Oxycodone

Generic Name
Oxycodone
Brand Names
Endocet, Endodan Reformulated May 2009, Nalocet, Oxaydo, Oxy.IR, Oxycontin, Oxyneo, Percocet, Prolate, Rivacocet, Roxicet, Roxicodone, Roxybond, Targin, Targiniq, Xolox, Xtampza
Drug Type
Small Molecule
Chemical Formula
C18H21NO4
CAS Number
76-42-6
Unique Ingredient Identifier
CD35PMG570
Background

Oxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917. It is currently indicated as an immediate release product for moderate to severe pain and as an extended release product for chronic moderate to severe pain requiring continuous opioid analgesics for an extended period. The first oxycodone containing product, Percodan, wa...

Indication

Oxycodone is indicated for the treatment of moderate to severe pain. There is also an extended release formulation indicated for chronic moderate to severe pain requiring continuous opioid analgesics for an extended period.

Associated Conditions
Severe Acute Pain, Severe Pain, Severe, Chronic Pain, Acute, moderate Pain, Chronic, moderate Pain
Associated Therapies
-

Abuse Potential Study of PF-00345439

Phase 1
Completed
Conditions
Interventions
First Posted Date
2013-11-18
Last Posted Date
2016-04-04
Lead Sponsor
Pain Therapeutics
Target Recruit Count
67
Registration Number
NCT01986283
Locations
🇺🇸

Lifetree Clinical Research, Salt Lake City, Utah, United States

Evaluate The Pharmacokinetics and Safety Of Oxycodone Oral Solution In Pediatric and Adolescent Subjects

Phase 4
Completed
Conditions
Interventions
First Posted Date
2013-10-09
Last Posted Date
2023-01-11
Lead Sponsor
VistaPharm, Inc.
Target Recruit Count
97
Registration Number
NCT01959204
Locations
🇺🇸

Miami Children's Hospital, Miami, Florida, United States

🇺🇸

Tampa General Hospital, Tampa, Florida, United States

🇺🇸

Cincinnati Children's Hospital, Cincinnati, Ohio, United States

and more 6 locations

Prospective Longitudinal Observational Study to Evaluate the Clinical Characteristics and Opioids Treatments in Patients With Breakthrough Cancer Pain

First Posted Date
2013-09-19
Last Posted Date
2016-04-14
Lead Sponsor
Mario Negri Institute for Pharmacological Research
Target Recruit Count
150
Registration Number
NCT01946555
Locations
🇮🇹

A.O. Universitaria Parma, Parma, Italia, Italy

🇮🇹

Ospedale di Piacenza, Piacenza, Italy

🇮🇹

Ospedale Magati, Scandiano, Italia, Italy

and more 8 locations

Food Effect And Relative Bioavailability Study Of Oxycodone in Healthy Volunteers

Phase 1
Completed
Conditions
Interventions
First Posted Date
2013-08-16
Last Posted Date
2015-08-31
Lead Sponsor
Pain Therapeutics
Target Recruit Count
18
Registration Number
NCT01924676
Locations
🇺🇸

Pfizer Investigational Site, Baltimore, Maryland, United States

Determine the Safety and Efficacy of Oxy/Nal Tablets Compared to Oxy PR in Subjects With Cancer Pain

Phase 3
Completed
Conditions
Interventions
First Posted Date
2013-06-24
Last Posted Date
2019-10-04
Lead Sponsor
Mundipharma (China) Pharmaceutical Co. Ltd
Target Recruit Count
232
Registration Number
NCT01885182
Locations
🇨🇳

The sixth hospital of shanghai, Shanghai, China

🇨🇳

Tianjin Cancer Hospital, Tianjin, China

🇨🇳

Beijing Friendship Hospital, Beijing, China

and more 25 locations

Evaluation of the Tolerability of Switching Subjects on Chronic ATC Opioid Therapy to Buprenorphine HCl Buccal Film

First Posted Date
2013-06-06
Last Posted Date
2017-02-27
Lead Sponsor
BioDelivery Sciences International
Target Recruit Count
39
Registration Number
NCT01871285
Locations
🇺🇸

CRI Lifetree (Lifetree Clinical Research), Salt Lake, Utah, United States

🇺🇸

CRI Lifetree, Philadelphia, Pennsylvania, United States

🇺🇸

Vince and Associates Clinical Research, Inc., Overland Park, Kansas, United States

Emergency Department (ED) Drug Interaction in Emergency Department Patients

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2013-05-22
Last Posted Date
2016-05-05
Lead Sponsor
University of Colorado, Denver
Target Recruit Count
502
Registration Number
NCT01859715
Locations
🇺🇸

University of Colorado, Aurora, Colorado, United States

A Study to Characterize the Abuse Liability of Intravenous Oxycodone Alone or in Combination With Intravenous Naltrexone in Healthy, Non-Dependent, Recreational Opioid Users

First Posted Date
2013-04-05
Last Posted Date
2013-10-08
Lead Sponsor
Pfizer
Target Recruit Count
89
Registration Number
NCT01825447
Locations
🇺🇸

Pfizer Investigational Site, Salt Lake City, Utah, United States

RCT Comparing the Analgesic Efficacy of 4 Therapeutic Strategies Based on 4 Different Major Opioids (Fentanyl, Oxycodone, Buprenorphine vs Morphine) in Cancer Patients With Moderate/Severe Pain, at the Moment of Starting 3rd Step of WHO Analgesic Ladder.

First Posted Date
2013-03-12
Last Posted Date
2015-12-24
Lead Sponsor
Mario Negri Institute for Pharmacological Research
Target Recruit Count
518
Registration Number
NCT01809106
Locations
🇮🇹

Multimedica, Sesto San Giovanni, Italy

🇮🇹

Istituto Scientifico San Raffaele, Milano, Italy

🇮🇹

Arcispedale S. Maria Nuova Azienda Ospedaliera, Reggio Emilia, RE, Italy

and more 6 locations

Pharmacokinetics And Relative Bioavailability Study Of Oxycodone in Healthy Volunteers

Phase 1
Completed
Conditions
Interventions
First Posted Date
2012-10-30
Last Posted Date
2015-08-31
Lead Sponsor
Pain Therapeutics
Target Recruit Count
19
Registration Number
NCT01717027
Locations
🇺🇸

Pfizer Investigational Site, New Haven, Connecticut, United States

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