Amoxicillin

Generic Name
Amoxicillin
Brand Names
Amoxil, Augmentin, Clavulin, Moxatag, Omeclamox, Prevpac, Talicia, Voquezna 14 Day Dualpak 20;500, Voquezna 14 Day Triplepak 20;500;500
Drug Type
Small Molecule
Chemical Formula
C16H19N3O5S
CAS Number
26787-78-0
Unique Ingredient Identifier
9EM05410Q9
Background

Amoxicillin, or BRL-2333, is a penicillin G derivative first described in the literature in 1972. Amoxicillin has similar activity to penicillin and ampicillin, but leads to higher serum concentrations than ampicillin.

Amoxicillin was granted FDA approval on 18 January 1974.

Indication

Amoxicillin alone is indicated to treat susceptible bacterial infections of the ear, nose, throat, genitourinary tract, skin, skin structure, and lower respiratory tract. Amoxicillin is given with calvulanic acid to treat acute bacterial sinusitis, community acquired pneumonia, lower respiratory tract infections, acute bacterial otitis media, skin and skin s...

Associated Conditions
Acute Bacterial Sinusitis (ABS), Acute Otitis Media (AOM), Bacterial Infections, Community Acquired Pneumonia (CAP), Duodenal ulcer caused by helicobacter pylori, Genitourinary tract infection, Helicobacter Pylori Infection, Lower Respiratory Tract Infection (LRTI), Peptic Ulcer With H. Pylori Infection, Sinusitis, Skin and Subcutaneous Tissue Bacterial Infections, Urinary Tract Infection, Acute, uncomplicated Gonorrhea, Ear, nose, and throat infections
Associated Therapies
-

Systemic Probiotics in the Periodontal Treatment

First Posted Date
2018-11-07
Last Posted Date
2020-01-13
Lead Sponsor
Belén Retamal-Valdes
Target Recruit Count
176
Registration Number
NCT03733379
Locations
🇧🇷

Federal University of Paraná, Curitiba, Paraná, Brazil

🇧🇷

University of Guarulhos, Guarulhos, São Paulo, Brazil

Analysis of the Impact of Helicobacter Pylori on Salivary Microbiome in Adults

First Posted Date
2018-11-05
Last Posted Date
2018-11-05
Lead Sponsor
Shanghai Jiao Tong University School of Medicine
Target Recruit Count
60
Registration Number
NCT03730766
Locations
🇨🇳

Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, Shanghai, China

Evaluation of Saccharomyces Boulardii Combined With Standard Quadruple Therapy for Eradication of Helicobacter Pylori

First Posted Date
2018-09-28
Last Posted Date
2021-10-26
Lead Sponsor
Huazhong University of Science and Technology
Target Recruit Count
360
Registration Number
NCT03688828
Locations
🇨🇳

Tongji Hospital, Tongji Medical School, Huazhong University of Science and Technology, Wuhan, Hubei, China

Treatment of High-Risk Moderate Acute Malnutrition Using Expanded Admission Criteria

First Posted Date
2018-08-27
Last Posted Date
2020-09-01
Lead Sponsor
Washington University School of Medicine
Target Recruit Count
1322
Registration Number
NCT03647150
Locations
🇸🇱

Project Peanut Butter, Freetown, Sierra Leone

Penicillin Allergy De-Labelling in Elective Surgical Patients (PADLES)

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2018-07-31
Last Posted Date
2018-07-31
Lead Sponsor
The Leeds Teaching Hospitals NHS Trust
Target Recruit Count
150
Registration Number
NCT03607734
Locations
🇬🇧

Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom

Antibiotics Prior to Mini-screw Implant Insertion

First Posted Date
2018-07-11
Last Posted Date
2020-11-12
Lead Sponsor
St. Louis University
Target Recruit Count
31
Registration Number
NCT03582605
Locations
🇺🇸

Saint Louis University Center for Advanced Dental Education, Saint Louis, Missouri, United States

Azithromycin for Uncomplicated Severe Acute Malnutrition in Burkina Faso (Pilot)

First Posted Date
2018-06-26
Last Posted Date
2022-09-01
Lead Sponsor
University of California, San Francisco
Target Recruit Count
301
Registration Number
NCT03568643
Locations
🇧🇫

Centre de Recherche en santé de nouna, Nouna, Boucle Du Mouhoun, Burkina Faso

Genotypic Resistance Guided Therapy for Refractory H. Pylori Infection

First Posted Date
2018-06-13
Last Posted Date
2018-06-13
Lead Sponsor
National Taiwan University Hospital
Target Recruit Count
320
Registration Number
NCT03555526
Locations
🇨🇳

Jyh-Ming Liou, Taipei, Taiwan, Taiwan-, Taiwan

Accuracy and Consequences of Using Trial-of-antibiotics for TB Diagnosis (ACT-TB Study)

First Posted Date
2018-06-04
Last Posted Date
2021-04-28
Lead Sponsor
London School of Hygiene and Tropical Medicine
Target Recruit Count
1583
Registration Number
NCT03545373
Locations
🇲🇼

University of Malawi College of Medicine, Blantyre, Southern, Malawi

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