Metronidazole

Generic Name
Metronidazole
Brand Names
Flagyl, Flagystatin, Likmez, Metrocream, Metrogel, Metrolotion, Nidagel, Noritate, Nuvessa, Pylera, Rosadan, Vandazole
Drug Type
Small Molecule
Chemical Formula
C6H9N3O3
CAS Number
443-48-1
Unique Ingredient Identifier
140QMO216E
Background

Metronidazole is a commonly used antibiotic, belonging to the nitroimidazole class of antibiotics. It is frequently used to treat gastrointestinal infections as well as trichomoniasis and giardiasis, and amebiasis which are parasitic infections. Metronidazole has been used as an antibiotic for several decades, with added antiparasitic properties that set it ...

Indication

Metronidazole is indicated for the treatment of confirmed trichomoniasis caused by Trichomonas vaginalis (except for in the first trimester of pregnancy) and the patient's sexual partners, bacterial vaginosis, certain types of amebiasis, and various anaerobic infections. The above anaerobic infections may occur on the skin and skin structures, the abdomen, t...

Associated Conditions
Abscess Brain, Abscess, Intra-Abdominal, Anaerobic Bacterial Infection, Bacterial Endocarditis, Bacterial Peritonitis, Bacterial Septicemia, Bacterial Vaginosis (BV), Balantidiasis, Bone and Joint Infections, Central Nervous System Bacterial Infections, Empyema, Endometritis, Endomyometritis, Facial Rosacea, Giardiasis, Gynecological Infection, Helicobacter Pylori Infection, Inflammatory Papule, Inflammatory pustules, Liver Abscess, Amebic, Lower respiratory tract infection bacterial, Lung Abscess, Meningitis, Mixed Vaginal Infections, Mixed Vaginal Infections caused by Trichomonas Vaginalis, candida albicans, Periodontitis, Pneumonia, Postoperative Infections, Pouchitis, Skin and skin structure infections, Tetanus, Trichomonas Vaginitis, Tubo-ovarian abscess, Vaginal Candidiasis, Vaginitis Trichomonal, Vulvovaginitis, Acute Intestinal amebiasis, Asymptomatic Trichomoniasis, Entamoeba histolytica, Hepatic abscess, Intra-abdominal bacterial infections, Post-surgical vaginal cuff infection, Refractory Sinusitis, Symptomatic Trichomoniasis
Associated Therapies
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Kefazolin Versus Kefazolin Plus Metronidazole to Reduce Postpartum Infection

First Posted Date
2021-03-11
Last Posted Date
2021-03-11
Lead Sponsor
University of Pretoria
Target Recruit Count
1000
Registration Number
NCT04792710
Locations
🇿🇦

Kalafong Provincial Tertiary Hospital, Pretoria, Gauteng Province, South Africa

Bismuth-Metronidazole Triple Therapy for H. Pylori First-line Treatment

First Posted Date
2020-12-14
Last Posted Date
2020-12-22
Lead Sponsor
Shanghai Zhongshan Hospital
Target Recruit Count
270
Registration Number
NCT04667299
Locations
🇨🇳

Zhongshan Hospital, Fudan University, Shanghai, Shanghai, China

Quadruple vs Tailored Therapy in the Treatment of Helicobacter Pylori Infection

First Posted Date
2020-11-09
Last Posted Date
2020-11-09
Lead Sponsor
University of Split, School of Medicine
Target Recruit Count
80
Registration Number
NCT04621487
Locations
🇭🇷

University hospital Split, Split, Croatia

A Randomized Controlled Trial of Treatment of Bacterial Vaginosis

Phase 4
Terminated
Conditions
Interventions
First Posted Date
2020-10-08
Last Posted Date
2023-06-15
Lead Sponsor
Ohio State University
Target Recruit Count
16
Registration Number
NCT04578015
Locations
🇺🇸

The Ohio State University Wexner Medical Center OB/GYN Maternal and Fetal Medicine, Columbus, Ohio, United States

Intravenous Triple Therapy in the Treatment of Helicobacter Pylori Infection and Related Complications Caused by Active Peptic Ulcer Disease

First Posted Date
2020-06-16
Last Posted Date
2020-08-27
Lead Sponsor
Shanghai Jiao Tong University School of Medicine
Target Recruit Count
60
Registration Number
NCT04432233
Locations
🇨🇳

Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, Shanghai, China

Study of Nitazoxanide (NTZ) for Helicobacter Pylori in Children

First Posted Date
2020-06-04
Last Posted Date
2020-06-04
Lead Sponsor
Tanta University
Target Recruit Count
100
Registration Number
NCT04415983
Locations
🇪🇬

Sherief Abd-Elsalam, Tanta, Egypt

Alternative Antibiotic Regimen in Periodontitis Treatment

First Posted Date
2020-04-20
Last Posted Date
2020-04-20
Lead Sponsor
Istanbul Medipol University Hospital
Target Recruit Count
74
Registration Number
NCT04353362
Locations
🇹🇷

Begum Alkan, Istanbul, Turkey

Personalized AZithromycin/metronidAZole Therapy in Pediatric Crohn's Disease (CD)

First Posted Date
2019-12-04
Last Posted Date
2024-08-05
Lead Sponsor
University of North Carolina, Chapel Hill
Target Recruit Count
12
Registration Number
NCT04186247
Locations
🇺🇸

UCSF Benioff Children's Hospital, San Francisco, California, United States

🇺🇸

University of Pittsburgh Medical Center, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, United States

🇨🇦

IWK Health Centre, Halifax, Canada

and more 2 locations
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