Quinine

Generic Name
Quinine
Brand Names
Qualaquin
Drug Type
Small Molecule
Chemical Formula
C20H24N2O2
CAS Number
130-95-0
Unique Ingredient Identifier
A7V27PHC7A
Background

An alkaloid derived from the bark of the cinchona tree. It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633. Quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose. It was used commonly and as a bitter and f...

Indication

For the treatment of malaria and leg cramps

Associated Conditions
Uncomplicated Malaria caused by Plasmodium falciparum
Associated Therapies
-

A Trial of the Efficacy of Artesunate and Three Quinine Regimens in the Treatment of Severe Malaria in Children at the Ebolowa Regional Hospital - Cameroon

Phase 3
Completed
Conditions
Interventions
First Posted Date
2015-09-30
Last Posted Date
2015-10-01
Lead Sponsor
University of Yaounde 1
Target Recruit Count
238
Registration Number
NCT02563704

Evaluation of a Compliance Marker in Prescription Opioid Abusers With Chronic Pain

First Posted Date
2014-10-28
Last Posted Date
2017-02-10
Lead Sponsor
Georgetown University
Registration Number
NCT02276989
Locations
🇺🇸

Georgetown University, Washington, District of Columbia, United States

Parenteral Artesunate Compared to Quinine as a Cause of Late Anaemia in African Children With Malaria

Phase 4
Completed
Conditions
Interventions
First Posted Date
2014-03-20
Last Posted Date
2015-06-01
Lead Sponsor
University of Oxford
Target Recruit Count
217
Registration Number
NCT02092766
Locations
🇨🇩

Kinshasa School of Public Health, Kinshasa, Congo, The Democratic Republic of the

Interactions Between Intravenous Cocaine and Acetazolamide or Quinine

Phase 1
Completed
Conditions
First Posted Date
2013-05-10
Last Posted Date
2018-07-05
Lead Sponsor
National Institute on Drug Abuse (NIDA)
Target Recruit Count
14
Registration Number
NCT01851473
Locations
🇺🇸

National Institute on Drug Abuse, Baltimore, Maryland, United States

Intravenous Artesunate and Malaria

Phase 4
Conditions
Interventions
First Posted Date
2013-03-06
Last Posted Date
2013-03-06
Lead Sponsor
University of Khartoum
Target Recruit Count
80
Registration Number
NCT01805232
Locations
🇸🇩

Kassala, Kassala, Sudan

Superiority of ArTiMist Versus Quinine in Children With Severe Malaria

First Posted Date
2010-12-10
Last Posted Date
2014-02-28
Lead Sponsor
Proto Pharma Ltd
Target Recruit Count
151
Registration Number
NCT01258049
Locations
🇷🇼

Rwinkwavu District Hospital, Rwinkwavu, Eastern Province, Rwanda

🇬🇭

Navrongo Health Research Centre, Navrongo, Ghana

🇧🇫

Centre National de Recherche et de Formation sur le Paludisme (CNRFP), Ouagadougou, Burkina Faso

Efficacy of ArTiMist™ in Children

Phase 2
Completed
Conditions
Interventions
First Posted Date
2010-01-12
Last Posted Date
2011-01-27
Lead Sponsor
Proto Pharma Ltd
Target Recruit Count
31
Registration Number
NCT01047436

Quinine vs. Artemether/Lumefantrine in Uncomplicated Malaria During Pregnancy

Phase 4
Completed
Conditions
Interventions
First Posted Date
2007-07-03
Last Posted Date
2022-06-03
Lead Sponsor
Epicentre
Target Recruit Count
300
Registration Number
NCT00495508
Locations
🇺🇬

Epicentre, Mbarara, Mbarara District, Uganda

Ototoxicity of Artemether / Lumefantrine (Coartem) and Other Antimalarials

Phase 4
Completed
Conditions
First Posted Date
2007-03-23
Last Posted Date
2007-03-23
Lead Sponsor
Jimma University
Registration Number
NCT00451139
Locations
🇪🇹

Jimma University Hospital, Jimma, Ethiopia

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