Metoclopramide
- Generic Name
- Metoclopramide
- Brand Names
- Gimoti, Reglan
- Drug Type
- Small Molecule
- Chemical Formula
- C14H22ClN3O2
- CAS Number
- 364-62-5
- Unique Ingredient Identifier
- L4YEB44I46
- Background
Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of life and poses a significant burden on the healthcare system. Metoclopramide is a dopamine antagonist used to treat nausea and vomiting that may be associated with diabetic gastroparesis in addition to gastroesophageal reflux disease (GER...
- Indication
Metoclopramide in the oral tablet form is used for symptomatic treatment of both acute and recurrent diabetic gastroparesis, in addition to the treatment of gastroesophageal reflux disease (GERD) in patients who have failed to respond to traditional therapy. A nasal spray formulation is also indicated to treat adults with acute, recurrent diabetic gastropare...
- Associated Conditions
- Chemotherapy-Induced Nausea and Vomiting, Diabetic Gastroparesis, Dyspepsia, Flatulence, Gastroesophageal Reflux, Gastroparesis, Hiccups, Hyperacidity, Migraine, Nausea and vomiting, Post Operative Nausea and Vomiting (PONV), Radiation-Induced Nausea and Vomiting, Acute, recurrent Diabetic Gastroparesis, Gastric bezoar
- Associated Therapies
- Facilitation of small bowel intubation therapy, Gastric emptying for radiologic procedures
Optimization of the Bowel Preparation Regimen for the PillCam® COLON 2 Capsule Endoscopy Procedure
- First Posted Date
- 2015-06-25
- Last Posted Date
- 2017-03-07
- Lead Sponsor
- Medtronic - MITG
- Target Recruit Count
- 122
- Registration Number
- NCT02481219
- Locations
- 🇺🇸
Franklin Gastroenterology, PLLC, Franklin, Tennessee, United States
🇺🇸Indiana University Hospital, Indianapolis, Indiana, United States
🇺🇸Pinnacle Research Group, LLC, Anniston, Alabama, United States
PEP uP Protocol in Surgical Patients
- First Posted Date
- 2015-06-02
- Last Posted Date
- 2020-10-27
- Target Recruit Count
- 36
- Registration Number
- NCT02459275
- Locations
- 🇺🇸
Brigham and Women's Hospital, Boston, Massachusetts, United States
🇺🇸Jamaica Hospital Medical Center, Jamaica, New York, United States
🇺🇸Virginia Tech Carilion School of Medicine, Roanoke, Virginia, United States
Nefopam vs Tramadol in the Prevention of Post Anaesthetic Shivering
- First Posted Date
- 2015-05-12
- Last Posted Date
- 2018-07-17
- Lead Sponsor
- Lagos State Health Service Commission
- Target Recruit Count
- 130
- Registration Number
- NCT02441673
Anesthetics in Rhytidoplasty - A Comparison Study
- First Posted Date
- 2015-04-07
- Last Posted Date
- 2015-04-07
- Lead Sponsor
- Mercy Facial Plastic Surgery Center
- Target Recruit Count
- 30
- Registration Number
- NCT02410460
- Locations
- 🇺🇸
Mercy Facial Plastic Surgery Center, Springfield, Missouri, United States
A Cost Effective Treatment for Headache in Pregnancy When Acetaminophen Alone is Ineffective.
- Conditions
- Interventions
- First Posted Date
- 2014-11-20
- Last Posted Date
- 2018-04-02
- Lead Sponsor
- St. Louis University
- Target Recruit Count
- 70
- Registration Number
- NCT02295280
- Locations
- 🇺🇸
Saint Louis University, Saint Louis, Missouri, United States
Dopamine D-2 Antagonist Use in Poor Responders in IVF: a Randomized Controlled Trial
- Conditions
- Interventions
- First Posted Date
- 2014-10-13
- Last Posted Date
- 2022-04-11
- Lead Sponsor
- Mount Sinai Hospital, Canada
- Registration Number
- NCT02262923
- Locations
- 🇨🇦
Mount Sinai Hospital, Toronto, Ontario, Canada
Comparison of Efficacy Dimenhydrinate and Metoclopramide in the Treatment of Nausea Due to Vertigo
- Conditions
- Interventions
- First Posted Date
- 2014-10-01
- Last Posted Date
- 2014-10-01
- Lead Sponsor
- Pamukkale University
- Target Recruit Count
- 200
- Registration Number
- NCT02253524
Metoclopramide as Treatment of Clozapine-induced Hypersalivation
- Conditions
- Interventions
- First Posted Date
- 2014-08-21
- Last Posted Date
- 2014-08-21
- Lead Sponsor
- Beersheva Mental Health Center
- Target Recruit Count
- 61
- Registration Number
- NCT02222220
- Locations
- 🇮🇱
Be'er Sheva Mental Health Center,, Be'er Sheva, Israel
Comparison of Gabapentin and Metoclopramide for Treating Hyperemesis Gravidarum
- First Posted Date
- 2014-06-13
- Last Posted Date
- 2023-02-14
- Lead Sponsor
- State University of New York at Buffalo
- Target Recruit Count
- 31
- Registration Number
- NCT02163434
- Locations
- 🇺🇸
University of Rochester, Rochester, New York, United States
🇺🇸University at Buffalo, Buffalo, New York, United States
MEtoclopramide, DExamethasone or Axoli to Prevent or Delay Chemotherapy-induced Nausea and Vomiting in Moderately Emetogenic Non-AC-based Chemotherapy
- Conditions
- Interventions
- First Posted Date
- 2014-05-12
- Last Posted Date
- 2020-03-31
- Lead Sponsor
- Amsterdam UMC, location VUmc
- Target Recruit Count
- 249
- Registration Number
- NCT02135510
- Locations
- 🇳🇱
Tergooiziekenhuizen, Hilversum, Noord Holland, Netherlands
🇳🇱Rijnstate, Arnhem, Netherlands
🇳🇱Medisch Centrum Alkmaar, Alkmaar, Noord-Holland, Netherlands
Drug Development Updates
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