Sevoflurane
- Generic Name
- Sevoflurane
- Brand Names
- Sevorane, Sojourn, Ultane
- Drug Type
- Small Molecule
- Chemical Formula
- C4H3F7O
- CAS Number
- 28523-86-6
- Unique Ingredient Identifier
- 38LVP0K73A
- Background
Sevoflurane is an ether inhalation anesthetic agent used to induce and maintain general anesthesia. It is a volatile, non-flammable compound with a low solubility profile and blood/gas partition coefficient. Sevoflurane was patented in 1972, was approved for clinical use in Japan in 1990, and approved by the FDA in 1996. Sevoflurane is three times more potent than desflurane, but has lower potency compared to halothane and isoflurane. Unlike other volatile anesthetics, sevoflurane has a pleasant odor and does not irritate the airway. The hemodynamic and respiratory depressive effects of sevoflurane are well tolerated, and most patients receiving this anesthetic agent present little toxicity. Therefore, it can be used for inhalational induction in adults and children for a wide variety of anesthetic procedures.
- Indication
Sevoflurane is used for the induction and maintenance of general anesthesia in adult and pediatric patients for inpatient and outpatient surgery.
- Associated Conditions
- -
- Associated Therapies
- General Anesthesia, Induction and Maintenance of General Anesthesia
Influence of Sevoflurane and Desflurane on Postoperative Sore Throat
- First Posted Date
- 2017-08-24
- Last Posted Date
- 2017-08-24
- Lead Sponsor
- Keimyung University Dongsan Medical Center
- Target Recruit Count
- 100
- Registration Number
- NCT03259672
Benefits of Total Intravenous Anesthesia Compared With Inhaled Anesthesia in Cardiovascular Surgery
- Conditions
- Interventions
- First Posted Date
- 2017-07-31
- Last Posted Date
- 2020-08-06
- Lead Sponsor
- Coordinación de Investigación en Salud, Mexico
- Target Recruit Count
- 40
- Registration Number
- NCT03233815
- Locations
- 🇲🇽
Hospital de cardiología, Ciudad de mexico, Cdmx, Mexico
Comparison Between Target-controlled Infusion of Propofol and Sevoflurane as Maintenance of Anesthesia to Hemodynamic Profile of Renal Transplant Recipient
- Conditions
- Interventions
- First Posted Date
- 2017-07-11
- Last Posted Date
- 2018-02-28
- Lead Sponsor
- Indonesia University
- Target Recruit Count
- 23
- Registration Number
- NCT03214653
- Locations
- 🇮🇩
Cipto Mangunkusumo Central National Hospital, Jakarta, DKI Jakarta, Indonesia
Effect of Anesthetics on Microcirculation in Patients Undergoing Off-pump Coronary Artery Bypass Surgery
- Conditions
- Interventions
- First Posted Date
- 2017-07-06
- Last Posted Date
- 2020-03-04
- Lead Sponsor
- Seoul National University Hospital
- Target Recruit Count
- 72
- Registration Number
- NCT03209193
- Locations
- 🇰🇷
Seoul National University Hospital, Seoul, Korea, Republic of
The Effects of General Anesthetics on Lymphocytes in Patients Undergoing Colorectal Cancer Resection and Mechanism Involved
- First Posted Date
- 2017-06-21
- Last Posted Date
- 2017-11-06
- Lead Sponsor
- Guizhi Du
- Target Recruit Count
- 260
- Registration Number
- NCT03193710
- Locations
- 🇨🇳
West China Hospital of Sichuan University, Department of Anesthesiology, Chengdu, Sichuan, China
Appropriate Compatibility of Propofol and Sevoflurane for Orthopaedic Surgery of Patients With MCI
- First Posted Date
- 2017-05-24
- Last Posted Date
- 2018-05-25
- Target Recruit Count
- 100
- Registration Number
- NCT03165396
- Locations
- 🇨🇳
Third Central Hospital of Tianjin, Tianjin, Tianjin, China
Comparison of Propofol and Sevoflurane as Maintaining Anesthetics During General Anesthesia of Cesarean Section
- First Posted Date
- 2017-05-11
- Last Posted Date
- 2018-06-12
- Lead Sponsor
- Tao Zhang
- Target Recruit Count
- 60
- Registration Number
- NCT03149588
- Locations
- 🇨🇳
First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China
The Effects of Different Anesthetic Techniques on QT, Corrected QT (QTc), and P Wave Dispersions in Cesarean Section
- Conditions
- Interventions
- First Posted Date
- 2017-05-01
- Last Posted Date
- 2017-05-09
- Lead Sponsor
- Trakya University
- Target Recruit Count
- 90
- Registration Number
- NCT03134677
The Epigenetic Modification in OPRM1 on Postoperative Analgesia and Side Effect Induced by Sufentanil
- First Posted Date
- 2017-05-01
- Last Posted Date
- 2017-05-01
- Lead Sponsor
- Huazhong University of Science and Technology
- Target Recruit Count
- 100
- Registration Number
- NCT03135795
- Locations
- 🇨🇳
Department of Anaesthesiology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
Does Sevoflurane Cause Genomic Damage
- First Posted Date
- 2017-04-12
- Last Posted Date
- 2019-01-14
- Target Recruit Count
- 30
- Registration Number
- NCT03109119
- Locations
- 🇮🇳
Jubilee Mission Medical College and Research Institute, Thrissur, Kerala, India
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.