Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID). NSAIDs inhibit cyclooxygenase (COX)-1 and-2 which are the enzyme responsible for producing prostaglandins (PGs). PGs contribute to inflammation and pain signalling. Diclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and in...
Diclofenac is indicated for use in the treatment of pain and inflammation from varying sources including inflammatory conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis, as well as injury-related inflammation due to surgery and physical trauma. It is often used in combination with misoprostol as a gastro-protective agent in p...
Dept. of Dermatology, Freiburg, Germany
Klinik fuer Dermatologie, Venerologie und Allergologie der Charite, Berlin, Germany
Praxis Priv.-Doz. Dr. med. Dirschka, Wuppertal, Germany
Pfizer Investigational Site, Wigan, United Kingdom
Pfizer Investigational Site, Siena, Italy
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.