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Children's Oncology Group

🇺🇸United States

Country: 🇺🇸United States

Ownership: -

Employees: -

Market Cap: -

Website

Clinical Trials

Combination Chemotherapy in Treating Children With Acute Lymphocytic Leukemia

Phase 3

Completed

Conditions: Leukemia

Interventions: Drug: asparaginase
Drug: cyclophosphamide
Drug: cytarabine
Drug: daunorubicin hydrochloride
Drug: dexamethasone
Drug: doxorubicin hydrochloride
Drug: idarubicin
Drug: mercaptopurine
Drug: methotrexate
Drug: pegaspargase
Drug: prednisone
Drug: thioguanine
Drug: vincristine sulfate
Radiation: radiation therapy

First Posted Date: 2003-11-24

Last Posted Date: 2013-08-26

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 2078

Registration Number: NCT00002812

Locations: 🇺🇸
Long Beach Memorial Medical Center, Long Beach, California, United States
🇺🇸
Children's Hospital Los Angeles, Los Angeles, California, United States
🇺🇸
Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, California, United States

and more 32 locations

Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Infants With Malignant Brain or Spinal Cord Tumors

Phase 1

Completed

Conditions: Brain Tumors
Central Nervous System Tumors
Neuroblastoma
Sarcoma

Interventions: Biological: filgrastim
Drug: carboplatin
Drug: cisplatin
Drug: cyclophosphamide
Drug: etoposide
Drug: thiotepa
Drug: vincristine sulfate
Procedure: conventional surgery
Procedure: peripheral blood stem cell transplantation

First Posted Date: 2003-11-06

Last Posted Date: 2014-03-28

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 94

Registration Number: NCT00003141

Locations: 🇺🇸
City of Hope Comprehensive Cancer Center, Duarte, California, United States
🇺🇸
Childrens Hospital Los Angeles, Los Angeles, California, United States
🇺🇸
Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai Medical Center, Los Angeles, California, United States

and more 68 locations

Surgery and/or Chemotherapy in Treating Children With Infantile, Congenital, or Childhood Fibrosarcoma

Phase 2

Terminated

Conditions: Sarcoma

Interventions: Biological: dactinomycin
Drug: cyclophosphamide
Drug: etoposide
Drug: ifosfamide
Drug: vincristine sulfate
Procedure: Conventional Surgery
Biological: MESNA (mercaptoethane sulfonate)
Biological: Filgrastim

First Posted Date: 2003-11-06

Last Posted Date: 2014-09-30

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 7

Registration Number: NCT00072280

Locations: 🇺🇸
Phoenix Children's Hospital, Phoenix, Arizona, United States
🇺🇸
Arkansas Cancer Research Center at University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States
🇺🇸
Southern California Permanente Medical Group, Downey, California, United States

and more 71 locations

Systemic Chemotherapy and Subtenon Carboplatin, and Local Ophthalmic Therapy in Children With Intraocular Retinoblastoma

Phase 3

Completed

Conditions: Intraocular Retinoblastoma

Interventions: Drug: liposomal vincristine sulfate
Procedure: cryosurgery
Procedure: laser surgery
Drug: carboplatin
Drug: etoposide
Biological: filgrastim

First Posted Date: 2003-11-06

Last Posted Date: 2021-07-30

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 30

Registration Number: NCT00072384

Locations: 🇺🇸
Children's Oncology Group, Arcadia, California, United States
🇺🇸
Southern California Permanente Medical Group, Downey, California, United States
🇺🇸
Children's Hospital Los Angeles, Los Angeles, California, United States

and more 8 locations

Vinorelbine in Treating Children With Recurrent or Refractory Cancers

Phase 2

Completed

Conditions: Neuroblastoma
Sarcoma
Brain and Central Nervous System Tumors

Interventions: Drug: vinorelbine tartrate

First Posted Date: 2003-10-28

Last Posted Date: 2014-07-28

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 50

Registration Number: NCT00003234

Locations: 🇺🇸
University of Alabama at Birmingham Comprehensive Cancer Center, Birmingham, Alabama, United States
🇺🇸
University of South Alabama Medical Center, Mobile, Alabama, United States
🇺🇸
Phoenix Children's Hospital, Phoenix, Arizona, United States

and more 224 locations

Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Neuroblastoma

Phase 2

Completed

Conditions: Neuroblastoma

Interventions: Biological: filgrastim
Biological: sargramostim
Drug: carboplatin
Drug: cisplatin
Drug: cyclophosphamide
Drug: doxorubicin hydrochloride
Drug: etoposide
Drug: etoposide phosphate
Drug: ifosfamide
Drug: isotretinoin
Drug: melphalan
Drug: thiotepa
Drug: vincristine sulfate
Procedure: conventional surgery
Procedure: peripheral blood stem cell transplantation
Radiation: radiation therapy

First Posted Date: 2003-10-09

Last Posted Date: 2014-02-13

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 42

Registration Number: NCT00017368

Locations: 🇺🇸
AFLAC Cancer Center and Blood Disorders Service of Children's Healthcare of Atlanta - Scottish RiteCampus, Atlanta, Georgia, United States
🇺🇸
Floating Hospital for Children, Boston, Massachusetts, United States
🇺🇸
Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute, Boston, Massachusetts, United States

and more 6 locations

Immunotherapy Using Cyclosporine, Interferon Gamma, and Interleukin-2 After High-Dose Myeloablative Chemotherapy With Autologous Stem Cell Transplantation in Treating Patients With Refractory or Relapsed Hodgkin's Lymphoma

Phase 2

Completed

Conditions: Lymphoma

Interventions: Biological: aldesleukin
Biological: filgrastim
Biological: recombinant interferon gamma
Drug: carmustine
Drug: cyclosporine
Drug: cytarabine
Drug: etoposide
Drug: melphalan
Procedure: autologous bone marrow transplantation
Procedure: bone marrow ablation with stem cell support
Procedure: peripheral blood stem cell transplantation

First Posted Date: 2003-10-07

Last Posted Date: 2013-10-17

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 24

Registration Number: NCT00070187

Locations: 🇺🇸
Comprehensive Cancer Center at University of Alabama at Birmingham, Birmingham, Alabama, United States
🇺🇸
Phoenix Children's Hospital, Phoenix, Arizona, United States
🇺🇸
Arkansas Cancer Research Center at University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States

and more 60 locations

Pemetrexed Disodium in Treating Young Patients With Recurrent Solid Tumors

Phase 1

Completed

Conditions: Unspecified Childhood Solid Tumor, Protocol Specific

First Posted Date: 2003-10-07

Last Posted Date: 2014-02-20

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 33

Registration Number: NCT00070473

Locations: 🇺🇸
Children's Hospital Los Angeles, Los Angeles, California, United States
🇺🇸
Stanford Cancer Center at Stanford University Medical Center, Stanford, California, United States
🇺🇸
Children's National Medical Center, Washington, District of Columbia, United States

and more 17 locations

Gemtuzumab Ozogamicin in Treating Young Patients With Newly Diagnosed Acute Myeloid Leukemia Undergoing Remission Induction and Intensification Therapy

Phase 2

Completed

Conditions: Leukemia

First Posted Date: 2003-10-07

Last Posted Date: 2014-02-20

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 350

Registration Number: NCT00070174

Locations: 🇺🇸
Comprehensive Cancer Center at University of Alabama at Birmingham, Birmingham, Alabama, United States
🇺🇸
Phoenix Children's Hospital, Phoenix, Arizona, United States
🇺🇸
Arkansas Cancer Research Center at University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States

and more 145 locations

Induction Chemotherapy Using Cyclophosphamide and Topotecan in Treating Patients Who Are Undergoing Autologous Peripheral Stem Cell Transplantation for Newly Diagnosed or Progressive Neuroblastoma

Phase 1

Completed

Conditions: Neuroblastoma

Interventions: Biological: filgrastim
Drug: cisplatin
Drug: cyclophosphamide
Drug: doxorubicin hydrochloride
Drug: etoposide
Drug: isotretinoin
Drug: melphalan
Drug: topotecan hydrochloride
Drug: vincristine sulfate
Procedure: conventional surgery
Procedure: peripheral blood stem cell transplantation
Radiation: radiation therapy

First Posted Date: 2003-10-07

Last Posted Date: 2014-02-13

Lead Sponsor: Children's Oncology Group

Target Recruit Count: 31

Registration Number: NCT00070200

Locations: 🇺🇸
UCSF Comprehensive Cancer Center, San Francisco, California, United States
🇺🇸
Children's Memorial Hospital - Chicago, Chicago, Illinois, United States
🇺🇸
St. Jude Children's Research Hospital, Memphis, Tennessee, United States

and more 3 locations

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