lead Sponsor
University of Missouri-Columbia
Target Recruit Count
64
Registration Number
NCT06520982
Locations
🇺🇸

University of Missouri-Columbia, Columbia, Missouri, United States

Comparing Approaches to Assess Nitric Oxide-dependent Cutaneous Vasodilation

Early Phase 1
Not yet recruiting
Conditions
Interventions
First Posted Date
2024-07-15
Last Posted Date
2024-07-15
Lead Sponsor
University of Iowa
Target Recruit Count
56
Registration Number
NCT06499844
Locations
🇺🇸

University of Iowa, Iowa City, Iowa, United States

Investigation of Endothelium-dependent Vasodilation in Human Gingiva

Not Applicable
Active, not recruiting
Conditions
Interventions
First Posted Date
2024-06-12
Last Posted Date
2024-06-12
Lead Sponsor
Semmelweis University
Target Recruit Count
80
Registration Number
NCT06454084
Locations
🇭🇺

Department for Restorative Dentistry and Endodontics, Semmelweis University, Budapest, Hungary

Estrogen and Microvascular Function

First Posted Date
2023-09-21
Last Posted Date
2023-09-21
Lead Sponsor
Medical College of Wisconsin
Target Recruit Count
20
Registration Number
NCT06043310
Locations
🇺🇸

Froedtert Hospital, Wauwatosa, Wisconsin, United States

Oxidative Stress in Microvascular Dysfunction Following Gestational Diabetes

First Posted Date
2023-07-14
Last Posted Date
2024-05-16
Lead Sponsor
Anna Stanhewicz, PhD
Target Recruit Count
28
Registration Number
NCT05946785
Locations
🇺🇸

University of Iowa, Iowa City, Iowa, United States

Role of NADPH Oxidase in Microvascular Dysfunction Following GDM

First Posted Date
2023-07-14
Last Posted Date
2024-12-03
Lead Sponsor
Anna Stanhewicz, PhD
Target Recruit Count
40
Registration Number
NCT05946798
Locations
🇺🇸

University of Iowa, Iowa City, Iowa, United States

Prenatal Aspirin and Postpartum Vascular Function

First Posted Date
2022-12-16
Last Posted Date
2024-05-28
Lead Sponsor
Anna Stanhewicz, PhD
Target Recruit Count
60
Registration Number
NCT05653973
Locations
🇺🇸

University of Iowa, Iowa City, Iowa, United States

Hot Flashes and Neurovascular Function in Women

First Posted Date
2022-01-18
Last Posted Date
2024-05-24
Lead Sponsor
Mayo Clinic
Target Recruit Count
120
Registration Number
NCT05193968
Locations
🇺🇸

Mayo Clinic in Rochester, Rochester, Minnesota, United States

Endothelium Dependent and Non-dependent Vasodilatation in Human Gingiva

First Posted Date
2021-06-09
Last Posted Date
2021-06-14
Lead Sponsor
Semmelweis University
Target Recruit Count
24
Registration Number
NCT04918563
Locations
🇭🇺

Semmelweis University, Department of Conservative Dentistry, Budapest, Hungary

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