Hydromorphone
- Generic Name
- Hydromorphone
- Brand Names
- Dilaudid, Exalgo, Hydromorph Contin, Hydromorphone Hp Forte
- Drug Type
- Small Molecule
- Chemical Formula
- C17H19NO3
- CAS Number
- 466-99-9
- Unique Ingredient Identifier
- Q812464R06
- Background
Hydromorphone is a pure opioid, a semi-synthetic hydrogenated ketone derivative of morphine that has been available clinically since 1920. Structurally, hydromorphone derived from morphine in the modification of the hydroxyl group in the carbon 6 to a carbonyl and the absence of a double bond between the carbon 7 and 8. Due to these modifications, it present...
- Indication
Hydromorphone is indicated for the management of moderate to severe acute pain and severe chronic pain. Due to its addictive potential and overdose risk, hydromorphone is only prescribed when other first-line treatments have failed.
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- Associated Conditions
- Neuropathic Pain, Refractory Chronic Cough, Moderate to severe pain
- Associated Therapies
- -
PCA vs Non-PCA Intravenous Hydromorphone Titration for Severe Cancer Pain
- First Posted Date
- 2017-12-18
- Last Posted Date
- 2021-03-08
- Lead Sponsor
- Fujian Cancer Hospital
- Target Recruit Count
- 214
- Registration Number
- NCT03375515
- Locations
- 🇨🇳
Rongbo Lin, Fuzhou, Fujian, China
Effect of Tramadol in Prevention of Postpartum Depression
- Conditions
- Interventions
- First Posted Date
- 2017-10-13
- Last Posted Date
- 2019-08-14
- Lead Sponsor
- Xinqiao Hospital of Chongqing
- Target Recruit Count
- 1230
- Registration Number
- NCT03309163
- Locations
- 🇨🇳
Xinqiao Hospital, Third Military Medical University, Chongqing, Chongqing, China
Intravenous Lidocaine Randomized Comparative Effectiveness Trial
- First Posted Date
- 2017-10-03
- Last Posted Date
- 2020-08-10
- Lead Sponsor
- Montefiore Medical Center
- Target Recruit Count
- 154
- Registration Number
- NCT03300674
- Locations
- 🇺🇸
Montefiore Medical Center, Bronx, New York, United States
Epidural and Intravenous Patient-Controlled Analgesia Following Lumbar Spinal Fusion Surgery
- First Posted Date
- 2017-04-14
- Last Posted Date
- 2023-10-26
- Lead Sponsor
- University of Texas Southwestern Medical Center
- Target Recruit Count
- 46
- Registration Number
- NCT03115151
- Locations
- 🇺🇸
University Of Texas Southwestern Medical Center, Zale University Hospital, Dallas, Texas, United States
🇺🇸University of Texas Southwestern Medical Center, Dallas, Texas, United States
Acetaminophen IV vs Hydromorphone IV in the ED
- First Posted Date
- 2017-04-11
- Last Posted Date
- 2017-11-17
- Lead Sponsor
- Montefiore Medical Center
- Target Recruit Count
- 220
- Registration Number
- NCT03107481
- Locations
- 🇺🇸
Montefiore Medical Center, Bronx, New York, United States
The Effectiveness of IV/PO Acetaminophen in the Perioperative Period in Reducing Opiate Use After Lumbar Spine Fusion
- Conditions
- Interventions
- First Posted Date
- 2017-04-07
- Last Posted Date
- 2019-10-08
- Lead Sponsor
- University of Southern California
- Target Recruit Count
- 28
- Registration Number
- NCT03104816
- Locations
- 🇺🇸
Keck Hospital of USC, Los Angeles, California, United States
Dextromethorphan Use in Multimodal Analgesia Regimens for Total Knee Arthroplasty
- First Posted Date
- 2016-12-09
- Last Posted Date
- 2019-05-14
- Lead Sponsor
- University of Southern California
- Target Recruit Count
- 23
- Registration Number
- NCT02987920
Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery
- Conditions
- Interventions
- First Posted Date
- 2016-11-08
- Last Posted Date
- 2017-03-20
- Target Recruit Count
- 80
- Registration Number
- NCT02958566
- Locations
- 🇺🇸
Uicomp, Peoria, Illinois, United States
Does IVPCA Increase Opioid Consumption and Side Effects in Fast Track Orthopedic Procedures?
- Conditions
- Interventions
- First Posted Date
- 2016-08-26
- Last Posted Date
- 2016-08-26
- Lead Sponsor
- Mount Sinai Hospital, Canada
- Target Recruit Count
- 80
- Registration Number
- NCT02880800
- Locations
- 🇨🇦
Mount Sinai Hospital, Toronto, Ontario, Canada
Pain Medications in Children Undergoing Strabismus Surgery
- First Posted Date
- 2016-06-03
- Last Posted Date
- 2016-06-03
- Lead Sponsor
- St. Louis Children's Hospital
- Target Recruit Count
- 128
- Registration Number
- NCT02789969
- Locations
- 🇺🇸
St. Louis Children's Hospital, St. Louis, Missouri, United States
Drug Development Updates
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