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Brentuximab Vedotin and Combination Chemotherapy in Treating Older Patients With Previously Untreated Stage II-IV Hodgkin Lymphoma

Phase 2
Conditions
Adult Lymphocyte Depletion Hodgkin Lymphoma
Adult Lymphocyte Predominant Hodgkin Lymphoma
Adult Mixed Cellularity Hodgkin Lymphoma
Adult Nodular Sclerosis Hodgkin Lymphoma
Stage II Adult Hodgkin Lymphoma
Stage III Adult Hodgkin Lymphoma
Stage IV Adult Hodgkin Lymphoma
Interventions
Procedure: quality-of-life assessment
Genetic: DNA analysis
Genetic: RNA analysis
Radiation: fludeoxyglucose F 18
Procedure: positron emission tomography
Other: laboratory biomarker analysis
Other: immunohistochemistry staining method
Genetic: polymorphism analysis
First Posted Date
2011-11-22
Last Posted Date
2020-02-17
Lead Sponsor
Northwestern University
Target Recruit Count
48
Registration Number
NCT01476410
Locations
🇺🇸

University of Chicago, Chicago, Illinois, United States

🇺🇸

Stanford University Medical Center, Stanford, California, United States

🇺🇸

Memorial Sloan- Kettering Cancer Center, New York, New York, United States

and more 4 locations

A Clinical Trial Comparing the Efficacy of Darunavir/Ritonavir Monotherapy Versus a Triple Combination Therapy Containing Darunavir/Ritonavir and 2 Nucleoside/Nucleotide Reverse Transcriptase Inhibitors in Patients With Undetectable Plasma HIV-1 RNA on Current Treatment

Phase 3
Completed
Conditions
Acquired Immunodeficiency Syndrome (AIDS) Virus
Human Immunodeficiency Virus (HIV) Infections
Interventions
First Posted Date
2011-10-07
Last Posted Date
2017-11-27
Lead Sponsor
Janssen-Cilag International NV
Target Recruit Count
274
Registration Number
NCT01448707

Study of Tissue Samples From Patients With Non-Small Cell Lung Cancer

Completed
Conditions
Lung Cancer
Interventions
Genetic: DNA analysis
Genetic: DNA methylation analysis
Genetic: RNA analysis
Genetic: gene expression analysis
Genetic: polymorphism analysis
Other: laboratory biomarker analysis
Other: medical chart review
First Posted Date
2011-08-11
Last Posted Date
2017-06-27
Lead Sponsor
Alliance for Clinical Trials in Oncology
Target Recruit Count
248
Registration Number
NCT01414595
Locations
🇺🇸

Union Hospital of Cecil County, Elkton, Maryland, United States

🇺🇸

Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai Medical Center, Los Angeles, California, United States

🇺🇸

Greenebaum Cancer Center at University of Maryland Medical Center, Baltimore, Maryland, United States

and more 8 locations

HIV Diagnosis in Hospitalized Malawian Infants

Not Applicable
Completed
Conditions
HIV Infections
Interventions
Device: Point of care HIV RNA PCR
First Posted Date
2011-07-06
Last Posted Date
2013-05-14
Lead Sponsor
University of North Carolina, Chapel Hill
Target Recruit Count
300
Registration Number
NCT01388452
Locations
🇲🇼

Kamuzu Central Hospital, Lilongwe, Malawi

Sirolimus and Gold Sodium Thiomalate in Treating Patients With Advanced Squamous Non-Small Cell Lung Cancer

Phase 1
Withdrawn
Conditions
Recurrent Non-small Cell Lung Cancer
Stage IIIA Non-small Cell Lung Cancer
Squamous Cell Lung Cancer
Stage IIIB Non-small Cell Lung Cancer
Stage IV Non-small Cell Lung Cancer
Unspecified Adult Solid Tumor, Protocol Specific
Interventions
Other: pharmacological study
Genetic: RNA analysis
Genetic: polymerase chain reaction
First Posted Date
2011-06-28
Last Posted Date
2020-04-01
Lead Sponsor
Mayo Clinic
Registration Number
NCT01383668

Autologous Redirected RNA Meso-CIR T Cells

Phase 1
Completed
Conditions
Malignant Pleural Mesothelioma
Interventions
Biological: Autologous T cells
First Posted Date
2011-05-19
Last Posted Date
2017-09-19
Lead Sponsor
University of Pennsylvania
Target Recruit Count
18
Registration Number
NCT01355965
Locations
🇺🇸

Abramson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania, United States

Qualitative and Quantitative HIV RNA Detection in Saliva Using the Oragene RNA Kit

Completed
Conditions
HIV Infections
First Posted Date
2011-04-29
Last Posted Date
2011-04-29
Lead Sponsor
Ottawa Hospital Research Institute
Target Recruit Count
40
Registration Number
NCT01344642
Locations
🇨🇦

The Ottawa Hospital, General Campus, Ottawa, Ontario, Canada

Combination Chemotherapy and Pralatrexate as First-Line Therapy in Treating Patients With Non-Hodgkin Lymphoma

Phase 2
Completed
Conditions
Anaplastic Large Cell Lymphoma
Hepatosplenic T-cell Lymphoma
Angioimmunoblastic T-cell Lymphoma
Peripheral T-cell Lymphoma
Interventions
Other: laboratory biomarker analysis
Genetic: comparative genomic hybridization
Genetic: gene expression analysis
Genetic: nucleic acid sequencing
Genetic: mutation analysis
Other: immunohistochemistry staining method
Genetic: microarray analysis
Genetic: RNA analysis
First Posted Date
2011-04-18
Last Posted Date
2023-09-22
Lead Sponsor
University of Nebraska
Target Recruit Count
34
Registration Number
NCT01336933
Locations
🇺🇸

University of Massachusetts Medical School, Worcester, Massachusetts, United States

🇺🇸

University of Chicago, Chicago, Illinois, United States

🇺🇸

Mayo Clinic, Rochester, Minnesota, United States

and more 6 locations

Biomarkers in Tissue Samples From Young Patients With Liver Cancer

Completed
Conditions
Childhood Hepatoblastoma
Stage I Childhood Liver Cancer
Stage III Childhood Liver Cancer
Stage IV Childhood Liver Cancer
Stage II Childhood Liver Cancer
Interventions
Genetic: RNA analysis
Genetic: gene expression analysis
Genetic: microarray analysis
Genetic: nucleic acid sequencing
Other: diagnostic laboratory biomarker analysis
First Posted Date
2011-04-18
Last Posted Date
2016-05-18
Lead Sponsor
Children's Oncology Group
Target Recruit Count
99
Registration Number
NCT01336881
Locations
🇺🇸

Children's Oncology Group, Monrovia, California, United States

The Effect of Vorinostat on HIV RNA Expression in the Resting CD4+ T Cells of HIV+ Pts on Stable ART

Phase 1
Completed
Conditions
HIV-1 Infection
Interventions
First Posted Date
2011-03-21
Last Posted Date
2017-06-29
Lead Sponsor
University of North Carolina, Chapel Hill
Target Recruit Count
25
Registration Number
NCT01319383
Locations
🇺🇸

The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States

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