Pregabalin
- Generic Name
- Pregabalin
- Brand Names
- Lyrica, Pregabalin Accord, Pregabalin Pfizer, Pregabalin Sandoz, Pregabalin Mylan, Pregabalin Zentiva
- Drug Type
- Small Molecule
- Chemical Formula
- C8H17NO2
- CAS Number
- 148553-50-8
- Unique Ingredient Identifier
- 55JG375S6M
- Background
Pregabalin is structurally similar to gamma-aminobutyric acid (GABA) - an inhibitory neurotransmitter. It may be used to manage neuropathic pain, postherpetic neuralgia, and fibromyalgia among other conditions. Although as per the FDA Label the mechanism of action has not been definitively defined, there is evidence that pregabalin exerts its effects by bind...
- Indication
Pregabalin is indicated for the management of neuropathic pain associated with diabetic peripheral neuropathy, postherpetic neuralgia, fibromyalgia, neuropathic pain associated with spinal cord injury, and as adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older.
- Associated Conditions
- Diabetic Peripheral Neuropathic Pain (DPN), Epilepsies, Fibromyalgia, Generalized Anxiety Disorder, Neuropathic Pain, Partial-Onset Seizures, Peripheral Neuropathic Pain, Peripheral neuropathy, Postherpetic Neuralgia
- Associated Therapies
- -
A Study Following Women in Menopause Treated With a Non-hormonal Therapy for Hot Flashes and Night Sweats
- Conditions
- Interventions
- Drug: FezolinetantDrug: ParoxetineDrug: GabapentinDrug: CitalopramDrug: ClonidineDrug: PregabalinDrug: EscitalopramDrug: DesvenlafaxineDrug: OxybutyninDrug: Any other non-hormonal pharmacologic therapy prescribed for the treatment of VMS not included in a category aboveDrug: VenlafaxineDrug: Any other SSRI/SNRI not already specified
- First Posted Date
- 2023-09-22
- Last Posted Date
- 2024-12-17
- Lead Sponsor
- Astellas Pharma Global Development, Inc.
- Target Recruit Count
- 1000
- Registration Number
- NCT06049797
- Locations
- 🇺🇸
Washington University School of Medicine, Saint Louis, Missouri, United States
🇺🇸SUNY Downstate Health Sciences University, Brooklyn, New York, United States
🇺🇸Mohawk Valley Health System - Womens Health Center, Utica, New York, United States
Investigation of Treating Chronic Fatigue Syndrome After COVID With Pharmacotherapy (Pregabalin) or Complex Rehabilitation
- First Posted Date
- 2023-08-01
- Last Posted Date
- 2023-11-14
- Target Recruit Count
- 132
- Registration Number
- NCT05967052
- Locations
- 🇵🇱
Centrum Wsparcia Badań Klinicznych, Warsaw, Mazowieckie, Poland
The Efficacy of Tianeptine Versus Pregabalin on Acute and Chronic Post Mastectomy Pain After Breast Cancer Surgery.
- Conditions
- Interventions
- First Posted Date
- 2023-07-07
- Last Posted Date
- 2024-04-22
- Lead Sponsor
- National Cancer Institute, Egypt
- Target Recruit Count
- 90
- Registration Number
- NCT05935059
- Locations
- 🇪🇬
National Cancer Institute Cairo University, Cairo, Egypt
The Effect of Dexmedetomidine, Melatonin and Pregabalin
- Conditions
- Interventions
- First Posted Date
- 2023-04-25
- Last Posted Date
- 2023-04-25
- Lead Sponsor
- Egymedicalpedia
- Target Recruit Count
- 120
- Registration Number
- NCT05829148
- Locations
- 🇪🇬
Al-Azhar University hospitals, Cairo, Egypt
Evaluation of Efficacy and Safety of VX-548 for Painful Diabetic Peripheral Neuropathy (DPN)
- Conditions
- Interventions
- First Posted Date
- 2022-12-21
- Last Posted Date
- 2024-10-11
- Lead Sponsor
- Vertex Pharmaceuticals Incorporated
- Target Recruit Count
- 192
- Registration Number
- NCT05660538
- Locations
- 🇺🇸
University Clinical Investigators, Tustin, California, United States
🇺🇸Velocity Clinical Research - Medford, Medford, Oregon, United States
🇺🇸Synexus - Orlando, Orlando, Florida, United States
Pregabalin Versus Dexmedetomidine for Delirium Treatment After Coronary Artery Bypass Grafting
- Conditions
- Interventions
- First Posted Date
- 2022-12-07
- Last Posted Date
- 2023-04-18
- Lead Sponsor
- Tanta University
- Target Recruit Count
- 70
- Registration Number
- NCT05640453
- Locations
- 🇪🇬
Islam Morsy, Tanta, El-Gharbia Governorate, Egypt
Pregabalin Versus Dexmedetomidine for Delirium Prevention After Cardiac Surgery
- Conditions
- Interventions
- First Posted Date
- 2022-12-07
- Last Posted Date
- 2024-12-04
- Lead Sponsor
- Tanta University
- Target Recruit Count
- 60
- Registration Number
- NCT05640479
- Locations
- 🇪🇬
Tanta University, Tanta, ElGharbiaa, Egypt
Opioid-Free Pain Protocol After Shoulder Arthroplasty
- First Posted Date
- 2022-08-05
- Last Posted Date
- 2024-01-12
- Lead Sponsor
- Henry Ford Health System
- Target Recruit Count
- 80
- Registration Number
- NCT05488847
- Locations
- 🇺🇸
Henry Ford Health, Detroit, Michigan, United States
Comparing Pregabalin and Placebo in Patients With Persistent Globus Sensation
- First Posted Date
- 2022-06-27
- Last Posted Date
- 2022-07-06
- Lead Sponsor
- Universitaire Ziekenhuizen KU Leuven
- Target Recruit Count
- 90
- Registration Number
- NCT05432843
- Locations
- 🇧🇪
Annelies Geeraerts, Leuven, Belgium
🇧🇪University Hospital Leuven, Leuven, België, Belgium
Drug-Drug Interaction Study of "CG-651" in Healthy Volunteer
- First Posted Date
- 2022-05-11
- Last Posted Date
- 2022-05-31
- Lead Sponsor
- CrystalGenomics, Inc.
- Target Recruit Count
- 47
- Registration Number
- NCT05370716
- Locations
- 🇰🇷
Seoul National University Hospital, Seoul, Korea, Republic of
Drug Development Updates
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