MedPath

Clomifene

Generic Name
Clomifene
Brand Names
Clomid
Drug Type
Small Molecule
Chemical Formula
C26H28ClNO
CAS Number
911-45-5
Unique Ingredient Identifier
1HRS458QU2
Background

A triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue.

Indication

Used mainly in female infertility due to anovulation (e.g. due to polycystic ovary syndrome) to induce ovulation.

Associated Conditions
Ovulatory Dysfunction

Vitamin D Supplementation and Improvement of PCOS Therapy and IVF Outcomes in Infertile Saudi Women

Not Applicable
Conditions
Pathologic Processes
Vitamin D Supplement
Polycystic Ovary Syndrome
IVF
Female Infertility
Vitamin D Deficiency
Interventions
First Posted Date
2021-11-04
Last Posted Date
2021-11-04
Lead Sponsor
Umm Al-Qura University
Target Recruit Count
700
Registration Number
NCT05106712

Pharmacokinetic Evaluation of Serum Testosterone Concentrations After Administration of Clomiphene Citrate

Phase 2
Withdrawn
Conditions
Testosterone Deficiency
Interventions
First Posted Date
2021-10-27
Last Posted Date
2024-11-04
Lead Sponsor
Weill Medical College of Cornell University
Target Recruit Count
40
Registration Number
NCT05096169
Locations
🇺🇸

Weill Cornell Medicine, New York, New York, United States

Growth Hormone Pretreatment in Poseidon Type IV Undergoing ICSI Using Minimal Induction Protocol: A Randomized Controlled Trial

Not Applicable
Conditions
Poor Response to Ovulation Induction Poseidon Type IV
Interventions
First Posted Date
2021-10-22
Last Posted Date
2021-10-22
Lead Sponsor
Ain Shams Maternity Hospital
Target Recruit Count
132
Registration Number
NCT05089344
Locations
🇪🇬

AinShams University, Cairo, Egypt

Sex Hormone Supplementation and Rotator Cuff Repair: A Preliminary Randomized Trial

Phase 2
Recruiting
Conditions
Rotator Cuff Tears
Interventions
Procedure: Rotator Cuff Repair
First Posted Date
2021-06-30
Last Posted Date
2024-12-06
Lead Sponsor
University of Utah
Target Recruit Count
58
Registration Number
NCT04944836
Locations
🇺🇸

University of Utah, Salt Lake City, Utah, United States

Effect of Vitamin D Oral Supplementation in Poly Csytic Ovarian Women Resistant to Clomiphene Citrate

Phase 1
Conditions
Vitamin D Deficiency
Polycystic Ovary Syndrome
Clomiphene Allergy
Interventions
First Posted Date
2021-06-08
Last Posted Date
2021-06-08
Lead Sponsor
rana alaaeldin aly ibrahim nasr
Target Recruit Count
100
Registration Number
NCT04916925

Parameters Declaring PCO Infertile Patients Either Sensitive or Resistant to Different Doses of Clomiphene Citrate.

Conditions
PCO
Clomiphene Citrate
Induction of Ovulation
Interventions
First Posted Date
2021-05-14
Last Posted Date
2022-02-16
Lead Sponsor
Ain Shams Maternity Hospital
Target Recruit Count
100
Registration Number
NCT04887402
Locations
🇪🇬

Ain Shams University, Cairo, Egypt

BMI Effect on the Response to Ovulation Induction in Letrozole vs Clomid

Phase 4
Conditions
Subfertility
Interventions
First Posted Date
2020-04-02
Last Posted Date
2020-04-02
Lead Sponsor
Cairo University
Target Recruit Count
160
Registration Number
NCT04331197

Myo-inositol Versus Clomiphene Citrate in PCOS

Phase 4
Terminated
Conditions
Ovulation Induction
Polycystic Ovary Syndrome
Clomiphene
Inositol
Interventions
First Posted Date
2020-03-13
Last Posted Date
2022-12-21
Lead Sponsor
University Hospital, Ghent
Target Recruit Count
12
Registration Number
NCT04306692
Locations
🇧🇪

University Hospital, Ghent, Belgium

Coenzyme q 10 and Fertility Outcome in Women With Clomiphene Resistant PCOS

Phase 4
Completed
Conditions
Coenzyme q10
Interventions
First Posted Date
2020-03-10
Last Posted Date
2020-11-25
Lead Sponsor
Karachi Medical and Dental College
Target Recruit Count
149
Registration Number
NCT04302532
Locations
🇵🇰

Aziz medical center, Karachi, Sindh, Pakistan

Incremental Clomiphene Citrate Doses in Successive Cycles and FSH, LH and Steroid Hormone Levels

Phase 4
Completed
Conditions
Unexplained Infertility
Ovulation Disorder
Interventions
First Posted Date
2019-12-26
Last Posted Date
2021-02-03
Lead Sponsor
Bagcilar Training and Research Hospital
Target Recruit Count
50
Registration Number
NCT04210765
Locations
🇹🇷

Bagcilar Teaching and Research Hospital, Istanbul, Bagcilar, Turkey

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