Propofol

Generic Name
Propofol
Brand Names
Diprivan
Drug Type
Small Molecule
Chemical Formula
C12H18O
CAS Number
2078-54-8
Unique Ingredient Identifier
YI7VU623SF
Background

Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. ...

Indication

Used for induction and/or maintenance of anaesthesia and for management of refractory status epilepticus.

Associated Conditions
-
Associated Therapies
Induction of anesthesia therapy, Maintenance of anesthesia therapy, Monitored anesthesia care sedation, Sedative therapy

Precedex Versus Propofol-Awakening for Reducing Brain Injury Expansion

First Posted Date
2007-10-02
Last Posted Date
2013-04-11
Lead Sponsor
Carmelo Graffagnino
Target Recruit Count
8
Registration Number
NCT00538616
Locations
🇺🇸

Duke University, Durham, North Carolina, United States

Opioid-potentiated Volative Anaesthetic Vs. Remifentanil And Propofol During Abdominal Aortic Aneurysm Surgery

First Posted Date
2007-10-02
Last Posted Date
2013-03-11
Lead Sponsor
Sykehuset i Vestfold HF
Target Recruit Count
193
Registration Number
NCT00538421
Locations
🇳🇴

Sykehuset i Vestfold HF, Tonsberg, Norway

Anesthetics and Auditory, Visceral, and Heat Evoked Potentials

First Posted Date
2007-09-26
Last Posted Date
2007-09-26
Lead Sponsor
Technical University of Munich
Target Recruit Count
60
Registration Number
NCT00534586
Locations
🇩🇪

Technische Universität München, Klinikum rechts der Isar, Department of Anesthesiology, Munich, Bavaria, Germany

Propofol in Emergence Agitation

Phase 4
Completed
Conditions
Interventions
First Posted Date
2007-09-26
Last Posted Date
2019-10-21
Lead Sponsor
University of Wisconsin, Madison
Target Recruit Count
99
Registration Number
NCT00535613
Locations
🇺🇸

Univeristy of Wisconsin - Madison, Madison, Wisconsin, United States

Effects of General Anesthesia and Spinal-Morphine Anesthesia on Recovery and Comfort After Benign Abdominal Hysterectomy

First Posted Date
2007-09-10
Last Posted Date
2012-01-26
Lead Sponsor
Preben Kjolhede
Target Recruit Count
180
Registration Number
NCT00527332
Locations
🇸🇪

Värnamo Hospital, Värnamo, Sweden

🇸🇪

Eksjö Hospital, Eksjö, Sweden

🇸🇪

Ryhov Hospital, Jönköping, Sweden

and more 2 locations

Efficacy and Safety Study of Two Propofol Formulations

Phase 3
Completed
Conditions
Interventions
First Posted Date
2007-07-25
Last Posted Date
2008-02-25
Lead Sponsor
B. Braun Melsungen AG
Target Recruit Count
220
Registration Number
NCT00506246
Locations
🇨🇳

Zhongshan Hospital affiliated to Fudan University, Shanghai, China

🇨🇳

Pekin Union Medical College Hospital, Beijing, China

🇨🇳

Renji Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China

Neuroimaging the Effects of Intravenous Anesthetic on Amygdala Dependent Memory Processes

Phase 4
Terminated
Conditions
Interventions
First Posted Date
2007-07-20
Last Posted Date
2021-07-15
Lead Sponsor
Weill Medical College of Cornell University
Target Recruit Count
60
Registration Number
NCT00504894
Locations
🇺🇸

Weill Cornell Medical College, New York, New York, United States

Inhaled Sevoflurane Compared to Intravenous Sedation Post Coronary Artery Bypass Grafting

First Posted Date
2007-06-11
Last Posted Date
2010-05-20
Lead Sponsor
Karolinska Institutet
Target Recruit Count
100
Registration Number
NCT00484575
Locations
🇸🇪

Karolinska University Hospital Solna, Cardiothoracic Intensive Care Unit, Stockholm, Sweden

Dexmedetomidine Versus Propofol for Continuous Sedation in the Intensive Care Unit (ICU)

First Posted Date
2007-05-28
Last Posted Date
2010-08-13
Lead Sponsor
Orion Corporation, Orion Pharma
Target Recruit Count
500
Registration Number
NCT00479661
Locations
🇷🇺

State Institution B.B. Petrovsky Russian Research Centre of Surgery of RAMS, 2, Abrikosovsky per., Moscow, Russian Federation

🇷🇺

Medical Academy of Postgraduate Study, 41, ulica Kirochnaya,, St. Petersburg, Russian Federation

🇳🇱

Westfries Gasthuis, Department Intensieve Zorgen, Maelsonstraat 3,, Hoorn, Netherlands

and more 37 locations

Early Cardioprotective Effect of Sevoflurane

First Posted Date
2007-05-24
Last Posted Date
2007-05-24
Lead Sponsor
University Hospital Dubrava
Target Recruit Count
32
Registration Number
NCT00477737
Locations
🇭🇷

University Hospital Dubrava, Zagreb, Croatia

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