Propofol
- Generic Name
- Propofol
- Brand Names
- Diprivan
- Drug Type
- Small Molecule
- Chemical Formula
- C12H18O
- CAS Number
- 2078-54-8
- Unique Ingredient Identifier
- YI7VU623SF
- Background
Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. drowsiness, nausea, vomiting) than with thiopental, methohexital, and etomidate. Propofol may be used prior to diagnostic procedures requiring anaesthesia, in the management of refractory status epilepticus, and for induction and/or maintenance of anaesthesia prior to and during surgeries.
- Indication
Used for induction and/or maintenance of anaesthesia and for management of refractory status epilepticus.
- Associated Conditions
- -
- Associated Therapies
- Induction of anesthesia therapy, Maintenance of anesthesia therapy, Monitored anesthesia care sedation, Sedative therapy
The Relationship Between Different Doses of Propofol and the Occurrence of Dreams in Short Surgery Under General Anesthesia
- First Posted Date
- 2021-12-30
- Last Posted Date
- 2022-06-02
- Lead Sponsor
- Shengjing Hospital
- Target Recruit Count
- 300
- Registration Number
- NCT05173688
- Locations
- 🇨🇳
Shengjing Hospital, Shenyang, Liaoning, China
The Comparison of Hypotension Incidence Between Remimazolam and Propofol in Hypertensive Patients Undergoing Neurosurgery
- Conditions
- Interventions
- First Posted Date
- 2021-12-20
- Last Posted Date
- 2022-11-07
- Lead Sponsor
- Yonsei University
- Target Recruit Count
- 100
- Registration Number
- NCT05164146
- Locations
- 🇰🇷
Yonsei University Health System, Severance Hospital, Seoul, Korea, Republic of
Inhibitory Effect of Propofol on Perineal Pruritus in Patients Undergoing Day Surgery
- First Posted Date
- 2021-12-17
- Last Posted Date
- 2021-12-17
- Lead Sponsor
- Yangzhou University
- Target Recruit Count
- 150
- Registration Number
- NCT05162430
- Locations
- 🇨🇳
Liu meiyu, Yangzhou, Jiangsu, China
Application of the Propofol Precise Infusion Model
- First Posted Date
- 2021-12-15
- Last Posted Date
- 2021-12-15
- Lead Sponsor
- West China Hospital
- Target Recruit Count
- 400
- Registration Number
- NCT05158426
- Locations
- 🇨🇳
West China Hospital of Sichuan University, Chengdu, Sichuan, China
Influences of Propofol and Sevoflurane Anesthesia in Brain Tumor
- First Posted Date
- 2021-12-02
- Last Posted Date
- 2023-10-31
- Target Recruit Count
- 706
- Registration Number
- NCT05141877
- Locations
- 🇨🇳
Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung, Taiwan
Importance of Integrated Pulmonary Index in Pediatric Endoscopy
- Conditions
- Interventions
- First Posted Date
- 2021-11-30
- Last Posted Date
- 2023-02-28
- Lead Sponsor
- Marmara University
- Target Recruit Count
- 60
- Registration Number
- NCT05137574
- Locations
- 🇹🇷
Marmara University School of Medicine, Istanbul, Pendik, Turkey
Importance of Integrated Pulmonary Index in Pediatric Bronchoscopy
- Conditions
- Interventions
- First Posted Date
- 2021-11-30
- Last Posted Date
- 2023-02-28
- Lead Sponsor
- Marmara University
- Target Recruit Count
- 60
- Registration Number
- NCT05137587
- Locations
- 🇹🇷
Marmara University School of Medicine, Istanbul, Pendik, Turkey
The Effect of Volatile Anesthesia and Total Intravenous Anesthesia on Shedding of the Endothelial Glycocalyx in Patients Undergoing Mastectomy and Breast Reconstruction Using Deep Inferior Epigastric Artery Perforator Free Flap
- Conditions
- Interventions
- First Posted Date
- 2021-11-29
- Last Posted Date
- 2021-11-29
- Lead Sponsor
- Yonsei University
- Target Recruit Count
- 50
- Registration Number
- NCT05136508
- Locations
- 🇰🇷
Yonsei University Health System, Severance Hospital, Seoul, Korea, Republic of
Propofol Versus Sevoflurane for Induction of GA in Infants
- First Posted Date
- 2021-11-03
- Last Posted Date
- 2023-07-05
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 122
- Registration Number
- NCT05105022
- Locations
- 🇪🇬
Faculty of Medicine- Cairo University, Cairo, Egypt
Propofol-remifentanyl Versus Dexmedetomidine in Awake Craniotomy: Impact on Electroclinical Seizure Activity
- Conditions
- Interventions
- First Posted Date
- 2021-11-02
- Last Posted Date
- 2023-01-31
- Target Recruit Count
- 170
- Registration Number
- NCT05103735
- Locations
- 🇮🇹
Cristian Deana, Udine, Italy
Drug Development Updates
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