Amoxicillin
- Generic Name
- Amoxicillin
- Brand Names
- Amoxil, Augmentin, Clavulin, Moxatag, Omeclamox, Prevpac, Talicia, Voquezna 14 Day Dualpak 20;500, Voquezna 14 Day Triplepak 20;500;500
- Drug Type
- Small Molecule
- Chemical Formula
- C16H19N3O5S
- CAS Number
- 26787-78-0
- Unique Ingredient Identifier
- 9EM05410Q9
- Background
Amoxicillin, or BRL-2333, is a penicillin G derivative first described in the literature in 1972. Amoxicillin has similar activity to penicillin and ampicillin, but leads to higher serum concentrations than ampicillin.
Amoxicillin was granted FDA approval on 18 January 1974.
- Indication
Amoxicillin alone is indicated to treat susceptible bacterial infections of the ear, nose, throat, genitourinary tract, skin, skin structure, and lower respiratory tract. Amoxicillin is given with calvulanic acid to treat acute bacterial sinusitis, community acquired pneumonia, lower respiratory tract infections, acute bacterial otitis media, skin and skin s...
- Associated Conditions
- Acute Bacterial Sinusitis (ABS), Acute Otitis Media (AOM), Bacterial Infections, Community Acquired Pneumonia (CAP), Duodenal ulcer caused by helicobacter pylori, Genitourinary tract infection, Helicobacter Pylori Infection, Lower Respiratory Tract Infection (LRTI), Peptic Ulcer With H. Pylori Infection, Sinusitis, Skin and Subcutaneous Tissue Bacterial Infections, Urinary Tract Infection, Acute, uncomplicated Gonorrhea, Ear, nose, and throat infections
- Associated Therapies
- -
Intraluminal Amoxicillin Powder Monotherapy for Helicobacter Pylori Infection
- Conditions
- Interventions
- First Posted Date
- 2018-05-11
- Last Posted Date
- 2019-02-15
- Lead Sponsor
- Mackay Memorial Hospital
- Target Recruit Count
- 20
- Registration Number
- NCT03521726
- Locations
- 🇨🇳
Division of Gastroenterology and Department of Internal Medicine, Mackay Memorial Hospital, Taipei, Taiwan, Taipei, Taiwan
Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants
- Conditions
- Interventions
- Drug: Tranexamic acid (TXA)Drug: HydrocodoneDrug: labetalolDrug: metforminDrug: nifedipineDrug: oxycodoneDrug: clindamycinDrug: azithromycinDrug: escitalopramDrug: sertralineDrug: CiprofloxacinDrug: ondansetronDrug: DoxycyclineDrug: LevofloxacinDrug: MethylphenidateDrug: CitalopramDrug: SumatriptanDrug: CyclobenzaprineDrug: FurosemideDrug: RosuvastatinDrug: GabapentinDrug: HydrochlorothiazideDrug: HydroxyureaDrug: TrazodoneDrug: TopiramateDrug: ValganciclovirDrug: RemdesivirDrug: VenlafaxineDrug: VerapamilDrug: FluvoxamineDrug: AnakinraDrug: TocilizumabDrug: AmoxicillinDrug: BupropionDrug: BuprenorphineDrug: LevetiracetamDrug: ParoxetineDrug: Duloxetine
- First Posted Date
- 2018-04-27
- Last Posted Date
- 2024-12-17
- Lead Sponsor
- Duke University
- Target Recruit Count
- 1600
- Registration Number
- NCT03511118
- Locations
- 🇺🇸
Northwestern University, Chicago, Illinois, United States
🇺🇸Ann and Robert H. Lurie Childrens Hospital of Chicago, Chicago, Illinois, United States
🇺🇸Loma Linda University Health, Loma Linda, California, United States
Penicillin Allergy in Shfayim Clinic
- First Posted Date
- 2018-04-17
- Last Posted Date
- 2018-04-17
- Lead Sponsor
- Clalit Health Services
- Target Recruit Count
- 100
- Registration Number
- NCT03499457
Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of After Administrations of DWP14012 Alone and Combinations of DWP14012, Clarithromycin and Amoxicillin in Healthy Male Subjects
- Conditions
- Interventions
- First Posted Date
- 2018-04-04
- Last Posted Date
- 2019-06-26
- Lead Sponsor
- Daewoong Pharmaceutical Co. LTD.
- Target Recruit Count
- 48
- Registration Number
- NCT03487562
- Locations
- 🇰🇷
Seoul National University Hospital, Seoul, Korea, Republic of
The Norwegian Antibiotics for Pneumonia in Children Study
- Conditions
- Interventions
- First Posted Date
- 2018-02-26
- Last Posted Date
- 2018-04-11
- Lead Sponsor
- Oslo University Hospital
- Target Recruit Count
- 884
- Registration Number
- NCT03446534
- Locations
- 🇳🇴
Ålesund Hospital Trust, Ålesund, Norway
🇳🇴Nordlandssykehuset Bodø, Bodø, Norway
🇳🇴Stavanger University Hospital, Stavanger, Norway
Safety Trial of Herbal Melanin in Gastritis Patients
- Conditions
- Interventions
- First Posted Date
- 2018-02-09
- Last Posted Date
- 2018-02-09
- Target Recruit Count
- 132
- Registration Number
- NCT03428568
Tailored Therapy for Helicobacter Pylori Rescue Treatment
- Conditions
- Interventions
- First Posted Date
- 2018-01-29
- Last Posted Date
- 2018-08-07
- Lead Sponsor
- Shanghai Jiao Tong University School of Medicine
- Target Recruit Count
- 200
- Registration Number
- NCT03413020
- Locations
- 🇨🇳
Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, Shanghai, China
The Effect of Antibiotic Prophylaxis Associated With Dental Implant Surgery
- Conditions
- Interventions
- First Posted Date
- 2018-01-26
- Last Posted Date
- 2021-08-25
- Lead Sponsor
- Malmö University
- Target Recruit Count
- 474
- Registration Number
- NCT03412305
- Locations
- 🇸🇪
Malmö university, Malmö, Sweden
High Dose of Dual Therapy Plus Bismuth for Helicobacter Pylori Treatment
- Conditions
- Interventions
- First Posted Date
- 2018-01-23
- Last Posted Date
- 2018-11-05
- Lead Sponsor
- Shanghai Jiao Tong University School of Medicine
- Target Recruit Count
- 160
- Registration Number
- NCT03405584
- Locations
- 🇨🇳
Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, Shanghai, China
Oral Challenge in the Pediatric ED
- Conditions
- Interventions
- First Posted Date
- 2018-01-19
- Last Posted Date
- 2024-05-16
- Lead Sponsor
- Medical College of Wisconsin
- Target Recruit Count
- 116
- Registration Number
- NCT03404804
- Locations
- 🇺🇸
David Vyles, Milwaukee, Wisconsin, United States
Drug Development Updates
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