Propofol

Generic Name
Propofol
Brand Names
Diprivan
Drug Type
Small Molecule
Chemical Formula
C12H18O
CAS Number
2078-54-8
Unique Ingredient Identifier
YI7VU623SF
Background

Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. ...

Indication

Used for induction and/or maintenance of anaesthesia and for management of refractory status epilepticus.

Associated Conditions
-
Associated Therapies
Induction of anesthesia therapy, Maintenance of anesthesia therapy, Monitored anesthesia care sedation, Sedative therapy
Clinical Trials
Related News

Post Operative Hemodynamic Function After Anesthetic Induction With Etomidate for Cardiac Surgery With ECC

Phase 4
Completed
Conditions
Cardiac Surgery
Interventions
Drug: etomidate
Drug: propofol
First Posted Date
2007-03-23
Last Posted Date
2008-10-31
Lead Sponsor
Centre Hospitalier Universitaire de Saint Etienne
Target Recruit Count
100
Registration Number
NCT00451776
Locations
🇫🇷

University hospital, Saint-Etienne, France

Dreaming and EEG Changes During Anaesthesia Maintained With Propofol or Desflurane

Phase 4
Completed
Conditions
Anaesthesia
Interventions
Drug: Propofol
Drug: desflurane
First Posted Date
2007-03-12
Last Posted Date
2013-05-30
Lead Sponsor
Melbourne Health
Target Recruit Count
300
Registration Number
NCT00446212
Locations
🇦🇺

Royal Perth Hospital, Perth, Western Australia, Australia

🇳🇿

Waikato Hospital, Hamilton, New Zealand

🇦🇺

Royal Melbourne Hospital, Parkville, Victoria, Australia

and more 1 locations

Anesthesia in Flexible Bronchoscopy for Lung Cancer Diagnostic

Phase 4
Completed
Conditions
Lung Cancer
First Posted Date
2007-02-27
Last Posted Date
2007-02-27
Lead Sponsor
Hospital Pompeia
Registration Number
NCT00440960
Locations
🇧🇷

Hospital Pompeia, Caxias do Sul, RS, Brazil

🇧🇷

Hospital Medianeira, Caxias do Sul, RS, Brazil

🇧🇷

General Hospital of Universidade de Caxias do Sul, Caxias do Sul, RS, Brazil

Pharmacoeconomic Consequences Of Analgesia in the Intensive Care Unit (ICU)

Phase 3
Terminated
Conditions
Analgesia
Interventions
Drug: Propofol
Drug: Remifentanil
First Posted Date
2007-02-19
Last Posted Date
2017-05-30
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
39
Registration Number
NCT00436345
Locations
🇮🇹

GSK Investigational Site, Palermo, Sicilia, Italy

Neuronal Mechanisms of Sensory Processing During General Anesthesia

Not Applicable
Conditions
General Anesthesia
First Posted Date
2007-02-13
Last Posted Date
2010-07-30
Lead Sponsor
Ludwig-Maximilians - University of Munich
Target Recruit Count
768
Registration Number
NCT00434382
Locations
🇩🇪

Klinik fuer Anaesthesiologie am Universitätsklinikum Schleswig Holstein, Campus Luebeck, Lubeck, Germany

🇩🇪

Klinik fuer Anaesthesiologie der Ludwigs-Maximilians-Universitaet Muenchen, Munich, Germany

🇩🇪

Krankenhaus Friedrichshafen, Friedrichshafen, Germany

and more 1 locations

Is Dexmedetomidine Associated With a Lower Incidence of Postoperative Delirium When Compared to Propofol or Midazolam in Cardiac Surgery Patients

First Posted Date
2007-01-04
Last Posted Date
2022-05-27
Lead Sponsor
Stanford University
Target Recruit Count
90
Registration Number
NCT00417664
Locations
🇺🇸

Stanford University Medical Center, Stanford, California, United States

Effect of Etomidate on Hemodynamics and Adrenocortical Function After Cardiac Surgery

First Posted Date
2006-12-25
Last Posted Date
2010-03-04
Lead Sponsor
Insel Gruppe AG, University Hospital Bern
Target Recruit Count
130
Registration Number
NCT00415701
Locations
🇨🇭

Departments of Intensive Care Medicine and Anesthesiology, Bern, BE, Switzerland

EEG and Auditory Evoked Potentials During Local Anesthesia

Phase 4
Conditions
Healthy
First Posted Date
2006-12-08
Last Posted Date
2006-12-08
Lead Sponsor
Technical University of Munich
Target Recruit Count
15
Registration Number
NCT00408941
Locations
🇩🇪

Technische Universität München, Klinikum rechts der Isar, Department of Anesthesiology, Munich, Bavaria, Germany

Organ Protection for Coronary Artery Bypass Graft (CABG): Propofol Versus Desflurane

First Posted Date
2006-11-17
Last Posted Date
2010-06-29
Lead Sponsor
University of Melbourne
Target Recruit Count
182
Registration Number
NCT00400790
Locations
🇦🇺

Royal Melbourne Hospital, Melbourne, Victoria, Australia

Population PK/PD of Propofol in the Morbidly Obese Patient

Phase 4
Completed
Conditions
Morbid Obesity
Interventions
Drug: Diprivan
First Posted Date
2006-11-03
Last Posted Date
2010-10-22
Lead Sponsor
St. Antonius Hospital
Target Recruit Count
20
Registration Number
NCT00395681
Locations
🇳🇱

st. Antonius hospital, Nieuwegein, Netherlands

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