Sevoflurane

Generic Name
Sevoflurane
Brand Names
Sevorane, Sojourn, Ultane
Drug Type
Small Molecule
Chemical Formula
C4H3F7O
CAS Number
28523-86-6
Unique Ingredient Identifier
38LVP0K73A
Background

Sevoflurane is an ether inhalation anesthetic agent used to induce and maintain general anesthesia. It is a volatile, non-flammable compound with a low solubility profile and blood/gas partition coefficient. Sevoflurane was patented in 1972, was approved for clinical use in Japan in 1990, and approved by the FDA in 1996. Sevoflurane is three times more poten...

Indication

Sevoflurane is used for the induction and maintenance of general anesthesia in adult and pediatric patients for inpatient and outpatient surgery.

Associated Conditions
-
Associated Therapies
General Anesthesia, Induction and Maintenance of General Anesthesia

Sevoflurane in Cardiac Surgery

Phase 4
Completed
Conditions
Interventions
First Posted Date
2009-01-13
Last Posted Date
2015-10-14
Lead Sponsor
Università Vita-Salute San Raffaele
Target Recruit Count
200
Registration Number
NCT00821262
Locations
🇮🇹

Azienda Ospedaliera di Padova, Padova, Italy

🇮🇹

Vita-Salute University, Milano, Italy

🇮🇹

Azienda Ospedaliera di Perugia (H Santa Maria della Misericordia), Perugia, Italy

and more 2 locations

Vasodilation Effect of Inhalational Anesthetics

First Posted Date
2008-12-29
Last Posted Date
2009-12-23
Lead Sponsor
Nanjing Medical University
Target Recruit Count
300
Registration Number
NCT00815269
Locations
🇨🇳

Nanjing Maternal and Child Health Care Hospital, Nanjing, Jiangsu, China

Depth of Hypnosis and Postoperative Nausea and Vomiting During Xenon Anaesthesia

First Posted Date
2008-11-19
Last Posted Date
2011-05-17
Lead Sponsor
RWTH Aachen University
Target Recruit Count
220
Registration Number
NCT00793663
Locations
🇩🇪

RWTH Aachen University; Department of Anesthesiology, Aachen, Germany

Evaluation of Different Anesthesia for Uterine Curettage

First Posted Date
2008-08-13
Last Posted Date
2009-03-31
Lead Sponsor
Nanjing Medical University
Target Recruit Count
150
Registration Number
NCT00733564
Locations
🇨🇳

Nanjing Maternal and Child Health Care Hospital, Nanjing, Jiangsu, China

Propofol Versus Volatile Anesthesia in Post Operative Pain Management

Not Applicable
Terminated
Conditions
Interventions
First Posted Date
2008-07-10
Last Posted Date
2016-07-20
Lead Sponsor
The Cleveland Clinic
Target Recruit Count
90
Registration Number
NCT00712517
Locations
🇦🇹

Olga Plattner , MD, Vienna, Austria

Sevoflurane and Laryngeal Reflex Responses in Pediatric Patients

Phase 4
Terminated
Conditions
Interventions
First Posted Date
2008-04-23
Last Posted Date
2009-03-12
Lead Sponsor
University Hospital, Basel, Switzerland
Target Recruit Count
40
Registration Number
NCT00665418

Comparison of Sevoflurane and Isoflurane Anesthesia for Benign Breast Tumor Excision

Phase 4
Completed
Conditions
Interventions
First Posted Date
2007-12-18
Last Posted Date
2008-04-21
Lead Sponsor
Nanjing Medical University
Target Recruit Count
500
Registration Number
NCT00575354
Locations
🇨🇳

Nanjing Maternal and Child Care Hospital, Nanjing, Jiangsu, China

Continuous Versus Repetitive Sevoflurane Administration for Preconditioning

Phase 4
Completed
Conditions
Interventions
First Posted Date
2007-12-07
Last Posted Date
2007-12-07
Lead Sponsor
University Hospital Schleswig-Holstein
Target Recruit Count
50
Registration Number
NCT00569816
Locations
🇩🇪

University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany

Sugammadex After Continuous Infusion of Rocuronium During Sevoflurane and Propofol Anesthesia (P05949; MK-8616-028)

First Posted Date
2007-11-16
Last Posted Date
2019-11-25
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
52
Registration Number
NCT00559468
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