Acetaminophen
- Generic Name
- Acetaminophen
- Brand Names
- Acephen, Acetadryl, Allzital, Apadaz, Arthriten Inflammatory Pain, Bupap, Butapap, Cetafen, Children's Silapap, Coricidin Hbp Cold & Flu, Darvocet-N, Dayquil Sinex, Diphen, Dolofin, Dologen, Dologesic Reformulated Jun 2016, Duralgina, Dvorah, Endocet, Esgic, Exaprin, Excedrin, Excedrin PM Triple Action, Excedrin Tension Headache, Feverall, Fioricet, Fioricet With Codeine, Goody's Back & Body Pain Relief, Goody's Body Pain, Goody's Extra Strength, Goody's Headache Relief Shot, Goody's PM, Hycet, Legatrin PM, Little Fevers, Lorcet, Lortab, Mapap, Mersyndol, Midol Complete, Midol Cramps & Bodyaches, Nalocet, Norco, Orbivan, Pamprin Max Formula, Pamprin Multi-symptom, Panadol, Pediacare Children's Fever Reducer Pain Reliever, Percocet, Percogesic Reformulated Jan 2011, Pharbetol, Premsyn Pms, Prolate, Rivacocet, Robaxacet, Robaxacet-8, Roxicet, Sudafed PE Sinus Headache, Tactinal, Tencon, Trezix, Triatec, Triatec-30, Triatec-8, Tylenol, Tylenol PM, Tylenol With Codeine, Ultracet, Vanatol, Vanatol S, Vanquish, Xodol, Xolox, Zamicet, Zflex, Zydone
- Drug Type
- Small Molecule
- Chemical Formula
- C8H9NO2
- CAS Number
- 103-90-2
- Unique Ingredient Identifier
- 362O9ITL9D
- Background
Acetaminophen (paracetamol), also commonly known as Tylenol, is the most commonly taken analgesic worldwide and is recommended as first-line therapy in pain conditions by the World Health Organization (WHO). It is also used for its antipyretic effects, helping to reduce fever. This drug was initially approved by the U.S. FDA in 1951 and is available in a var...
- Indication
In general, acetaminophen is used for the treatment of mild to moderate pain and reduction of fever. It is available over the counter in various forms, the most common being oral forms.
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- Associated Conditions
- Acute Gouty Arthritis, Acute Musculoskeletal Pain, Allergic Reaction, Allergy to Tree Pollen, Ankylosing Spondylitis (AS), Chills, Cold, Common Cold, Cough, Cough caused by Common Cold, Coughing caused by Flu caused by Influenza, Dyskinesia of the Biliary Tract, Dyskinesia of the Urinary Tract, Febrile Convulsions, Febrile Illness Acute, Fever, Fibromyalgia, Flu caused by Influenza, Headache, Joint dislocations, Menstrual Distress (Dysmenorrhea), Mild pain, Muscle Inflammation, Muscle Injuries, Muscle Spasms, Musculoskeletal Pain, Myalgia, Nasal Congestion, Neuropathic Pain, Osteoarthritis (OA), Pain, Postoperative pain, Premenstrual cramps, Rheumatoid Arthritis, Rhinopharyngitis, Rhinorrhoea, Severe Pain, Sinusitis, Spasms, Spastic Pain of the Gastrointestinal Tract, Sprains, Symptoms Cold, Tension Headache, Toothache, Upper Respiratory Tract Infection, Whiplash Syndrome, Acute Torticollis, Articular inflammation, Cold or flu syndrome, Mild to moderate pain, Minor aches and pains, Minor pain, Moderate Pain, Moderate to severe pain
- Associated Therapies
- Airway secretion clearance therapy, Anti-spasmodics, Bronchodilation
Intratumor Injection of Anti-Mesothelin Immunotoxin LMB-100 With Ipilimumab in Malignant Mesothelioma
- First Posted Date
- 2021-04-12
- Last Posted Date
- 2024-02-02
- Lead Sponsor
- National Cancer Institute (NCI)
- Target Recruit Count
- 2
- Registration Number
- NCT04840615
- Locations
- 🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States
Sphenopalatine Ganglion Block for Management of Post- Dural Puncture Headache in Obstetric Patients
- Conditions
- Interventions
- First Posted Date
- 2021-03-11
- Last Posted Date
- 2022-02-16
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 40
- Registration Number
- NCT04793490
- Locations
- 🇪🇬
Ain Shams University Hospital, Cairo, Abassia, Egypt
Non-Opioid Pain Medications After Intracapsular Adenotonsillectomy
- First Posted Date
- 2021-03-10
- Last Posted Date
- 2024-08-16
- Lead Sponsor
- David Chi, MD
- Target Recruit Count
- 73
- Registration Number
- NCT04791761
- Locations
- 🇺🇸
UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, United States
Preemptive Analgesia With Celecoxib for Acute Dental Pain Management
- Conditions
- Interventions
- First Posted Date
- 2021-03-10
- Last Posted Date
- 2024-03-27
- Target Recruit Count
- 65
- Registration Number
- NCT04790812
- Locations
- 🇺🇸
The University of Texas Health Science Center at Houston, Houston, Texas, United States
Usefulness of Acetaminophen Associated With Strong Opioids for Acute Pain in Cancer Patients
- First Posted Date
- 2021-03-03
- Last Posted Date
- 2021-08-13
- Lead Sponsor
- Pontificia Universidad Catolica de Chile
- Target Recruit Count
- 112
- Registration Number
- NCT04779567
- Locations
- 🇨🇱
Universidad Catolica de Chile, Santiago, Chile
Pre Emptive Analgesics for Pain Relief in Impacted Lower Third Molar Surgery
- First Posted Date
- 2021-02-24
- Last Posted Date
- 2021-02-24
- Lead Sponsor
- Melaka Manipal Medical College
- Target Recruit Count
- 60
- Registration Number
- NCT04769557
- Locations
- 🇲🇾
Melaka manipal medical college, Melaka, Malaysia
ESP in Breast Surgery Due to Cancer
- First Posted Date
- 2021-01-27
- Last Posted Date
- 2021-11-09
- Lead Sponsor
- Medical University of Lublin
- Target Recruit Count
- 75
- Registration Number
- NCT04726878
- Locations
- 🇵🇱
II Department of Anesthesia and Intensive Care, Medical University of Lublin, Lublin, Poland
OTC Naproxen and Acetaminophen Anti-Inflammatory Action in Dental Implant Patients
- Conditions
- Interventions
- First Posted Date
- 2021-01-05
- Last Posted Date
- 2024-05-16
- Lead Sponsor
- Hersh, Elliot V., DMD, MS, PhD
- Target Recruit Count
- 30
- Registration Number
- NCT04694300
- Locations
- 🇺🇸
University of Pennsylvania School of Dental Medicine, Philadelphia, Pennsylvania, United States
Detection of Paracetamol Concentration in Blood-, Saline- and Urine Samples - a Validation Study for a Novel Technique
- Conditions
- Interventions
- First Posted Date
- 2020-12-31
- Last Posted Date
- 2021-12-08
- Lead Sponsor
- Johanna Kujala
- Target Recruit Count
- 12
- Registration Number
- NCT04690673
- Locations
- 🇫🇮
Helsinki university hospital, Helsinki, Finland
Non-inferiority Study of Ocrelizumab and Rituximab in Active Multiple Sclerosis
- Conditions
- Interventions
- First Posted Date
- 2020-12-30
- Last Posted Date
- 2024-05-16
- Lead Sponsor
- Rigshospitalet, Denmark
- Target Recruit Count
- 600
- Registration Number
- NCT04688788
- Locations
- 🇩🇰
Department of Neurology, Herlev Hospital, Herlev, Denmark
🇩🇰Department of Neurology, Aalborg University Hospital, Aalborg, Denmark
🇩🇰Department of Neurology, Aarhus University Hospital, Aarhus, Denmark
Drug Development Updates
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